Article
Chemistry, Applied
Ilbilge Oguz, Halil Ibrahim Oguz, Nesibe Ebru Kafkas
Summary: The study compared the fruits of different Lycium barbarum genotypes and Lycium chinense genotype harvested at various ripening stages based on pomological properties and chemical compounds. Results showed that M1 ALTUNI genotype had the highest sugar contents. Succinic acid was found to be the most abundant acid in all goji berry genotypes.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Article
Agronomy
Woo-Suk Jung, Ill-Min Chung, Seung-Hyun Kim, Hee-Yeon Chi, Chang Yeon Yu, Bimal Kumar Ghimire
Summary: An efficient in vitro direct shoot regeneration system was established for Lycium chinense Miller using leaf explants, where factors influencing the regeneration process were studied to optimize the culture conditions. The use of MS medium supplemented with lower concentrations of BAP and TDZ was found to increase shoot regeneration frequency, while IBA was more effective for root system regeneration and growth. The genetic stability between the regenerated shoots and donor plants was confirmed through ISSR analysis, suggesting the potential of this system for mass propagation and genetic improvement in L. chinense.
Article
Nutrition & Dietetics
Mi-Ra Oh, Su-Jin Jung, Soo-Wan Chae, Byung-Hyun Park, Seung-Ok Lee
Summary: This study found that Lycium chinense Miller fruit extract (LFE) has hepatoprotective effects on subjects with mild hepatic dysfunction and no possible side effects.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Food Science & Technology
Chan Hum Park, Min Jo Kim, Yun Jeong Ji, Jin Pyeong Jeon, Takako Yokozawa
Summary: The study demonstrated that Lycii Fructus extract is beneficial in ameliorating renal injury induced by cisplatin, with effects including mitigating weight loss, reducing kidney weight, lowering serum creatinine levels, decreasing oxidative stress and inflammation markers, and attenuating histological damage in the kidney.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Chemistry, Medicinal
Ya-Di Duan, Cheng-Yuan Su, Yan Liang, Ying-Ying Su, Lin-Lin Zhu, Wei Zhang, Bin Liu
Summary: Four new diastereoisomeric neolignan glycosides (1-4) and nine known lignan glycosides (5-13) were isolated from the root bark of Lycium chinense Mill. Their structures and absolute configurations were determined using NMR spectroscopy, ECD, Mo-2(OAc)(4)-induced ECD spectra, enzymatic hydrolysis, and acid hydrolysis. The isolated compounds were evaluated for their inhibitory activity against alpha-glucosidase, and compounds 8 and 13 showed moderate inhibitory activities with IC50 values of 26.82 +/- 2.71 and 43.14 +/- 2.81 μg/mL, respectively.
Article
Plant Sciences
Feng Qiao, Kaimin Zhang, Lianyu Zhou, Quan-Sheng Qiu, Zhenning Chen, Yueheng Lu, Luhao Wang, Guigong Geng, Huichun Xie
Summary: Lycium chinense is an important medicinal plant in northwest China, and flavonoids are the major pharmacological components of its fruits. The study found that flavonoid content in L. chinense fruits increased with fruit development, and enzymes PAL, CHS, and F3H played important roles in flavonoid accumulation. Transcriptomic and gene expression analyses revealed the key pathways and genes involved in flavonoid metabolism. These findings enhance our understanding of dynamic changes in flavonoids during fruit development and improve the utilization of L. chinense fruits.
JOURNAL OF PLANT PHYSIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Zhipeng Sun, Li Xue, Yun Li, Gaofeng Cui, Ranran Sun, Meiying Hu, Guohua Zhong
Summary: This study found that rotenone can cause necrosis in insect cells through a mitochondrial- and plasmic membrane-dependent pattern, rather than apoptosis.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2021)
Article
Plant Sciences
Ruyu Yao, Michael Heinrich, Xinning Zhao, Qiuling Wang, Jianhe Wei, Peigen Xiao
Summary: Goji berries have been traditionally used for food and medicine for over a millennium, with the fruits of L. barbarum and L. chinense being interchangeably used since at least 682 CE. While L. barbarum is recognized for its superior quality, the more accessible fruits of L. chinense were commonly used as equivalents. Further scientific evidence is needed to ensure the safe and effective use of both species.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Chemistry, Applied
Meimei Xing, Guoyun Li, Yang Liu, Luyao Yang, Youjiao Zhang, Yuruo Zhang, Jianhua Ding, Ming Lu, Guangli Yu, Gang Hu
Summary: Parkinson's disease is a neurodegenerative disease characterized by the loss of dopaminergic neurons. Fucoidan, a marine-origin sulfated polysaccharide enriched in brown algae and sea cucumbers, has emerged as a neuroprotective agent. This study isolated and purified four different fucoidan species and found that Type II fucoidan from Fucus ves-iculosus significantly improved mitochondrial dysfunction and had neuroprotective effects in a PD mouse model.
