Article
Psychiatry
Marko Elovainio, Jari Lipsanen, Laura Pulkki-Raback, Jaana Suvisaari, Christian Hakulinen
Summary: The study found that differences in symptom thresholds and autoregressive loops may be more significant than symptom connectivity in distinguishing individuals with and without depressive disorders. This suggests that the activation of symptoms over time may be influenced more by certain features like thresholds and autoregressive loops rather than symptom connections.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Review
Psychology, Clinical
Debbie Huang, Ezra Susser, Kara E. Rudolph, Katherine M. Keyes
Summary: The network paradigm considers psychiatric disorders as being caused by interconnected symptoms. However, studies on depression within this paradigm have not sufficiently addressed the necessary assumptions for causal inference. The lack of discussion and testing of causality assumptions undermines the credibility of depression network studies.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Clinical Neurology
Yuri Milaneschi, Matthias Arnold, Gabi Kastenmuller, Siamak Mahmoudian Dehkordi, Ranga R. Krishnan, Boadie W. Dunlop, A. John Rush, Brenda W. J. H. Penninx, Rima Kaddurah-Daouk
Summary: This study found that altered metabolism of acylcarnitines, especially medium-chain acylcarnitines, may be causally linked to increased risk of depression. The findings highlight the potential role of acylcarnitine metabolism in depression pathogenesis and suggest it as a promising target for novel therapeutic approaches.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Oncology
Guang-Li Zhu, Cheng Xu, Kai-Bin Yang, Si-Qi Tang, Ling-Long Tang, Lei Chen, Wen-Fei Li, Yan-Ping Mao, Jun Ma
Summary: This study suggests a causative effect of genetically predicted depression on specific types of cancer, particularly breast cancer. These findings emphasize the importance of depression in the prevention and treatment of breast cancer.
Article
Endocrinology & Metabolism
Yongwei Du, Baohui Xie, Maoyuan Wang, Yanbiao Zhong, Zhimai Lv, Yun Luo, Qiwei He, Zhen Liu
Summary: This study, using MR analysis, demonstrated that testosterone mediates the causal effect of 25(OH)D on osteoporosis. Therefore, interventions targeting testosterone have the potential to substantially reduce the burden of osteoporosis attributable to high 25(OH)D.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Geriatrics & Gerontology
Benedikt Kretzler, Hans-Helmut Koenig, Andre Hajek
Summary: Prior research found that religion had an alleviating effect on depressive symptoms and loneliness. However, it is unclear whether this relationship persisted during the COVID-19 pandemic when worships were mainly held online. This study investigates the link between internet utilization for religious purposes, depressive symptoms, and loneliness during the lockdown period.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Review
Medicine, General & Internal
Helio Jose Coelho-Junior, Riccardo Calvani, Francesco Panza, Riccardo F. Allegri, Anna Picca, Emanuele Marzetti, Vicente Paulo Alves
Summary: The present study found a significant association between religious and spiritual practices and mental health in older adults. Older adults with higher levels of religious and spiritual practices had a lower prevalence of anxiety and depressive symptoms, as well as greater life satisfaction, psychological well-being, better social relations, and more definite meaning in life. The findings were supported by longitudinal studies.
FRONTIERS IN MEDICINE
(2022)
Article
Psychology, Biological
Anika Guha, Cindy M. Yee, Wendy Heller, Gregory A. Miller
Summary: Individuals with a history of depression exhibited greater overall network activation, stronger directed connectivity from DMN to SAL, and worse task performance during positive-word trials. This pattern was not observed among healthy comparison participants.
