Regulatory B Cells Inhibit Cytotoxic T Lymphocyte (CTL) Activity and Elimination of Infected CD4 T Cells after In Vitro Reactivation of HIV Latent Reservoirs

IgG4 production is confined to human IL-10–producing regulatory B cells that suppress antigen-specific immune responses

(2013) Willem van de Veen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8+ T cell function in vitro

(2013) Basile Siewe et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Combined approaches for HIV cure

(2013) David M. Margolis et al.   Current Opinion in HIV and AIDS

Do HIV-specific CTL continue to have an antiviral function during antiretroviral therapy? If not, why not, and what can be done about it?

(2013) Dorian McIlroy   Frontiers in Immunology

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

Small Molecules and Big Killers: The Challenge of Eliminating the Latent HIV Reservoir

(2012) Stephen A. Migueles et al.   IMMUNITY

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

(2012) Liang Shan et al.   IMMUNITY

IL-10-Producing Regulatory B Cells in the Pathogenesis of Chronic Hepatitis B Virus Infection

(2012) A. Das et al.   JOURNAL OF IMMUNOLOGY

In Vivo Blockade of the PD-1 Receptor Suppresses HIV-1 Viral Loads and Improves CD4+ T Cell Levels in Humanized Mice

(2012) B. E. Palmer et al.   JOURNAL OF IMMUNOLOGY

Direct in vivo evidence of CD4+ T cell requirement for CTL response and memory via pMHC-I targeting and CD40L signaling

(2012) Khawaja Ashfaque Ahmed et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

(2012) N. M. Archin et al.   NATURE

A new dynamic model of three cell interactions for CTL responses

(2012) Khawaja Ashfaque Ahmed et al.   OncoImmunology

Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression

(2011) A. R. Hersperger et al.   BLOOD

Maturation and function of human dendritic cells are regulated by B lymphocytes

(2011) A. Morva et al.   BLOOD

Qualitative features of the HIV-specific CD8+ T-cell response associated with immunologic control

(2011) Adam R Hersperger et al.   Current Opinion in HIV and AIDS

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

IL-10 produced by activated human B cells regulates CD4+ T-cell activation in vitro

(2010) Jean-David Bouaziz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory B Cells (B10 Cells) and Regulatory T Cells Have Independent Roles in Controlling Experimental Autoimmune Encephalomyelitis Initiation and Late-Phase Immunopathogenesis

(2010) T. Matsushita et al.   JOURNAL OF IMMUNOLOGY

Programmed death-1–induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection

(2010) Elias A Said et al.   NATURE MEDICINE

Expression of Latent HIV Induced by the Potent HDAC Inhibitor Suberoylanilide Hydroxamic Acid

(2009) Nancie M. Archin et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells

(2009) M. A. Brockman et al.   BLOOD

Suberoylanilide Hydroxamic Acid Reactivates HIV from Latently Infected Cells

(2009) Xavier Contreras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhancing SIV-specific immunity in vivo by PD-1 blockade

(2008) Vijayakumar Velu et al.   NATURE

IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection

(2008) D. G. Brooks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA