Gaviscon Double Action Liquid (antacid & alginate) is more effective than antacid in controlling post-prandial oesophageal acid exposure in GERD patients: a double-blind crossover study

Randomised clinical trial: relief of upper gastrointestinal symptoms by an acid pocket-targeting alginate-antacid (Gaviscon Double Action) - a double-blind, placebo-controlled, pilot study in gastro-oesophageal reflux disease

(2014) E. Thomas et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Proton Pump Inhibitors Reduce the Size and Acidity of the Acid Pocket in the Stomach

(2014) Wout O. Rohof et al.   Clinical Gastroenterology and Hepatology

Post-prandial reflux suppression by a raft-forming alginate (Gaviscon Advance) compared to a simple antacid documented by magnetic resonance imaging and pH-impedance monitoring: mechanistic assessment in healthy volunteers and randomised, controlled, doub

(2013) R. Sweis et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The Acid Pocket: A Target for Treatment in Reflux Disease?

(2013) Peter J Kahrilas et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

An Alginate-Antacid Formulation Localizes to the Acid Pocket to Reduce Acid Reflux in Patients With Gastroesophageal Reflux Disease

(2013) Wout O. Rohof et al.   Clinical Gastroenterology and Hepatology

High resolution manometry to detect transient lower oesophageal sphincter relaxations: diagnostic accuracy compared with perfused-sleeve manometry, and the definition of new detection criteria

(2011) S. Roman et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

An alginate-antacid formulation (Gaviscon Double Action Liquid) can eliminate or displace the postprandial ‘acid pocket’ in symptomatic GERD patients

(2011) M. A. Kwiatek et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The position of the acid pocket as a major risk factor for acidic reflux in healthy subjects and patients with GORD

(2009) H. Beaumont et al.   GUT

American Gastroenterological Association Medical Position Statement on the Management of Gastroesophageal Reflux Disease

(2008) Peter J. Kahrilas et al.   GASTROENTEROLOGY

Paradox of gastric cardia: it becomes more acidic following meals while the rest of stomach becomes less acidic

(2008) A T Clarke et al.   GUT