Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells

Cytoskeletal forces during signaling activation in Jurkat T-cells

(2015) King Lam Hui et al.   MOLECULAR BIOLOGY OF THE CELL

Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway

(2015) Sudha Kumari et al.   eLife

T Cell-Dendritic Cell Immunological Synapses Contain TCR-dependent CD28-CD80 Clusters That Recruit Protein Kinase C 

(2014) S.-Y. Tseng et al.   JOURNAL OF IMMUNOLOGY

Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse

(2014) Kaushik Choudhuri et al.   NATURE

Appreciating force and shape — the rise of mechanotransduction in cell biology

(2014) Thomas Iskratsch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CD28 and CD3 have complementary roles in T-cell traction forces

(2014) Keenan T. Bashour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T cell antigen receptor activation and actin cytoskeleton remodeling

(2013) Sudha Kumari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

FHOD1 Is Needed for Directed Forces and Adhesion Maturation during Cell Spreading and Migration

(2013) Thomas Iskratsch et al.   DEVELOPMENTAL CELL

Unique ζ-chain motifs mediate a direct TCR-actin linkage critical for immunological synapse formation and T-cell activation

(2013) Yair Klieger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers

(2013) A. Schonichen et al.   JOURNAL OF CELL SCIENCE

Discrimination of α-Amino Acids Using Green Tea Flavonoid (−)-Epigallocatechin Gallate as a Chiral Solvating Agent

(2013) Divya Kumari et al.   JOURNAL OF ORGANIC CHEMISTRY

Fabrication of three-dimensional electrical connections by means of directed actin self-organization

(2013) Rémi Galland et al.   NATURE MATERIALS

Mechanosensing in T Lymphocyte Activation

(2012) Edward Judokusumo et al.   BIOPHYSICAL JOURNAL

F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation

(2012) Alexander Babich et al.   JOURNAL OF CELL BIOLOGY

Finding the weakest link – exploring integrin-mediated mechanical molecular pathways

(2012) Pere Roca-Cusachs et al.   JOURNAL OF CELL SCIENCE

Substrate Rigidity Regulates Human T Cell Activation and Proliferation

(2012) R. S. O'Connor et al.   JOURNAL OF IMMUNOLOGY

Netrin-1 Attracts Axons through FAK-Dependent Mechanotransduction

(2012) S. W. Moore et al.   JOURNAL OF NEUROSCIENCE

Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells

(2012) Jason Yi et al.   MOLECULAR BIOLOGY OF THE CELL

Ligand Mobility Modulates Immunological Synapse Formation and T Cell Activation

(2012) Chih-Jung Hsu et al.   PLoS One

Development of Polydimethylsiloxane Substrates with Tunable Elastic Modulus to Study Cell Mechanobiology in Muscle and Nerve

(2012) Rachelle N. Palchesko et al.   PLoS One

Cells test substrate rigidity by local contractions on submicrometer pillars

(2012) S. Ghassemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simplified Equation to Extract Diffusion Coefficients from Confocal FRAP Data

(2012) Minchul Kang et al.   TRAFFIC

T Cell Receptor Internalization from the Immunological Synapse Is Mediated by TC21 and RhoG GTPase-Dependent Phagocytosis

(2011) Nuria Martínez-Martín et al.   IMMUNITY

Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension

(2011) Tai Kiuchi et al.   JOURNAL OF CELL BIOLOGY

Force Generation upon T Cell Receptor Engagement

(2011) Julien Husson et al.   PLoS One

Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance

(2010) Thomas Iskratsch et al.   JOURNAL OF CELL BIOLOGY

Cutting Edge: Mechanical Forces Acting on T Cells Immobilized via the TCR Complex Can Trigger TCR Signaling

(2010) Y. C. Li et al.   JOURNAL OF IMMUNOLOGY

Calyculin A-induced neurite retraction is critically dependent on actomyosin activation but not on polymerization state of microtubules

(2009) Ayumu Inutsuka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The αβ T Cell Receptor Is an Anisotropic Mechanosensor

(2009) Sun Taek Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T cell antigen receptor signaling and immunological synapse stability require myosin IIA

(2009) Tal Ilani et al.   NATURE IMMUNOLOGY

Traction on Immobilized Netrin-1 Is Sufficient to Reorient Axons

(2009) S. W. Moore et al.   SCIENCE

Hunter to Gatherer and Back: Immunological Synapses and Kinapses as Variations on the Theme of Amoeboid Locomotion

(2008) Michael L. Dustin   Annual Review of Cell and Developmental Biology

Intercellular Adhesion Molecule-1-Dependent Stable Interactions between T Cells and Dendritic Cells Determine CD8+ T Cell Memory

(2008) Alix Scholer et al.   IMMUNITY

Fabrication of elastomer pillar arrays with modulated stiffness for cellular force measurements

(2008) S. Ghassemi et al.   JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B

Micropatterning of costimulatory ligands enhances CD4+ T cell function

(2008) K. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA