Transition-Metal-Free Regioselective Alkylation of Quinoline N-Oxides via Oxidative Alkyl Migration and C−C Bond Cleavage of tert-/sec-Alcohols

Lewis Acid Catalyzed Dehydrogenative Coupling of Tertiary Propargylic Alcohols with Quinoline N-Oxides

(2017) Ya-Ping Han et al.   JOURNAL OF ORGANIC CHEMISTRY

Development and Mechanistic Study of Quinoline-Directed Acyl C–O Bond Activation and Alkene Oxyacylation Reactions

(2017) Giang T. Hoang et al.   JOURNAL OF ORGANIC CHEMISTRY

Visible-Light-Induced C2 Alkylation of Pyridine N-Oxides

(2017) Wen-Man Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

The photochemical alkylation and reduction of heteroarenes

(2017) T. McCallum et al.   Chemical Science

Simple and Clean Photo-induced Methylation of Heteroarenes with MeOH

(2017) Wenbo Liu et al.   Chem

Transition-Metal-Free Regioselective Alkylation of Pyridine N -Oxides Using 1,1-Diborylalkanes as Alkylating Reagents

(2016) Woohyun Jo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The microwave-assisted ortho-alkylation of azine N-oxides with N-tosylhydrazones catalyzed by copper(i) iodide

(2016) Abadh Kishor Jha et al.   CHEMICAL COMMUNICATIONS

Benzylation of heterocyclic N-oxides via direct oxidative cross-dehydrogenative coupling with toluene derivatives

(2016) L. Wan et al.   NEW JOURNAL OF CHEMISTRY

C2-Alkenylation of N-heteroaromatic compounds via Brønsted acid catalysis

(2016) Giacomo E. M. Crisenza et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of 2-Alkenylquinoline by Reductive Olefination of Quinoline N-Oxide under Metal-Free Conditions

(2016) Hong Xia et al.   ORGANIC LETTERS

Regio- and Stereoselective Alkylation of Pyridine-N-oxides: Synthesis of Substituted Piperidines and Pyridines

(2016) Deepak Kumar Barange et al.   ORGANIC LETTERS

Catalytic C–C Bond Activations via Oxidative Addition to Transition Metals

(2015) Laetitia Souillart et al.   CHEMICAL REVIEWS

Heterocyclic N-Oxides - An Emerging Class of Therapeutic Agents

(2015) A.M. Mfuh et al.   CURRENT MEDICINAL CHEMISTRY

Pyridine N-Oxide vs Pyridine Substrates for Rh(III)-Catalyzed Oxidative C–H Bond Functionalization

(2015) Sharon R. Neufeldt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-free methylation of a pyridine N-oxide C–H bond by using peroxides

(2015) Gang Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Regioselective Metal-Free Cross-Coupling of Quinoline N-Oxides with Boronic Acids

(2015) Luis Bering et al.   ORGANIC LETTERS

Palladium-Catalyzed Regioselective Benzylation–Annulation of Pyridine N-Oxides with Toluene Derivatives via Multiple C–H Bond Activations: Benzylation versus Arylation

(2015) Ebrahim Kianmehr et al.   ORGANIC LETTERS

Direct, Catalytic, and Regioselective Synthesis of 2-Alkyl-, Aryl-, and Alkenyl-Substituted N-Heterocycles from N-Oxides

(2014) Oleg V. Larionov et al.   ORGANIC LETTERS

Direct C-2 Alkylation of QuinolineN-Oxides with EthersviaPalladium-Catalyzed Dehydrogenative Cross-Coupling Reaction

(2013) Zhiyong Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Asymmetrically Substituted Terpyridines by Palladium-Catalyzed Direct CH Arylation of PyridineN-Oxides

(2013) Sasa Duric et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rh(III)-Catalyzed C–H Activation and Double Directing Group Strategy for the Regioselective Synthesis of Naphthyridinones

(2013) John R. Huckins et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed C–H Activation/Cross-Coupling of Pyridine N-Oxides with Nonactivated Secondary Alkyl Bromides

(2013) Bin Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Oxidative CH/CH Direct Coupling of Heterocyclic N-Oxides

(2013) Wei Liu et al.   ORGANIC LETTERS

A Versatile Rhodium(I) Catalyst System for the Addition of Heteroarenes to both Alkenes and Alkynes by a CH Bond Activation

(2012) Jaeyune Ryu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic Studies on Direct Arylation of Pyridine N-Oxide: Evidence for Cooperative Catalysis between Two Distinct Palladium Centers

(2012) Yichen Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Palladium-Catalyzed Oxidative Cross-Coupling between PyridineN-Oxides and Indoles

(2011) Xue Gong et al.   ORGANIC LETTERS

Facile One-Pot Direct Arylation and Alkylation of NitropyridineN-Oxides with Grignard Reagents

(2011) Fang Zhang et al.   ORGANIC LETTERS

Efficient, mild and completely regioselective synthesis of substituted pyridines

(2010) Hans Andersson et al.   CHEMICAL COMMUNICATIONS

An Expedient Procedure for the Oxidative Cleavage of Olefinic Bonds with PhI(OAc)2, NMO, and Catalytic OsO4

(2010) K. C. Nicolaou et al.   ORGANIC LETTERS

Palladium-Catalyzed Direct Arylation of Azine and AzoleN-Oxides: Reaction Development, Scope and Applications in Synthesis

(2009) Louis-Charles Campeau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Alkenylation of Quinoline-N-oxides via C−H Activation under External-Oxidant-Free Conditions

(2009) Junliang Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Coupling of Nitrogen Heteroaromatics and Alkanes without Transition Metals: A New Oxidative Cross-Coupling at CH/CH Bonds

(2008) Guojun Deng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed C−H Functionalization of PyridineN-Oxides: Highly Selective Alkenylation and Direct Arylation with Unactivated Arenes

(2008) Seung Hwan Cho et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY