Exercise training, genetics and type 2 diabetes-related phenotypes

Do genetic variations alter the effects of exercise training on cardiovascular disease and can we identify the candidate variants now or in the future?

(2011) James M. Hagberg   JOURNAL OF APPLIED PHYSIOLOGY

The Association Between the Peroxisome Proliferator-Activated Receptor-γ2 (PPARG2) Pro12Ala Gene Variant and Type 2 Diabetes Mellitus: A HuGE Review and Meta-Analysis

(2010) Hebe N. Gouda et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Evidence for an autosomal recessive gene regulating the persistence of the insulin response to glucose in man

(2010) L. Iselius et al.   CLINICAL GENETICS

Significance of genetic factors for the plasma insulin response to glucose in healthy subjects

(2010) Jan Lindsten et al.   CLINICAL GENETICS

Detailed Physiologic Characterization Reveals Diverse Mechanisms for Novel Genetic Loci Regulating Glucose and Insulin Metabolism in Humans

(2010) E. Ingelsson et al.   DIABETES

Common Variants in 40 Genes Assessed for Diabetes Incidence and Response to Metformin and Lifestyle Intervention in the Diabetes Prevention Program

(2010) K. A. Jablonski et al.   DIABETES

Advances in Exercise, Fitness, and Performance Genomics

(2010) TUOMO RANKINEN et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Previously Associated Type 2 Diabetes Variants May Interact With Physical Activity to Modify the Risk of Impaired Glucose Regulation and Type 2 Diabetes: A Study of 16,003 Swedish Adults

(2009) E. C. Brito et al.   DIABETES

Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study

(2009) S.-M. Ruchat et al.   DIABETOLOGIA

Association of angiotensin-converting enzyme insertion/deletion polymorphism with obesity, cardiovascular risk factors and exercise-mediated changes in Korean women

(2009) Kijin Kim   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Gene expression of PPARγ and PGC-1α in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training

(2009) Karen Ruschke et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Endurance exercise training effects on body fatness, V̇o2max, HDL-C subfractions, and glucose tolerance are influenced by a PLIN haplotype in older Caucasians

(2009) Nathan T. Jenkins et al.   JOURNAL OF APPLIED PHYSIOLOGY

SNPs in PPARG Associate with Type 2 Diabetes and Interact with Physical Activity

(2009) TUOMAS O. KILPELÄINEN et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

The Pro12Ala polymorphism of the PPARγ2 gene is associated with hepatic glucose uptake during hyperinsulinemia in subjects with type 2 diabetes mellitus

(2009) Miikka-Juhani Honka et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Alterations in peroxisome proliferator-activated receptor mRNA expression in skeletal muscle after acute and repeated bouts of exercise

(2009) Espen E. Spangenburg et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Human genetics illuminates the paths to metabolic disease

(2009) Stephen O’Rahilly   NATURE

Treatment of Obese Adolescents: The Influence of Periodization Models and ACE Genotype

(2009) Denis Foschini et al.   Obesity

Variations inPPARDDetermine the Change in Body Composition during Lifestyle Intervention: A Whole-Body Magnetic Resonance Study

(2008) Claus Thamer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Human Gene Map for Performance and Health-Related Fitness Phenotypes

(2008) MOLLY S. BRAY et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Genotype Score in Addition to Common Risk Factors for Prediction of Type 2 Diabetes

(2008) James B. Meigs et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes

(2008) Valeriya Lyssenko et al.   NEW ENGLAND JOURNAL OF MEDICINE