Article
Marine & Freshwater Biology
Andrew Barrick, Olivier Laroche, Michael Boundy, John K. Pearman, Tanja Wiles, Juliette Butler, Xavier Pochon, Kirsty F. Smith, Louis A. Tremblay
Summary: This study analyzed the molecular expression pathways of marine copepod Gladioferens pectinatus exposed to copper, benzophenone, and diclofenac across multiple generations. The results showed that these contaminants altered pathways linked to stress, growth, cellular and metabolic processes. Genes associated with oxidative stress and xenobiotic regulation were also impacted.
AQUATIC TOXICOLOGY
(2022)
Article
Mathematics
Marta Ramos Gonzalez, Antonio Partal Urena, Pilar Gomez Fernandez-Aguado
Summary: The Basel Accord introduced capital requirements for a transnational regulatory framework, with additional regulatory developments on risk measurement in documents by the European Banking Authority and European Central Bank. Focus on credit risk estimation and calibration, particularly for Advanced Internal-Ratings Based models, including defaulted assets. Proposed methodology calibrated on Spanish financial institutions' mortgage portfolios for risk profile comparison, leading to economic analysis of the results.
Article
Chemistry, Multidisciplinary
Shu-Ling Sie, Surabhi Kamal, Zong-Zhan Lu, Ling-Fang Wei, Tzuoo-Tsair Luo, Yen-Hsiang Liu, Chao-Wan Chang, Kai-Ming Chi, Kuang-Lieh Lu
Summary: The chemistry of mixed-valence coordination polymers and metal-organic frameworks is of great interest due to their limited numbers and intriguing properties. However, the scarcity of these compounds can be attributed to the lack of effective synthesis methods. In this study, a novel Cu-I/Cu-II mixed-valence coordination polymer was successfully synthesized and characterized. This research provides an important example for the design, synthesis, and crystal engineering of mixed-valence compounds.
Article
Pharmacology & Pharmacy
Sara Wengschick, Marius Hittinger, Katharina Rotermund, Ralf-Kilian Zah, Jessica Gillmann, Daniel Primavessy
Summary: In this technical note, an easy to use method for determining mucoadhesion for ophthalmica is presented, which can be easily applied in a regulated setting. The method is designed to test two formulations against each other and provide information on bioequivalence. Testing 14 different commercially available ocular formulations, it was found that formulations with higher contents of hyaluronic acid tend to have higher mucoadhesion.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2022)
Article
Chemistry, Multidisciplinary
Mengying Li, Xin Liu, Yan Che, Hongzhu Xing, Fanfei Sun, Wei Zhou, Guangshan Zhu
Summary: We developed a method of controlled partial linker thermolysis to introduce desirable mesopores into mono-ligand MOFs, which is different from the classical thermolyzing method. After the treatment, UiO-66-NH2 shows significant mesoporosity, retained crystal structure, improved charge photogeneration, and abundant anchoring sites, ideal for single-site photocatalysis. Atomically dispersed Cu is then accommodated in the tailored pore, enabling excellent performance for photocatalytic alkylation and oxidation coupling.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Yang-Hua Li, Xin-Ying Wang, Yu-Qi Liu, Si-Yu Dai, Nan-Hao Jin, Han Chen, Xiao-Ming Liu, Yue Zhao, Hui-Long Luo, Wei Li
Summary: Two multifunctional Cu(II) coordination complexes were successfully synthesized using a solvothermal method, showing excellent catalytic activity towards oxygen evolution reaction and photocatalytic degradation of methyl orange under sunlight irradiation. The use of mixed ligands is a promising approach to obtain multifunctional complexes with high efficiency, low cost, and environmental friendliness.
Article
Chemistry, Multidisciplinary
Han Zhang, Yu Yang, Yongxiang Liang, Jun Li, An Zhang, Han Zheng, Zhigang Geng, Fengwang Li, Jie Zeng
Summary: This study demonstrates the preparation of Cu clusters through an electrochemical method, showing excellent performance in methane selectivity. High-resolution microscopy and in situ spectroscopic analyses confirm the distinctive CH4 selectivity due to the sub-nanometer size of the clusters and the stabilization by residual ligands of MOF.