CARBOHYDRATE POLYMERS
(2023)
Article
Horticulture
Kun Yan, Yibo Zhi, Hongyan Su, Jinxin Cui, Yanan Sun, Suxin Li, Guanyu Zhou
Summary: Photosystem stability and cooperation in halophytic shrub wolfberry were investigated under salt stress. Results showed that wolfberry exhibited high tolerance of photosystems under 200 mM NaCl stress, but suffered significant photoinhibition in both PSII and PSI under 300 mM NaCl stress, with PSI being more severely damaged.
SCIENTIA HORTICULTURAE
(2023)
Review
Biochemistry & Molecular Biology
Hammad Ullah, Alessandro Di Minno, Cristina Santarcangelo, Haroon Khan, Maria Daglia
Summary: Mitochondrial dysfunction leads to cellular defects and neuronal damage, contributing to neurodegenerative disorders. Antioxidants and beta-caryophyllene show potential in stabilizing mitochondria and reducing oxidative stress.
Article
Food Science & Technology
Min Wang, Tianxiong Xu, Li Gao, Chujun Huang, Piao Xu, Congcong Gong, William Kwame Amakye, Linfeng Liao, Maojin Yao, Jiaoyan Ren
Summary: Mitochondrial dysfunction is closely associated with aging and aging-related diseases, such as Alzheimer's disease. It is unclear if different mouse models with mitochondrial-related diseases exhibit similar changes in mitochondrial morphology in the same tissues. Additionally, it is unknown if similarities in mitochondrial morphology can be used as a marker for screening and discovering mitochondrial-protective substances.
FOOD SCIENCE AND HUMAN WELLNESS
(2023)
Article
Horticulture
Lulu Yang, Qiong Liang, Yanjun Zhang, Shuhui Wang, Fang Yuan, Jie Wang
Summary: This study investigated the variation in active compounds and nutrients of L. chinense leaves from different populations in different regions and seasons. Results showed significant differences in functional components among populations, with the SS population having the highest average contents. Certain components showed a correlation with geographic location, and mean annual temperature was the environmental factor most closely correlated with functional components. This study provides valuable information for the quality assessment and breeding of L. chinense germplasm resources.
SCIENTIA HORTICULTURAE
(2021)
Article
Biochemistry & Molecular Biology
Daniela Mendes, Francisco Peixoto, Maria Manuel Oliveira, Paula Branquinho Andrade, Romeu Antonio Videira
Summary: SC-Nanophytosomes, an oral mitochondria-targeted formulation, show significant benefits on brain and skeletal muscle tissues in a rat model of PD. It improves the activity of mitochondrial complexes, mitigates motor disabilities, and counteracts oxidative stress and lipidome changes in the skeletal muscle tissue.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Horticulture
Ilbilge Oguz, Halil Ibrahim Oguz, Ipek Urun, Sule Hilal Attar, Sema Atasever, Nesibe Ebru Kafkas
Summary: With increasing understanding of the health benefits of goji berry, its popularity has rapidly grown worldwide due to continued research and effective marketing strategies. Goji fruit and juice are now marketed as healthy food products in many countries. This study aimed to identify aroma compounds in different ripening periods of goji fruit using GC-MS and SPME fibers, and to compare them with dried fruit. It also aimed to detect protein content in different ripening periods of goji fruit and compare different genotypes. The study found 35 volatile aroma compounds and the highest protein content in the 'M1 ALTUNI' genotype during the green period.
