Ene Reductase-Catalysed Synthesis of (R)-Profen Derivatives

Chemoenzymatic One-Pot Synthesis of γ-Butyrolactones

(2011) Margarete Korpak et al.   ADVANCED SYNTHESIS & CATALYSIS

A Site-Saturated Mutagenesis Study of Pentaerythritol Tetranitrate Reductase Reveals that Residues 181 and 184 Influence Ligand Binding, Stereochemistry and Reactivity

(2011) Helen S. Toogood et al.   CHEMBIOCHEM

Combination of CC Bond Formation by Wittig Reaction and Enzymatic CC Bond Reduction in a One-Pot Process in Water

(2011) Marina Kraußer et al.   ChemCatChem

Biocatalytic strategies for the asymmetric synthesis of profens – recent trends and developments

(2011) Robert Kourist et al.   GREEN CHEMISTRY

Lipase-catalyzed alcoholytic resolution of (R,S)-flurbiprofenyl azolides for preparation of (R)-NO-flurbiprofen ester prodrugs

(2011) Jyun-Fen Ciou et al.   PROCESS BIOCHEMISTRY

Asymmetric Synthesis of (R)-3-Hydroxy-2-methylpropanoate (‘Roche Ester’) and Derivatives via Biocatalytic CC-Bond Reduction

(2010) Clemens Stueckler et al.   ADVANCED SYNTHESIS & CATALYSIS

Biocatalytic Reductions and Chemical Versatility of the Old Yellow Enzyme Family of Flavoprotein Oxidoreductases

(2010) Helen S. Toogood et al.   ChemCatChem

Directed Evolution of an Enantioselective Lipase with Broad Substrate Scope for Hydrolysis of α-Substituted Esters

(2010) Karin Engström et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iterative Saturation Mutagenesis Accelerates Laboratory Evolution of Enzyme Stereoselectivity: Rigorous Comparison with Traditional Methods

(2010) Manfred T. Reetz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An effective kinetic resolution of racemic α-arylpropanoic acids, α-arylbutanoic acids, and β-substituted-α-arylpropanoic acids with bis(9-phenanthryl)methanol as a new achiral nucleophile in the asymmetric esterification using carboxylic anhydrides and the acyl-transfer catalyst

(2010) Kenya Nakata et al.   TETRAHEDRON LETTERS

Site-selective Suzuki-Miyaura reactions of the bis(triflate) of 1,3-dihydroxyanthraquinone

(2010) Omer A. Akrawi et al.   TETRAHEDRON LETTERS

Directed Evolution of an Enantioselective Enoate-Reductase: Testing the Utility of Iterative Saturation Mutagenesis

(2009) Despina J. Bougioukou et al.   ADVANCED SYNTHESIS & CATALYSIS

Biocatalysis with Thermostable Enzymes: Structure and Properties of a Thermophilic ‘ene’-Reductase related to Old Yellow Enzyme

(2009) Björn V. Adalbjörnsson et al.   CHEMBIOCHEM

Improvements of enzyme activity and enantioselectivity in lipase-catalyzed alcoholysis of (R,S)-azolides

(2009) An-Chi Wu et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Asymmetric Bioreduction of CC Bonds using Enoate Reductases OPR1, OPR3 and YqjM: Enzyme-Based Stereocontrol

(2008) Mélanie Hall et al.   ADVANCED SYNTHESIS & CATALYSIS

Structure-Based Insight into the Asymmetric Bioreduction of the CC Double Bond of α,β-Unsaturated Nitroalkenes by Pentaerythritol Tetranitrate Reductase

(2008) Helen S. Toogood et al.   ADVANCED SYNTHESIS & CATALYSIS

Prediction and Manipulation of the Stereochemistry of Enoylreduction in Modular Polyketide Synthases

(2008) David H. Kwan et al.   CHEMISTRY & BIOLOGY

Asymmetric Bioreduction of Activated C=C Bonds UsingZymomonas mobilis NCR Enoate Reductase and Old Yellow Enzymes OYE 1–3 from Yeasts

(2008) Mélanie Hall et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Product identification and distribution from the oscillatory versus non-oscillatory palladium(II) iodide-catalysed oxidative carbonylation of phenylacetylene

(2008) Christophe Grosjean et al.   JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL

Highly Enantioselective Reduction of β,β-Disubstituted Aromatic Nitroalkenes Catalyzed byClostridium sporogenes

(2008) Anna Fryszkowska et al.   JOURNAL OF ORGANIC CHEMISTRY