Neurokinin-1-receptor antagonism decreases anxiety and emotional arousal circuit response to noxious visceral distension in women with irritable bowel syndrome: a pilot study

What is the value of human FMRI in CNS drug development?

(2010) Richard G. Wise et al.   DRUG DISCOVERY TODAY

A selective neurokinin-1 receptor antagonist in chronic PTSD: A randomized, double-blind, placebo-controlled, proof-of-concept trial

(2010) Sanjay J. Mathew et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla

(2010) S.C. LaGraize et al.   NEUROSCIENCE

Anxiolytic-like effects of the neurokinin 1 receptor antagonist GR-205171 in the elevated plus maze and contextual fear-potentiated startle model of anxiety in gerbils

(2009) Scott A. Heldt et al.   BEHAVIOURAL PHARMACOLOGY

Development of the 2nd generation neurokinin-1 receptor antagonist LY686017 for social anxiety disorder

(2009) Johannes Tauscher et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

T1261 The Effect of Chronic Neurokinin-1 Receptor Antagonism On Sympathetic Nervous System Activity in Irritable Bowel Syndrome (IBS)

(2009) Kirsten Tillisch et al.   GASTROENTEROLOGY

Affective disturbances modulate the neural processing of visceral pain stimuli in irritable bowel syndrome: an fMRI study

(2009) S Elsenbruch et al.   GUT

NK1 receptor antagonism and the neural processing of emotional information in healthy volunteers

(2009) Ciara McCabe et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Sex differences in brain activity during aversive visceral stimulation and its expectation in patients with chronic abdominal pain: A network analysis

(2008) J.S. Labus et al.   NEUROIMAGE

Neurokinin 1 Receptor Antagonism as a Possible Therapy for Alcoholism

(2008) D. T. George et al.   SCIENCE