Article
Biochemistry & Molecular Biology
Jun H. Heo, Sang R. Lee, Seong Lae Jo, Hyun Yang, Hye Won Lee, Eui-Ju Hong
Summary: Letrozole, an aromatase inhibitor used in breast cancer treatment, has been reported to cause metabolic changes and structural remodeling in the heart. Our study found that letrozole exposure in female rats resulted in decreased fatty acid oxidation, increased glycolysis, and left ventricular hypertrophy. This shift in cardiac metabolism may lead to reduced energy supply and increased risk of heart failure.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Green & Sustainable Science & Technology
Uttam Kumer Sarker, Md. Salahuddin Kaysar, Md. Romij Uddin, Md. Alamgir Hossain, Sabry Hassan, Mohamed M. Hassan
Summary: Bangladesh is primarily an agricultural country where agriculture in the char areas faces challenges such as climate risks, lack of resources, and underdeveloped markets. By studying cropping patterns and proposing adjustment strategies, solutions can be provided to improve production conditions for local farmers.
Article
Nutrition & Dietetics
Seong-Lae Jo, Hyun Yang, Sang R. Lee, Jun H. Heo, Hye-Won Lee, Eui-Ju Hong
Summary: This study focuses on the relationship between neurodegenerative diseases and energy metabolism, using Curcumae radix extract in cells and animal models. The results show that Curcumae radix can reduce neurodegenerative markers and influence cellular glycolysis and mitochondrial function.
Article
Plant Sciences
Uzzal Somaddar, Hridoy Chandra Dey, Sarah Khanam Mim, Uttam Kumer Sarker, Md Romij Uddin, Nasar Uddin Ahmed, Mohammad Golam Mostofa, Gopal Saha
Summary: Silicon application can improve salt tolerance in rice, especially in salt-sensitive cultivars.
Article
Biology
Md Salahuddin Kaysar, Uttam Kumer Sarker, Sirajam Monira, Md Alamgir Hossain, Md Sabibul Haque, Uzzal Somaddar, Gopal Saha, Apurbo Kumar Chaki, Md Romij Uddin
Summary: Understanding the link between root morphological traits and yields is crucial for improving crop management. In this study, a pot experiment was conducted to evaluate root traits and grain yield performance of 13 rice cultivars. Considerable variations were observed among cultivars in root traits, total dry matter, and grain yield. Cluster analysis and principal component analysis identified promising cultivars with favorable root traits, total dry matter, and yield performance.
Review
Integrative & Complementary Medicine
Sae-Rom Jeon, Jung Won Kang, Lin Ang, Hye Won Lee, Myeong Soo Lee, Tae-Hun Kim
Summary: This article provides an overview of the evidence for complementary and alternative medicines (CAMs) interventions in the treatment of COVID-19 patients. The study found that Traditional Chinese Medicine (TCM) herbal medications showed positive results in reducing disease progression, shortening fever resolution time, and decreasing the risk of severe COVID-19 cases. However, the effectiveness of other interventions still needs further evaluation. Gastric disturbance was a main adverse event of TCM medications.
INTEGRATIVE MEDICINE RESEARCH
(2022)
Article
Environmental Sciences
Md. Salahuddin Kaysar, Uttam Kumer Sarker, Sirajam Monira, Md. Alamgir Hossain, Nadira Mokarroma, Uzzal Somaddar, Gopal Saha, S. S. Farhana Hossain, Apurbo Kumar Chaki, Md. Romij Uddin
Summary: The presence of water or the degree of soil saturation directly affects the root development and function in rice. A pot investigation was conducted to test the response of root traits and yield components of boro rice varieties under different irrigation regimes. The study revealed a decline in root attributes at lower soil saturation levels and observed an increase in root number, length, volume, dry matter, and grain yield under saturated condition.
Article
Chemistry, Medicinal
Chan-young Kim, Hyeong-Geug Kim, Hye Won Lee, In-Chan Seol, Yoon-Sik Kim, Hyung Il Choi, Miso S. Park, Ho-Ryong Yoo
Summary: This study evaluated the pharmacological properties of Jaeumgeonbi-Tang (JGT) in chronic subjective dizziness (CSD) patients. The results showed that JGT can improve redox status and balance psycho-emotional stress hormones, which is beneficial for CSD patients.
Article
Nutrition & Dietetics
Seong-Lae Jo, Hyun Yang, Kang-Joo Jeong, Hye-Won Lee, Eui-Ju Hong
Summary: Inflammation is a natural defense mechanism, but chronic inflammation can lead to various chronic diseases. Neuroinflammation in the central nervous system is important in the development of neurodegenerative diseases. Polyphenol-rich natural products, such as Ecklonia cava, have anti-inflammatory and antioxidant properties and can be used to control neuroinflammation in the treatment of neurodegenerative diseases. In this study, we found that Ecklonia cava extract can reduce the levels of pro-inflammatory cytokines and markers of inflammation and neurodegeneration in mice with chronic inflammation induced by lipopolysaccharide.
