Generation of HIV-1 potent and broad neutralizing antibodies by immunization with postfusion HR1/HR2 complex

A Blueprint for HIV Vaccine Discovery

(2012) Dennis R. Burton et al.   Cell Host & Microbe

Neutralizing Epitopes in the Membrane-Proximal External Region of HIV-1 gp41 Are Influenced by the Transmembrane Domain and the Plasma Membrane

(2012) M. Montero et al.   JOURNAL OF VIROLOGY

Passively Transmitted gp41 Antibodies in Babies Born from HIV-1 Subtype C-Seropositive Women: Correlation between Fine Specificity and Protection

(2012) L. Diomede et al.   JOURNAL OF VIROLOGY

Computational study of bindings of HK20 Fab and D5 Fab to HIV-1 gp41

(2011) Yossa Dwi Hartono et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Broad neutralization coverage of HIV by multiple highly potent antibodies

(2011) Laura M. Walker et al.   NATURE

Moving ahead an HIV vaccine: Use both arms to beat HIV

(2011) Bruce D Walker et al.   NATURE MEDICINE

Isolation of a Human Anti-HIV gp41 Membrane Proximal Region Neutralizing Antibody by Antigen-Specific Single B Cell Sorting

(2011) Lynn Morris et al.   PLoS One

Fab crystallization and preliminary X-ray analysis of NC-1, an anti-HIV-1 antibody that recognizes the six-helix bundle core of gp41

(2010) Lei Jin et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Rational antibody-based HIV-1 vaccine design: current approaches and future directions

(2010) Laura M Walker et al.   CURRENT OPINION IN IMMUNOLOGY

Anti-gp41 Antibodies Cloned from HIV-Infected Patients with Broadly Neutralizing Serologic Activity

(2010) J. Pietzsch et al.   JOURNAL OF VIROLOGY

Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates

(2010) E. Bianchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of HIV-1 gp41 Including Both Fusion Peptide and Membrane Proximal External Regions

(2010) Victor Buzon et al.   PLoS Pathogens

Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41

(2010) Elena Gustchina et al.   PLoS Pathogens

Crystal Structure and Size-Dependent Neutralization Properties of HK20, a Human Monoclonal Antibody Binding to the Highly Conserved Heptad Repeat 1 of gp41

(2010) Charles Sabin et al.   PLoS Pathogens

Mode of interaction between the HIV-1-neutralizing monoclonal antibody 2F5 and its epitope

(2009) Uwe Fiebig et al.   AIDS

International Network for Comparison of HIV Neutralization Assays: The NeutNet Report

(2009) Eva Maria Fenyö et al.   PLoS One

Antibodies purified from sera of HIV-1-infected patients by affinity on the heptad repeat region 1/heptad repeat region 2 complex of gp41 neutralize HIV-1 primary isolates

(2008) Nadine Vincent et al.   AIDS

Antigp41 antibodies fail to block early events of virological synapses but inhibit HIV spread between T cells

(2008) Marta Massanella et al.   AIDS

Viral membrane fusion

(2008) Stephen C Harrison   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies

(2008) G. Frey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics

(2008) Josh D. Nelson et al.   VIROLOGY