Randomised clinical trial: relief of upper gastrointestinal symptoms by an acid pocket-targeting alginate-antacid (Gaviscon Double Action) - a double-blind, placebo-controlled, pilot study in gastro-oesophageal reflux disease

417 Effect of PPIs on the Size, Position and Acidity of the Postprandial Acid Pocket

(2015) Wout O. Rohof et al.   GASTROENTEROLOGY

Post-prandial reflux suppression by a raft-forming alginate (Gaviscon Advance) compared to a simple antacid documented by magnetic resonance imaging and pH-impedance monitoring: mechanistic assessment in healthy volunteers and randomised, controlled, doub

(2013) R. Sweis et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The Acid Pocket: A Target for Treatment in Reflux Disease?

(2013) Peter J Kahrilas et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

An Alginate-Antacid Formulation Localizes to the Acid Pocket to Reduce Acid Reflux in Patients With Gastroesophageal Reflux Disease

(2013) Wout O. Rohof et al.   Clinical Gastroenterology and Hepatology

Capping the Gastric Acid Pocket to Reduce Postprandial Acid Gastroesophageal Reflux

(2013) Daniel Sifrim et al.   Clinical Gastroenterology and Hepatology

Effect of azithromycin on acid reflux, hiatus hernia and proximal acid pocket in the postprandial period

(2012) W O Rohof et al.   GUT

An alginate-antacid formulation (Gaviscon Double Action Liquid) can eliminate or displace the postprandial ‘acid pocket’ in symptomatic GERD patients

(2011) M. A. Kwiatek et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Overlap of dyspepsia and gastroesophageal reflux in the general population: one disease or distinct entities?

(2011) R. S. Choung et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Physicians and Patients Measure Different Dimension on Assessment for Gastroesophageal Reflux Disease-related Symptoms

(2011) Juan Carlos Lopez-Alvarenga et al.   Journal of Neurogastroenterology and Motility

Relationship between symptom load of gastro-oesophageal reflux disease and health-related quality of life, work productivity, resource utilization and concomitant diseases: survey of a US cohort

(2010) P. WAHLQVIST et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Accuracy of the diagnosis of GORD by questionnaire, physicians and a trial of proton pump inhibitor treatment: the Diamond Study

(2010) J. Dent et al.   GUT

Trends in Gastroesophageal Reflux Disease as Measured by the National Ambulatory Medical Care Survey

(2009) Frank K. Friedenberg et al.   DIGESTIVE DISEASES AND SCIENCES

Alginate–antacid combinations: raft formation and gastric retention studies

(2009) Frank C. Hampson et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

The position of the acid pocket as a major risk factor for acidic reflux in healthy subjects and patients with GORD

(2009) H. Beaumont et al.   GUT

Impact of gastroesophageal reflux disease on work absenteeism, presenteeism and productivity in daily life: a European observational study

(2009) Javier P Gisbert et al.   Health and Quality of Life Outcomes

Relationship Between Symptoms and Dietary Patterns in Patients With Functional Dyspepsia

(2008) Amelia N. Pilichiewicz et al.   Clinical Gastroenterology and Hepatology

Dyspepsia and IBS Symptoms in Patients with NERD, ERD and Barrett’s Esophagus

(2008) Helmut Neumann et al.   DIGESTIVE DISEASES

Paradox of gastric cardia: it becomes more acidic following meals while the rest of stomach becomes less acidic

(2008) A T Clarke et al.   GUT

Severe reflux disease is associated with an enlarged unbuffered proximal gastric acid pocket

(2007) A T Clarke et al.   GUT