Article
Clinical Neurology
F. S. Wicke, M. Ernst, D. Otten, A. Werner, M. Dreier, E. Braehler, A. N. Tibubos, I Reiner, M. Michal, J. Wiltink, T. Muenzel, K. J. Lackner, N. Pfeiffer, J. Koenig, P. S. Wild, M. E. Beutel
Summary: The study found that depression increases mortality, but the effect is attenuated after adjusting for social status, physical health, and lifestyle variables. Gender does not significantly influence the relationship between depression and mortality.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychology, Multidisciplinary
Huang Lin, Shujuan Xiao, Lei Shi, Xiao Zheng, Yaqing Xue, Qilong Yun, Ping Ouyang, Dong Wang, Hong Zhu, Chichen Zhang
Summary: The study found that multimorbidity is significantly positively associated with depression, anxiety, and stress symptoms in older adults, especially in females. Therefore, promoting access to multimorbidity treatment for older adults of different sexes may effectively promote mental health in China.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Clinical Neurology
Koichiro Shiba, Adel Daoud, Shiho Kino, Daisuke Nishi, Katsunori Kondo, Ichiro Kawachi
Summary: Understanding the differential mental health effects of traumatic experiences is crucial for identifying vulnerable subpopulations. This study found considerable heterogeneity in the association between disaster-related traumatic experiences and subsequent mental health problems. Some subgroups experienced severe impacts, with the most vulnerable group tending to be from lower socioeconomic backgrounds with preexisting depressive symptoms.
PSYCHIATRY AND CLINICAL NEUROSCIENCES
(2022)
Article
Public, Environmental & Occupational Health
Noah T. Kreski, Qixuan Chen, Mark Olfson, Magdalena Cerda, Deborah Hasin, Silvia S. Martins, Katherine M. Keyes
Summary: Research has shown that changing religious beliefs and service attendance may contribute to the increased depressive symptoms among US adolescents in the past decade, with consistency between the importance of religion and participation potentially reducing the risk of depressive symptoms. The study estimates that maintaining religious factors at 1991 levels could lower depressive symptom trends by 28.2%.
JOURNAL OF RELIGION & HEALTH
(2022)
Article
Psychology, Clinical
M. Vinberg, M. K. Wium-Andersen, I. K. Wium-Andersen, M. B. Jorgensen, K. Christensen, M. Osler
Summary: The study showed that opposite-sex male twins had a slightly higher risk of depression compared to same-sex male twins, while there was a slightly higher but not statistically significant risk for opposite-sex female twins. The findings provided limited support for the hypothesis that prenatal exposure to testosterone was associated with the risk of depression later in life.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Psychiatry
David H. Rosmarin, Caroline C. Kaufman, Stephanie Friree Ford, Poorvi Keshava, Mia Drury, Sean Minns, Cheri Marmarosh, Avijit Chowdhury, Matthew D. Sacchet
Summary: This study systematically reviewed and evaluated studies concurrently examining spirituality/religion (S/R), mental health, and neurobiology. The findings highlight the need for additional research in this area, including validated assessment of S/R.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Genetics & Heredity
Jinyun Chen, Ting Xu, Min Wu
Summary: Observational studies have found an increased incidence of depression in patients with systemic lupus erythematosus (SLE). However, this study using Mendelian randomization analysis showed that there is no genetic relationship between SLE and depression, suggesting that the increased depression in SLE patients is not caused by inheritable risk factors.
FRONTIERS IN GENETICS
(2022)
Article
Psychiatry
Younga H. Lee, Sara Cherkerzian, Larry J. Seidman, George D. Papandonatos, David A. Savitz, Ming T. Tsuang, Jill M. Goldstein, Stephen L. Buka
AMERICAN JOURNAL OF PSYCHIATRY
(2020)
Article
Emergency Medicine
Michael Yang, R. David Hayward, Elango Edhayan
Summary: This study shows that cardiovascular comorbidities are associated with higher risk of negative outcomes among patients hospitalized due to traumatic injury. Pulmonary circulation disorders have the greatest impact, while hypertension has the smallest impact on outcomes.
EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
(2021)
Article
Substance Abuse
Edmund Grady, R. David Hayward, Elango Edhayan
SUBSTANCE USE & MISUSE
(2020)
Article
Public, Environmental & Occupational Health
Stephen L. Buka, Mitch T. Wallin, William J. Culpepper, Younga H. Lee, Ruth Ann Marrie, Lorene M. Nelson, Wendy E. Kaye, Laurie Wagner, Helen Tremlett, Jon Campbell, Nicholas LaRocca
Article
Public, Environmental & Occupational Health
Younga H. Lee, George D. Papandonatos, David A. Savitz, William C. Heindel, Stephen L. Buka
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2020)
Article
Psychiatry
Cristina A. Fernandez, Karmel W. Choi, Brandon D. L. Marshall, Benjamin Vicente, Sandra Saldivia, Robert Kohn, Karestan C. Koenen, Kristopher L. Arheart, Stephen L. Buka
BRITISH JOURNAL OF PSYCHIATRY
(2020)
Article
Environmental Sciences
Marcia P. Jimenez, Gregory A. Wellenius, Peter James, S. V. Subramanian, Stephen Buka, Charles Eaton, Stephen E. Gilman, Eric B. Loucks
ENVIRONMENTAL RESEARCH
(2020)
Article
Psychiatry
Jennifer Brady, R. David Hayward, Elango Edhayan
Summary: This study found that patients with psychiatric disorders require longer treatment and incur higher costs, while mortality rates are only higher for patients with neurological disorders. Identifying patients' psychiatric comorbidities upon admission for trauma may help optimize treatment and reduce the cost of trauma care.
INTERNATIONAL JOURNAL OF PSYCHIATRY IN MEDICINE
(2022)
Article
Surgery
John J. Kanitra, Alexandra D. Power, R. David Hayward, Jimmy C. Haouilou, Elango Edhayan
Summary: Locking temporary hemodialysis catheters (THDC) with heparin is associated with a lower malfunction rate. Increased venous thromboembolism (VTE) prophylaxis may improve THDC patency. Higher D-dimer levels are significantly related to greater mortality but not significantly associated with THDC malfunction.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Peripheral Vascular Disease
John J. Kanitra, Rebekah L. Bjorklund, David J. Clausen, R. David Hayward, Renee A. Paxton, Jimmy C. Haouilou
Summary: This study evaluated the experience of intraoperative heparin reversal with protamine in TCAR. The results showed a near 1:1 ratio of protamine to heparin dose for heparin reversal during TCAR, with similar postoperative bleeding complications compared to the literature. However, patients who received a lower protamine/heparin ratio did not experience bleeding complications. A larger-scale study is needed to evaluate the impact of a lower protamine dose on postoperative complications, especially in the era of protamine shortages.
Article
Psychology
Hannah L. Shields, Kyoko Konishi, Sarah Aroner, Harlyn Aizley, Anne Remington, Hang Lee, Stephen Buka, Jill M. Goldstein
Summary: The study aimed to investigate the impact of sex differences in the timing of hypertension onset on midlife risk for cognitive decline, as well as whether sex-dependent advantages seen in normotensive populations are influenced by the presence of hypertension. Results showed that hypertension in midlife is associated with worse attention and memory performance, with the specific cognitive domains impacted varying by sex. Sex differences observed in normotensive adults' midlife cognitive performance were attenuated in those with hypertension.
JOURNAL OF NEUROPSYCHOLOGY
(2023)
Article
Medicine, General & Internal
John J. Kanitra, Isabella A. Graham, Richard D. Hayward, Darla K. Granger, Richard A. Berg, Jimmy C. Haouilou
Summary: This study compared the estimated cost profiles of TCAR, TF-CAS, and CEA, revealing that hospital reimbursement and profit margins are higher for TF-CAS than for TCAR. Furthermore, with evidence showing similar outcomes with TF-CAS and CEA, further research is needed to examine the long-term cost-effectiveness of TCAR and its comparison to TF-CAS.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Family Studies
Hannah N. Ziobrowski, Stephen L. Buka, S. Bryn Austin, Adam J. Sullivan, Nicholas J. Horton, Melissa Simone, Alison E. Field
CHILD ABUSE & NEGLECT
(2020)
Article
Psychology, Clinical
Amy L. Non, Jorge Carlos Roman, Elizabeth S. Clausing, Stephen E. Gilman, Eric B. Loucks, Stephen L. Buka, Allison A. Appleton, Laura D. Kubzansky
INTERNATIONAL JOURNAL OF BEHAVIORAL MEDICINE
(2020)
Article
Psychiatry
Dana M. Allswede, Robert H. Yolken, Stephen L. Buka, Tyrone D. Cannon