The DIONESUS algorithm provides scalable and accurate reconstruction of dynamic phosphoproteomic networks to reveal new drug targets

The re-emergence of natural products for drug discovery in the genomics era

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A Systems Approach to Integrative Biology: An Overview of Statistical Methods to Elucidate Association and Architecture

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Enhanced Prediction of Src Homology 2 (SH2) Domain Binding Potentials Using a Fluorescence Polarization-derived c-Met, c-Kit, ErbB, and Androgen Receptor Interactome

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Clinical Approval Success Rates for Investigational Cancer Drugs

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Metrics other than potency reveal systematic variation in responses to cancer drugs

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p38 MAP kinase enhances EGF-induced apoptosis in A431 carcinoma cells by promoting tyrosine phosphorylation of STAT1

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TIGRESS: Trustful Inference of Gene REgulation using Stability Selection

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Caffeic Acid Phenethyl Ester Suppresses the Proliferation of Human Prostate Cancer Cells through Inhibition of p70S6K and Akt Signaling Networks

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Wisdom of crowds for robust gene network inference

(2012) Daniel Marbach et al.   NATURE METHODS

GeneNetWeaver: in silico benchmark generation and performance profiling of network inference methods

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Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits

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Targeted protein-omic methods are bridging the gap between proteomic and hypothesis-driven protein analysis approaches

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NADPH-oxidase-dependent reactive oxygen species mediate EGFR transactivation by FPRL1 in WKYMVm-stimulated human lung cancer cells

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Effect of complementary pathway blockade on efficacy of combination enzastaurin and rapamycin

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Essential Gene Profiles in Breast, Pancreatic, and Ovarian Cancer Cells

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Receptor Tyrosine Kinase Coactivation Networks in Cancer

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Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation

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Systems analysis of EGF receptor signaling dynamics with microwestern arrays

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Towards a Rigorous Assessment of Systems Biology Models: The DREAM3 Challenges

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Inferring Regulatory Networks from Expression Data Using Tree-Based Methods

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Generating Realistic In Silico Gene Networks for Performance Assessment of Reverse Engineering Methods

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Apoptosis induced by diallyl disulfide in human breast cancer cell line MCF-71

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Synchrony and entrainment properties of robust circadian oscillators

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Learning biological networks: from modules to dynamics

(2008) Richard Bonneau   Nature Chemical Biology

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology