Genomics of human health and aging

Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan

(2011) Alexander M. Kulminski et al.   AGING CELL

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

(2011) Joris Deelen et al.   AGING CELL

Complex phenotypes and phenomenon of genome-wide inter-chromosomal linkage disequilibrium in the human genome

(2011) Alexander M. Kulminski   EXPERIMENTAL GERONTOLOGY

Life at the Extreme Limit: Phenotypic Characteristics of Supercentenarians in Okinawa

(2011) D. C. Willcox et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

A Prospective Study of High-Density Lipoprotein Cholesterol, Cholesteryl Ester Transfer Protein Gene Variants, and Healthy Aging in Very Old Japanese-American Men

(2011) T. A. Koropatnick et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Contemporary human genetic strategies in aging research

(2010) Cinnamon S. Bloss et al.   AGEING RESEARCH REVIEWS

Protein homeostasis and aging: The importance of exquisite quality control

(2010) Hiroshi Koga et al.   AGEING RESEARCH REVIEWS

Genetic Heterogeneity in Human Disease

(2010) Jon McClellan et al.   CELL

Genetics of Hypertension and Cardiovascular Disease and Their Interconnected Pathways: Lessons from Large Studies

(2010) Aldi T. Kraja et al.   CURRENT HYPERTENSION REPORTS

A Network Perspective on Metabolism and Aging

(2010) Q. A. Soltow et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Genetic Studies Reveal the Role of the Endocrine and Metabolic Systems in Aging

(2010) Nir Barzilai et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The pursuit of genome-wide association studies: where are we now?

(2010) Chee Seng Ku et al.   JOURNAL OF HUMAN GENETICS

A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

(2010) Anne B. Newman et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Beta2-adrenergic receptor gene polymorphisms as systemic determinants of healthy aging in an evolutionary context

(2010) Alexander M. Kulminski et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Xmrks the spot: life history tradeoffs, sexual selection and the evolutionary ecology of oncogenesis

(2010) KYLE SUMMERS et al.   MOLECULAR ECOLOGY

Biodemography of human ageing

(2010) James W. Vaupel   NATURE

Neural mechanisms of ageing and cognitive decline

(2010) Nicholas A. Bishop et al.   NATURE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Genomics of human longevity

(2010) P. E. Slagboom et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Systems biology of ageing and longevity

(2010) T. B. L. Kirkwood   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Selection on Alleles Affecting Human Longevity and Late-Life Disease: The Example of Apolipoprotein E

(2010) Fotios Drenos et al.   PLoS One

Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity

(2010) M. Beekman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Signatures of Exceptional Longevity in Humans

(2010) P. Sebastiani et al.   SCIENCE

Prospects for Life Span Extension

(2009) Felipe Sierra et al.   Annual Review of Medicine

Changing course in ageing research: The Healthy Ageing Phenotype

(2009) Oscar H. Franco et al.   MATURITAS

Genome-wide association study identifies eight loci associated with blood pressure

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Genome-wide association study of blood pressure and hypertension

(2009) Daniel Levy et al.   NATURE GENETICS

Human genetic variation and its contribution to complex traits

(2009) Kelly A. Frazer et al.   NATURE REVIEWS GENETICS

Common disorders are quantitative traits

(2009) Robert Plomin et al.   NATURE REVIEWS GENETICS

Decanalization and the origin of complex disease

(2009) Greg Gibson   NATURE REVIEWS GENETICS

Common Genetic Variation and Human Traits

(2009) David B. Goldstein   NEW ENGLAND JOURNAL OF MEDICINE

Evolution of the human lifespan and diseases of aging: Roles of infection, inflammation, and nutrition

(2009) C. E. Finch   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association ofFOXO3Avariation with human longevity confirmed in German centenarians

(2009) Friederike Flachsbart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding cardiovascular disease through the lens of genome-wide association studies

(2009) Dan E. Arking et al.   TRENDS IN GENETICS

Shifting Paradigm of Association Studies: Value of Rare Single-Nucleotide Polymorphisms

(2008) Ivan P. Gorlov et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Different Types of Cell Death in Organismal Aging and Longevity: State of the Art and Possible Systems Biology Approach

(2008) Claudio Franceschi et al.   CURRENT PHARMACEUTICAL DESIGN

Signaling networks in aging

(2008) Eric L. Greer et al.   JOURNAL OF CELL SCIENCE

A HapMap harvest of insights into the genetics of common disease

(2008) Teri A. Manolio et al.   JOURNAL OF CLINICAL INVESTIGATION

Common variants at 30 loci contribute to polygenic dyslipidemia

(2008) Sekar Kathiresan et al.   NATURE GENETICS

FOXO3A genotype is strongly associated with human longevity

(2008) B. J. Willcox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA