IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice

Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice

(2013) Connie Jackaman et al.   AGING CELL

Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

(2013) Myriam N. Bouchlaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blood CD33(+)HLA-DR(−) myeloid-derived suppressor cells are increased with age and a history of cancer

(2013) Chris P. Verschoor et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Chemotherapy broadens the range of tumor antigens seen by cytotoxic CD8+ T cells in vivo

(2012) Connie Jackaman et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Rejuvenation of Regeneration in the Aging Central Nervous System

(2012) Julia M. Ruckh et al.   Cell Stem Cell

IL-2/CD40-driven NK cells install and maintain potency in the anti-mesothelioma effector/memory phase

(2012) Connie Jackaman et al.   INTERNATIONAL IMMUNOLOGY

Aging Enhances the Production of Reactive Oxygen Species and Bactericidal Activity in Peritoneal Macrophages by Upregulating Classical Activation Pathways

(2011) Heather S. Smallwood et al.   BIOCHEMISTRY

Circulating and tumor-infiltrating myeloid cells predict survival in human pleural mesothelioma

(2011) Bryan M. Burt et al.   CANCER

Intratumoral interleukin-2/agonist CD40 antibody drives CD4+-independent resolution of treated-tumors and CD4+-dependent systemic and memory responses

(2011) Connie Jackaman et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Advanced Age Impairs Macrophage Polarization

(2011) Shegufta Mahbub et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Monocyte Chemoattractant Protein–1 Blockade Inhibits Lung Cancer Tumor Growth by Altering Macrophage Phenotype and Activating CD8+Cells

(2010) Zvi G. Fridlender et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Potential role of immunosenescence in cancer development

(2010) Tamas Fulop et al.   Annals of the New York Academy of Sciences

Cytokine-armed vaccinia virus infects the mesothelioma tumor microenvironment to overcome immune tolerance and mediate tumor resolution

(2010) C Jackaman et al.   CANCER GENE THERAPY

In Aged Mice, Outgrowth of Intraocular Melanoma Depends on Proangiogenic M2-Type Macrophages

(2010) L. V. Ly et al.   JOURNAL OF IMMUNOLOGY

Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels

(2009) Rong Yuan et al.   AGING CELL

Delayed but excellent myogenic stem cell response of regenerating geriatric skeletal muscles in mice

(2009) Thea Shavlakadze et al.   BIOGERONTOLOGY

Effects of aging on T cell function

(2009) Laura Haynes et al.   CURRENT OPINION IN IMMUNOLOGY

Antigen-specific Treg impair CD8+T-cell priming by blocking early T-cell expansion

(2009) Pascal Chappert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Local effector failure in mesothelioma is not mediated by CD4+ CD25+ T-regulator cells

(2009) C. Jackaman et al.   EUROPEAN RESPIRATORY JOURNAL

Deliberately provoking local inflammation drives tumors to become their own protective vaccine site

(2008) Connie Jackaman et al.   INTERNATIONAL IMMUNOLOGY

Designing ageing conditions in tumour microenvironment—A new possible modality for cancer treatment

(2008) Judith Leibovici et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Effect of Senescence on Macrophage Polarization and Angiogenesis

(2008) Dru S. Dace et al.   REJUVENATION RESEARCH