Review
Oncology
Zhe Wang, Dekui Jin, Shuaishuai Zhou, Niujing Dong, Yuting Ji, Peng An, Jiaping Wang, Yongting Luo, Junjie Luo
Summary: Copper is an essential micronutrient that plays a vital role in various biological processes, and any dysregulation of copper metabolism can lead to diseases such as copper overload and deficiency. Cancer, with its high mortality rates, is closely connected to copper, as elevated levels of copper can be found in cancer tissue. Copper also affects tumor progression by influencing angiogenesis and metastasis. Cuproptosis, a novel form of cell death, provides potential targeting strategies for cancer therapy. Copper chelators and copper ionophores are two compounds used for the treatment of cancer. This review aims to explore the relationship between copper metabolism and cancer, and clarify the role of copper metabolism and cuproptosis in targeted cancer therapy.
FRONTIERS IN ONCOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Marzieh Tahmasbi, Nadiya Koukabi, Farzad Seidi
Summary: In this study, a novel and recoverable nickel-based metal-organic framework catalyst was successfully fabricated for carbon-carbon bond formation in organic chemistry. The catalyst exhibited an efficient magnetic core-shell structure and a 3D dendritic fibrous morphology, with excellent thermal stability and magnetic properties. Moreover, the catalyst showed high performance in synthesizing diphenylacetylene under solvent-free and microwave conditions.
Article
Chemistry, Analytical
Xue Hu, Xiaodan Zhang, Haiyan Cao, Yuming Huang
Summary: A new strategy was developed to modulate the emission of copper nanoclusters by ZIF-8 encapsulation, leading to the appearance of a new blue emission peak and an increased quantum yield. This approach also demonstrated potential for sensitive detection of toxic Ag+ ions, expanding the applications of CuNCs.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Haoze Wang, Zhaolin Shi, Jingjing Yang, Tu Sun, Bunyarat Rungtaweevoranit, Hao Lyu, Yue-Biao Zhang, Omar M. Yaghi
Summary: In this study, a metal docking strategy was introduced using the spatial arrangement of organic struts in a MOF. The resulting metalated MOFs showed high capacity and selectivity for Xe adsorption, with Ag-MOF-303 exhibiting exceptional performance. Coordination geometries of Cu-I and Ag-I were examined using advanced spectroscopy techniques.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Physical
Nishesh Kumar Gupta, Jiyeol Bae, Kwang-Soo Kim
Summary: Bimetallic solutions play a crucial role in the growth and functionality of copper trimesate metal-organic frameworks. The presence of Ag+ affects the morphology and surface properties of the MOF, while divalent cations deteriorate its properties. Furthermore, unconventional Cu+ in the MOF forms a new building unit, confirmed in all MOFs. Except for Ag and Mn, no other MOFs show the presence of secondary cations. While Ag-Cu-BTC exhibits improved H2S uptake capacity, other M-Cu-BTC MOFs have superior organic pollutant adsorption behavior.
Article
Chemistry, Multidisciplinary
Jinxian Cui, Yaomei Fu, Jian Song, Bo Meng, Jie Zhou, Ziyan Zhou, Zhongmin Su
Summary: The application of solar energy for converting CO2 into valuable chemicals and fuels is a desirable approach to address the greenhouse effect and energy crisis. However, finding suitable photocatalysts remains a major challenge. This study demonstrates the potential of Cu-I cluster-based covalent metal-organic frameworks (CMOFs) as efficient photocatalysts for CO2 reduction, achieving high production rates of HCOOH and CO. In situ DRIFTS and DFT calculations provide insights into the active center, reaction intermediates, and product generation pathways.
Article
Chemistry, Physical
Ju-E Cun, Xi Fan, Qingqing Pan, Wenxia Gao, Kui Luo, Bin He, Yuji Pu
Summary: This article reviews the applications of copper-based metal-organic frameworks (Cu-MOFs) in the field of biomedicine and discusses their future development prospects. The article introduces the synthesis methods and strategies of Cu-MOFs and summarizes their recent advances in cancer treatment, bacterial inhibition, biosensing, biocatalysis, and wound healing.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2022)
Review
Environmental Sciences
Abigail Erinc, Melinda B. Davis, Vasantha Padmanabhan, Elizabeth Langen, Jaclyn M. Goodrich
Summary: Studies suggest that PFAS may be risk factors for HDP, showing associations, but more research is needed to further understand this link.
ENVIRONMENTAL RESEARCH
(2021)