Dyspnea and Reversibility Profile of P2Y12 Antagonists: Systematic Review of New Antiplatelet Drugs

Characterization of the Adenosine Pharmacology of Ticagrelor Reveals Therapeutically Relevant Inhibition of Equilibrative Nucleoside Transporter 1

(2014) Duncan Armstrong et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Effect of ticagrelor on pulmonary function in healthy elderly volunteers and asthma or chronic obstructive pulmonary disease patients

(2013) Kathleen Butler et al.   CURRENT MEDICAL RESEARCH AND OPINION

Ticagrelor Enhances Adenosine-Induced Coronary Vasodilatory Responses in Humans

(2013) Ann Wittfeldt et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events

(2013) Deepak L. Bhatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized, Double-Blind, Active-Controlled Phase 2 Trial to Evaluate a Novel Selective and Reversible Intravenous and Oral P2Y 12 Inhibitor Elinogrel Versus Clopidogrel in Patients Undergoing Nonurgent Percutaneous Coronary Intervention

(2012) Robert C. Welsh et al.   Circulation-Cardiovascular Interventions

Bridging Antiplatelet Therapy With Cangrelor in Patients Undergoing Cardiac Surgery

(2012) Dominick J. Angiolillo et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Viewpoint: Reversible nature of platelet binding causing transfusion-related acute lung injury (TRALI) syndrome may explain dyspnea after ticagrelor and elinogrel

(2012) Victor Serebruany   THROMBOSIS AND HAEMOSTASIS

Why does ticagrelor induce dyspnea?

(2012) Elena Faioni et al.   THROMBOSIS AND HAEMOSTASIS

Pulmonary Function in Patients With Acute Coronary Syndrome Treated With Ticagrelor or Clopidogrel (from the Platelet Inhibition and Patient Outcomes [PLATO] Pulmonary Function Substudy)

(2011) Robert F. Storey et al.   AMERICAN JOURNAL OF CARDIOLOGY

Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes

(2011) Robert F. Storey et al.   EUROPEAN HEART JOURNAL

Ticagrelor Inhibits Adenosine Uptake In Vitro and Enhances Adenosine-Mediated Hyperemia Responses in a Canine Model

(2011) J. J. J. van Giezen et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

New P2Y 12 Inhibitors

(2010) Marco Cattaneo   CIRCULATION

Response to Ticagrelor in Clopidogrel Nonresponders and Responders and Effect of Switching Therapies

(2010) Paul A. Gurbel et al.   CIRCULATION

Incidence of Dyspnea and Assessment of Cardiac and Pulmonary Function in Patients With Stable Coronary Artery Disease Receiving Ticagrelor, Clopidogrel, or Placebo in the ONSET/OFFSET Study

(2010) Robert F. Storey et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Randomized Double-Blind Assessment of the ONSET and OFFSET of the Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Stable Coronary Artery Disease

(2009) Paul A. Gurbel et al.   CIRCULATION

Identification of the Human Cytochrome P450 Enzymes Involved in the Two Oxidative Steps in the Bioactivation of Clopidogrel to Its Pharmacologically Active Metabolite

(2009) M. Kazui et al.   DRUG METABOLISM AND DISPOSITION

Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes

(2009) Lars Wallentin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Platelet Inhibition with Cangrelor in Patients Undergoing PCI

(2009) Robert A. Harrington et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of Clopidogrel in Patients With Acute Coronary Syndromes Requiring Coronary Artery Bypass Surgery

(2008) Jeffrey S. Berger et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The MRC breathlessness scale

(2008) C. Stenton   OCCUPATIONAL MEDICINE-OXFORD