Article
Green & Sustainable Science & Technology
Md. Salahuddin Kaysar, Uttam Kumer Sarker, Sirajam Monira, Md. Alamgir Hossain, Uzzal Somaddar, Gopal Saha, Apurbo Kumar Chaki, Abeer Hashem, Elsayed Fathi Abd Allah, Md Romij Uddin
Summary: The relationship between rice root morphology and potassium (K) has a significant impact on the growth and development of rice as well as its yield. In this study conducted at the net house of the Department of Agronomy at the Bangladesh Agricultural University, different rice varieties (Binadhan-10, Hira-2, and BRRI dhan29) were treated with different doses of K fertilizers. The results showed that the dose of 65 kg K ha(-1) significantly improved root traits and yield. However, further increase in K dosage did not lead to an increase in root traits and yield. A positive correlation was observed between yield and all root traits except root porosity. Therefore, a dose of 65 kg K ha(-1) can be recommended for satisfactory yield when cultivating Binadhan-10 at the field level.
Article
Agronomy
Md. Salahuddin Kaysar, Uttam Kumer Sarker, Sinthia Afsana Kheya, Ahmed Khairul Hasan, Md. Alamgir Hossain, Uzzal Somaddar, Gopal Saha, Apurbo Kumar Chaki, Abeer Hashem, Elsayed Fathi Abd-Allah, Md. Romij Uddin
Summary: Irrigation and fertilizer have significant effects on rice root traits and yield. A pot experiment was conducted in the boro season of 2021-2022 to investigate the effects of different irrigation, potassium, and nitrogen conditions on root parameters and yield of the rice variety Binadhan-10. The results showed that the saturation condition with K-65 and N-140 had the best performance in terms of root parameters, and grain yield was highest under this combination. Therefore, Binadhan-10 can be successfully cultivated with K-65 and N-140 under saturation conditions.
Article
Green & Sustainable Science & Technology
Rigyan Gupta, Mohammad Joyel Sarkar, Md. Shafiqul Islam, Md. Romij Uddin, Israt Jahan Riza, Sirajam Monira, Farhana Zaman, Ahmed Khairul Hasan, A. K. M. Mominul Islam, Abeer Hashem, Graciela Dolores Avila-Quezada, Javid A. Parray, Elsayed Fathi Abd Allah, Uttam Kumer Sarker
Summary: In the hill regions of Bangladesh, where cultivable land is limited, efficient land use is necessary to increase crop output. Through a field experiment, incorporating mustard and mungbean into a rice-based cropping pattern was found to significantly improve yield and farmer income. The modified cropping pattern resulted in a higher rice equivalent yield compared to the existing cropping patterns, and the gross margin was significantly higher as well. Mustard and mungbean cultivation in hilly areas can bring quick economic returns and may be introduced on a large scale in Khagrachhari district.
Article
Biochemistry & Molecular Biology
Seong-Lae Jo, Hyun Yang, Hye Won Lee, Eui-Ju Hong
Summary: Endoplasmic reticulum (ER) stress is caused by impaired protein-folding machinery, leading to accumulation of misfolded proteins and triggering unfolded-protein response. Excessive ER stress leads to cell death and chronic disease development. Curcumin regulates ER stress and inflammation, exerting neuroprotective effects. Investigating the effects of curcumin on ER stress, inflammation, and neurodegeneration is therefore important.
Review
Medicine, General & Internal
Hye Won Lee, Lin Ang, Jung Tae Kim, Myeong Soo Lee
Summary: This updated review provides a detailed understanding of the potential application of aromatherapy for relieving pain and anxiety in burn patients. The meta-analyses show that inhaled aromatherapy plus routine care has beneficial effects in relieving pain after dressing and calming anxiety.
MEDICINA-LITHUANIA
(2022)
Review
Andrology
Hye Won Lee, Myeong Soo Lee, Tae-Hun Kim, Terje Alraek, Chris Zaslawski, Jong Wook Kim, Du Geon Moon
Summary: Ginseng has minimal impact on erectile dysfunction, adverse events, and satisfaction, but may improve self-reported sexual performance in men.
WORLD JOURNAL OF MENS HEALTH
(2022)