Peroxisome Proliferator-Activated Receptorsαandγare Linked with Alcohol Consumption in Mice and Withdrawal and Dependence in Humans

PPAR agonists regulate brain gene expression: Relationship to their effects on ethanol consumption

(2014) Laura B. Ferguson et al.   NEUROPHARMACOLOGY

FKBP5 Moderates Alcohol Withdrawal Severity: Human Genetic Association and Functional Validation in Knockout Mice

(2014) Ming-Chyi Huang et al.   NEUROPSYCHOPHARMACOLOGY

Activation of PPARγ by Pioglitazone Potentiates the Effects of Naltrexone on Alcohol Drinking and Relapse in msP Rats

(2013) Serena Stopponi et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

PPAR Agonists as Therapeutics for CNS Trauma and Neurological Diseases

(2013) Shweta Mandrekar-Colucci et al.   ASN Neuro

Social Isolation Exacerbates Schizophrenia-Like Phenotypes via Oxidative Stress in Cortical Interneurons

(2013) Zhihong Jiang et al.   BIOLOGICAL PSYCHIATRY

Peroxisome Proliferator-Activated Receptor (PPAR) Agonists as Promising New Medications for Drug Addiction: Preclinical Evidence

(2013) Bernard Le Foll et al.   CURRENT DRUG TARGETS

Neuroimmune signaling: a key component of alcohol abuse

(2013) Jody Mayfield et al.   CURRENT OPINION IN NEUROBIOLOGY

Gene Expression in Brain and Liver Produced by Three Different Regimens of Alcohol Consumption in Mice: Comparison with Immune Activation

(2013) Elizabeth Osterndorff-Kahanek et al.   PLoS One

A Gut Lipid Messenger Links Excess Dietary Fat to Dopamine Deficiency

(2013) L. A. Tellez et al.   SCIENCE

The PPARα/γAgonist, Tesaglitazar, Improves Insulin Mediated Switching of Tissue Glucose and Free Fatty Acid UtilizationIn Vivoin the Obese Zucker Rat

(2013) Kristina Wallenius et al.   PPAR Research

Gabapentin Treatment for Alcohol Dependence

(2013) Barbara J. Mason et al.   JAMA Internal Medicine

Family-based genome-wide association study of frontal theta oscillations identifies potassium channel gene KCNJ6

(2012) S. J. Kang et al.   GENES BRAIN AND BEHAVIOR

PGC1  and mitochondrial metabolism - emerging concepts and relevance in ageing and neurodegenerative disorders

(2012) S. Austin et al.   JOURNAL OF CELL SCIENCE

Gene Coexpression Networks in Human Brain Identify Epigenetic Modifications in Alcohol Dependence

(2012) I. Ponomarev et al.   JOURNAL OF NEUROSCIENCE

A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53

(2012) J-C Wang et al.   MOLECULAR PSYCHIATRY

Novel Use of a Lipid-Lowering Fibrate Medication to Prevent Nicotine Reward and Relapse: Preclinical Findings

(2012) Leigh V Panlilio et al.   NEUROPSYCHOPHARMACOLOGY

Assessment of Chitosan-Affected Metabolic Response by Peroxisome Proliferator-Activated Receptor Bioluminescent Imaging-Guided Transcriptomic Analysis

(2012) Chia-Hung Kao et al.   PLoS One

Activation of Nuclear PPARγ Receptors by the Antidiabetic Agent Pioglitazone Suppresses Alcohol Drinking and Relapse to Alcohol Seeking

(2011) Serena Stopponi et al.   BIOLOGICAL PSYCHIATRY

Inhibitory kappa B kinases as targets for pharmacological regulation

(2011) Carly Gamble et al.   BRITISH JOURNAL OF PHARMACOLOGY

Peroxisome proliferator-activated receptor-α activation attenuates 3-nitropropionic acid induced behavioral and biochemical alterations in rats: Possible neuroprotective mechanisms

(2011) Deepak Kumar Bhateja et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effects of chronic systemic treatment with peroxisome proliferator-activated receptor α activators on neuroinflammation induced by intracerebral injection of lipopolysaccharide in adult mice

(2011) Guangming Wang et al.   NEUROSCIENCE RESEARCH

Neuroprotective Mechanisms of PPARδ: Modulation of Oxidative Stress and Inflammatory Processes

(2011) Caroline I. Schnegg et al.   PPAR Research

Differing short-term neuroprotective effects of the fibrates fenofibrate and bezafibrate in MPTP and 6-OHDA experimental models of Parkinsonʼs disease

(2010) Alexandre Kreisler et al.   BEHAVIOURAL PHARMACOLOGY

Inhibiting NF-κB activation by small molecules as a therapeutic strategy

(2010) Subash C. Gupta et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Blockade of Nicotine Reward and Reinstatement by Activation of Alpha-Type Peroxisome Proliferator-Activated Receptors

(2010) Paola Mascia et al.   BIOLOGICAL PSYCHIATRY

Fetal alcohol-induced hyperactivity is reversed by treatment with the PPARα agonist fenofibrate in a rat model

(2010) Kévin Marche et al.   PSYCHOPHARMACOLOGY

Positive relationship between dietary fat, ethanol intake, triglycerides, and hypothalamic peptides: counteraction by lipid-lowering drugs

(2009) Jessica R. Barson et al.   ALCOHOL

Peroxisome proliferator-activated receptor translational research and clinical experience

(2009) Wayman Wendell Cheatham   AMERICAN JOURNAL OF CLINICAL NUTRITION

A Generalized Family-Based Association Test for Dichotomous Traits

(2009) Wei-Min Chen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals

(2009) Brian L. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GWAF: an R package for genome-wide association analyses with family data

(2009) Ming-Huei Chen et al.   BIOINFORMATICS

Bezafibrate at Clinically Relevant Doses Decreases Serum/Liver Triglycerides via Down-Regulation of Sterol Regulatory Element-Binding Protein-1c in Mice: A Novel Peroxisome Proliferator-Activated Receptor  -Independent Mechanism

(2009) T. Nakajima et al.   MOLECULAR PHARMACOLOGY

Fat-induced satiety factor oleoylethanolamide enhances memory consolidation

(2009) P. Campolongo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IκB kinase β (IKKβ/IKK2/IKBKB)—A key molecule in signaling to the transcription factor NF-κB

(2008) Johannes A. Schmid et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions

(2008) Yuri A. Blednov et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Novel Roles for the NF- B Signaling Pathway in Regulating Neuronal Function

(2008) M. C. Boersma et al.   Science Signaling