Article
Biochemistry & Molecular Biology
Aneta Sporna-Kucab, Anna Tekieli, Agnieszka Grzegorczyk, Lukasz Swiatek, Barbara Rajtar, Krystyna Skalicka-Wozniak, Karolina Starzak, Boris Nemzer, Zbigniew Pietrzkowski, Slawomir Wybraniec
Summary: The study evaluated the correlation between bioactivity and phytochemical profile of betalain-rich extracts from Portulaca grandiflora. The extracts showed antioxidant and antimicrobial activities, with betacyanins demonstrating stronger antibacterial effects.
Article
Engineering, Environmental
Jordi Palatsi, Ferran Ripoll, Albert Benzal, Maite Pijuan, Maycoll Stiven Romero-Guiza
Summary: This paper presents the results of upgrading a full-scale WWTP using five different Advanced Process Control strategies over a seven-year period, which led to significant improvements in nutrient removal rates, energy efficiency, and economic feasibility. The implementation of APC resulted in enhanced nitrogen and phosphorus removal rates, reduced specific energy ratio, and economic benefits in the form of a relatively short return on capital expenses.
Review
Chemistry, Applied
Azucena Rodriguez-Mena, Luz Araceli Ochoa-Martinez, Silvia Marina Gonzalez-Herrera, Olga Miriam Rutiaga-Quinones, Ruben Francisco Gonzalez-Laredo, Begona Olmedilla-Alonso
Summary: This article discusses the latest technologies and applications of plant-derived pigments such as carotenoids, anthocyanins, and betalains. Advanced extraction and encapsulation techniques improve the efficiency of pigment utilization in food, making it more attractive. The application of natural pigments provides health benefits and reduces the risk of various diseases.
Article
Chemistry, Applied
Mara Montiel-Sanchez, Tomas Garcia-Cayuela, Andrea Gomez-Maqueo, Hugo S. Garcia, M. Pilar Cano
Summary: Cactus berry is a scarcely studied Mexican wild fruit with bioactive compounds that demonstrate antioxidant, anti-hyperglycemic, and anti-inflammatory activities. The fruit contains a variety of metabolites, with Phyllocactin and Isorhamnetin rhamnosyl-rutinoside being the most abundant. Studies suggest that cactus berry could be a promising candidate for a sustainable healthy diet.
Editorial Material
Plant Sciences
Hazem S. Elshafie
Summary: This article summarizes the chemical composition and biological-pharmaceutical activities of plant essential oils (PEOs), and discusses their possible modes of action and influencing factors. It provides valuable insights into the application of PEOs.
Review
Chemistry, Applied
Shauna Heffernan, Linda Giblin, Nora O'Brien
Summary: The paper reviews the production of protein hydrolysates from fish muscle, primarily through enzymatic hydrolysis, and their potential bioactivities including anti-obesity, immunomodulatory, antioxidant, ACE-inhibitory, antimicrobial, and anti-cancer properties. Small molecular weight FPHs demonstrate higher bioactivity due to increased absorption through the gastrointestinal tract. The relationship between amino acid composition and sequence of FPH and peptides and their in vitro bioactivity is also discussed.
Article
Biochemistry & Molecular Biology
Agnieszka Szewczyk, Andreana Marino, Maria Fernanda Taviano, Lucia Cambria, Federica Davi, Monika Trepa, Mariusz Grabowski, Natalizia Miceli
Summary: This study evaluated the effects of cultivation time and different concentrations of plant growth regulators on the biomass and secondary metabolite accumulation of R. montana. The major secondary metabolites in R. montana cultures were coumarins, with xanthotoxin and bergapten as the dominant compounds. The extract obtained from the biomass grown on the 0.1/0.1 LS medium showed the best antioxidant activity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biotechnology & Applied Microbiology
Seedhabadee Ganeshan, Seon Hwa Kim, Vladimir Vujanovic
Summary: The benefits of microorganisms in various organisms are increasingly recognized, particularly in sustainable crop production and minimizing the use of chemical fertilizers and pesticides. The challenge for researchers lies in scaling up production, particularly for academia and start-up companies. This review focuses on the fermentation process and manufacturing steps, providing examples of plant endophytes production and highlighting the challenges and future perspectives of scaling up microbial endophyte production technology.
BIORESOURCES AND BIOPROCESSING
(2021)
Editorial Material
Plant Sciences
Hazem S. Elshafie, Ippolito Camele
Summary: Essential oils, derived from plants, are concentrated liquids containing bioactive chemicals and volatile substances. They have been used in folk medicine for their antibacterial properties and have potential applications in the food and cosmetics industries. This Special Issue provides in-depth research on different plant essential oils and their chemical constituents and pharmaceutical functions.
Article
Biotechnology & Applied Microbiology
Lillibeth Chaverra-Munoz, Stephan Huettel
Summary: This study successfully transferred the production process of illudin M from shake flasks to stirred tank bioreactors by controlling key process parameters and achieved a high concentration comparable to that in shake flasks. This is of great significance for achieving a sustainable supply of illudin M and supporting preclinical and clinical development programs.
MICROBIAL CELL FACTORIES
(2022)
Article
Energy & Fuels
Guoqing Hu, Fengqi You
Summary: The advancement of controlled-environment agriculture, particularly in plant factories, offers an innovative solution to address the rising demand for food due to global population growth and urbanization. However, the intensive energy requirements of these systems have raised sustainability concerns. This study introduces a novel cyber-physical-biological system (CPBS) that accurately captures plant biological dynamics and optimizes energy usage and resource expenses in plant factories. The CPBS leverages physics-informed deep learning (PIDL) techniques to develop efficient digital twins for control, leading to improved accuracy and decision-making.
Article
Biotechnology & Applied Microbiology
Magda A. El-Bendary, Mariam E. Fawzy, Mohamed Abdelraof, Mervat El-Sedik, Mousa A. Allam
Summary: This study investigates the decolorization and degradation of malachite green dye using Pseudomonas plecoglossicide MG2 and demonstrates its potential as an efficient, renewable, eco-friendly, and cost-effective tool for the treatment of dye wastewater effluent.
MICROBIAL CELL FACTORIES
(2023)
Article
Energy & Fuels
Hajer Mkacher, Fares AlMomani, Ajinkya Pal, Iftekhar A. Karimi, Easa Al-musleh
Summary: This study presents a rigorous simulation method for the cold section of an LNG plant and proposes a process optimization technique using upfront nitrogen removal. The results show that this technique can significantly increase plant capacity without the need for structural modifications.
INTERNATIONAL JOURNAL OF ENERGY RESEARCH
(2022)
Review
Biochemistry & Molecular Biology
Maria Celeste Dias, Diana C. G. A. Pinto, Artur M. S. Silva
Summary: Flavonoids are natural antioxidants synthesized in plants, playing a crucial role in plant stress tolerance and human health with anti-inflammatory and antimicrobial properties. They also have various applications in the food industry, cosmetics, and pharmaceuticals. Developing extraction methods for flavonoids with high purity and yield is essential for their industrial use.
Article
Biochemical Research Methods
Claudia Amabile, Teresa Abate, Carmen De Crescenzo, Simona Sabbarese, Antimo Migliaccio, Simeone Chianese, Dino Musmarra
Summary: This work presents an innovative process for producing poly(3-hydroxybutyrate) by replacing expensive substrates with methane. The effects of the gas velocity on the mass transfer and production yields were evaluated, and different scenarios were analyzed to optimize the reactor's geometry and methane utilization. The findings suggest that improving the reactor design and methane utilization can increase the overall yield, while changing the aspect ratio may decrease the proportion of poly(3-hydroxybutyrate) in the biomass.
Review
Biochemistry & Molecular Biology
Vasil Georgiev, Ivan Ivanov, Atanas Pavlov
Review
Biotechnology & Applied Microbiology
Gergana Krasteva, Vasil Georgiev, Atanas Pavlov
Summary: Plant cell culture technology has the potential to provide sustainable supply of plant ingredients, addressing global challenges such as climate change and growing energy demands. The technology is applied in the production of plant-derived substances for food and cosmetic formulations, reducing resource consumption and promoting sustainable development. Overcoming challenges in commercialization is crucial for accelerating the mass commercialization and popularization of plant cell culture technology.
ENGINEERING IN LIFE SCIENCES
(2021)
Article
Plant Sciences
Radka Vrancheva, Ivan Ivanov, Ivayla Dincheva, Ilian Badjakov, Atanas Pavlov
Summary: The study identified and quantified triterpenoids and other non-polar compounds in blueberry leaves using GC-MS and HPLC-DAD. Results showed significant differences in metabolite profiles among different Vaccinium species and populations, likely influenced by climatic and geographical conditions.
Article
Multidisciplinary Sciences
Radka Vrancheva, Ivayla Dincheva, Ina Aneva, Vasil Georgiev, Atanas Pavlov
Summary: The study found that in vitro S. montana plants have abundant primary and secondary metabolites with pharmacological and biological activities beneficial to humans. Therefore, in vitro cultivated S. montana plants have the potential to be a matrix for the production of valuable biologically active substances for the food, pharmaceutical, and cosmetic industries.
COMPTES RENDUS DE L ACADEMIE BULGARE DES SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Tsvetelina Andonova, Yordan Muhovski, Radka Vrancheva, Ilya Slavov, Elena Apostolova, Samir Naimov, Atanas Pavlov, Ivanka Dimitrova-Dyulgerova
Summary: Interest in plant extracts as a natural source of antioxidants has increased in recent years. The ethanol extracts from aerial parts of Koelreuteria paniculata were analyzed for their flavonoids and phenolic acids content, as well as their antioxidant and DNA-protective activity. The extracts showed significant in vitro antioxidant activity, with the highest activity detected in the flower parts. This study also provided the first report on the DNA-protective capacity of the extracts and the diagnostic microscopic features of the plant.
Article
Biochemistry & Molecular Biology
Gergana Krasteva, Strahil Berkov, Atanas Pavlov, Vasil Georgiev
Summary: This study analyzed the metabolite profiles, antioxidant activities, and genetic variations of Gardenia jasminoides in vitro cultures. The results showed correlations between antioxidant activity and the concentrations of certain compounds. The in vitro cultures of Gardenia jasminoides exhibited high genetic variabilities.
Article
Chemistry, Multidisciplinary
Alexandra Garmidolova, Ivelina Desseva, Dasha Mihaylova, Hafize Fidan, Margarita Terziyska, Atanas Pavlov
Summary: The enzymatic hydrolysis of lupin proteins showed potential health benefits such as antioxidant and acetylcholinesterase inhibitory activities, making them a promising source of bioactive peptides.
APPLIED SCIENCES-BASEL
(2022)
Article
Plant Sciences
Tsvetelina Andonova, Yordan Muhovski, Iliya Slavov, Radka Vrancheva, Vasil Georgiev, Elena Apostolova, Samir Naimov, Rumen Mladenov, Atanas Pavlov, Ivanka Dimitrova-Dyulgerova
Summary: This study analyzed the main phenolic compounds in the flowers, leaves, and stem bark of Ailanthus altissima and determined their DNA-protective and antioxidant potential. The highest antioxidant activity was found in the flower parts, followed by the leaves. This research demonstrates that A. altissima could be a natural source of DNA protection and antioxidants.
Article
Chemistry, Multidisciplinary
Gergana Krasteva, Tsvetanka Teneva-Angelova, Ilian Badjakov, Ivayla Dincheva, Vasil Georgiev, Atanas Pavlov
Summary: Cultivation of plant cells under controlled conditions is an effective technique for producing antioxidants. Research has shown that using illumination leads to higher phenolics, anthocyanins, and antioxidant activities. Additionally, culturing in darkness results in higher accumulation of dry biomass and exopolysaccharides production.
APPLIED SCIENCES-BASEL
(2023)
Article
Multidisciplinary Sciences
Radka Vrancheva, Ivan Ivanov, Ilian Badjakov, Ivayla Dincheva, Vasil Georgiev, Atanas Pavlov
Summary: Bilberries, known for their high content of polyphenolic compounds, have been traditionally used in folk medicine and have shown strong antioxidant properties with potential preventive and therapeutic effects for various diseases. Recent studies have shown that bilberry leaves, containing compounds similar to those in the fruits, can be considered as an alternative source of bioactive substances. The research revealed significant intrapopulation variations in bilberry, especially in terms of the quantity of investigated secondary metabolites.
COMPTES RENDUS DE L ACADEMIE BULGARE DES SCIENCES
(2021)
Article
Plant Sciences
Jorge Juan-Vicedo, Atanas Pavlov, Segundo Rios, Jose Luis Casas
Summary: The study aimed to investigate the in vitro propagation of bulb scale explants from five endemic, rare and/or endangered Narcissus species from the Iberian Peninsula, treated with different PGR combinations. The results showed successful initiation, multiplication, and rooting processes, with high bulblet proliferation and acclimatization rates.
ACTA BIOLOGICA CRACOVIENSIA SERIES BOTANICA
(2021)