P300-dependent STAT3 acetylation is necessary for angiotensin II-induced pro-fibrotic responses in renal tubular epithelial cells

Curcumin Triggers p16-Dependent Senescence in Active Breast Cancer-Associated Fibroblasts and Suppresses Their Paracrine Procarcinogenic Effects

(2015) Siti-Fauziah Hendrayani et al.   NEOPLASIA

Inhibition of STAT3 acetylation is associated with attenuated renal fibrosis in the obstructed kidney

(2014) Jun Ni et al.   ACTA PHARMACOLOGICA SINICA

Cyclovirobuxinum D suppresses lipopolysaccharide-induced inflammatory responses in murine macrophages in vitro by blocking JAK-STAT signaling pathway

(2014) Dan Guo et al.   ACTA PHARMACOLOGICA SINICA

Involvement of Nuclear JAK2 Signaling in AG490-Induced Apoptosis of Gastric Cancer Cells

(2014) Cuijuan Qian et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

(2014) Gautam Sethi et al.   Molecular Cancer

Apocynin attenuates oxidative stress and cardiac fibrosis in angiotensin II-induced cardiac diastolic dysfunction in mice

(2013) Yu-qiong Li et al.   ACTA PHARMACOLOGICA SINICA

Selective Inhibition of p300 HAT Blocks Cell Cycle Progression, Induces Cellular Senescence, and Inhibits the DNA Damage Response in Melanoma Cells

(2013) Gai Yan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A Histone Acetyltransferase p300 Inhibitor C646 Induces Cell Cycle Arrest and Apoptosis Selectively in AML1-ETO-Positive AML Cells

(2013) Xiao-ning Gao et al.   PLoS One

SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-κB/STAT3 complex to its promoter in malignant lymphoid cells

(2013) A Scuto et al.   Cell Death & Disease

The biphasic redox sensing of SENP3 accounts for the HIF-1 transcriptional activity shift by oxidative stress

(2012) Ying Wang et al.   ACTA PHARMACOLOGICA SINICA

Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation

(2012) Dong-bo Liu et al.   ACTA PHARMACOLOGICA SINICA

The effects of curcumin post-treatment against myocardial ischemia and reperfusion by activation of the JAK2/STAT3 signaling pathway

(2012) Weixun Duan et al.   BASIC RESEARCH IN CARDIOLOGY

Auto-acetylation stabilizes p300 in cardiac myocytes during acute oxidative stress, promoting STAT3 accumulation and cell survival

(2012) Sumit Jain et al.   BREAST CANCER RESEARCH AND TREATMENT

Genetic or Pharmacologic Blockade of EGFR Inhibits Renal Fibrosis

(2012) N. Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The pathogenic role of the renal proximal tubular cell in diabetic nephropathy

(2012) S. C. W. Tang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

A Natural p300-Specific Histone Acetyltransferase Inhibitor, Curcumin, in Addition to Angiotensin-Converting Enzyme Inhibitor, Exerts Beneficial Effects on Left Ventricular Systolic Function After Myocardial Infarction in Rats

(2011) Yoichi Sunagawa et al.   CIRCULATION JOURNAL

miR-146a–Mediated Extracellular Matrix Protein Production in Chronic Diabetes Complications

(2011) Biao Feng et al.   DIABETES

Histone deacetylase 1/2 mediates proliferation of renal interstitial fibroblasts and expression of cell cycle proteins

(2011) Maoyin Pang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor

(2010) Erin M. Bowers et al.   CHEMISTRY & BIOLOGY

STAT3-dependent effects of IL-22 in human keratinocytes are counterregulated by sirtuin 1 through a direct inhibition of STAT3 acetylation

(2010) Rosanna Sestito et al.   FASEB JOURNAL

Prevention of Angiotensin II–Mediated Renal Oxidative Stress, Inflammation, and Fibrosis by Angiotensin-Converting Enzyme 2

(2010) JiuChang Zhong et al.   HYPERTENSION

Role of inflammation in túbulo-interstitial damage associated to obstructive nephropathy

(2010) María T Grande et al.   Journal of Inflammation-London

Transcriptional coactivator p300 regulates glucose-induced gene expression in endothelial cells

(2009) Shali Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation

(2009) Chao Huang et al.   EMBO JOURNAL

Angiotensin II type 2 receptor mediated angiotensin II and high glucose induced decrease in renal prorenin/renin receptor expression

(2009) Ming He et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-κB

(2009) Jane Chiu et al.   NUTRITION

Angiotensin II activates JAK2/STAT3 pathway and induces interleukin-6 production in cultured rat brainstem astrocytes

(2009) Umadevi Kandalam et al.   REGULATORY PEPTIDES

Renal Damage Inhibited in Mice Lacking Angiotensinogen Gene Subjected to Unilateral Ureteral Obstruction

(2009) Yasumitsu Uchida et al.   UROLOGY

Ethanol inhibition of Angiotensin II-stimulated Tyr705 and Ser727 STAT3 phosphorylation in cultured rat hepatocytes: Relevance to activation of p42/44 mitogen-activated protein kinase

(2008) Yu.-I. Weng et al.   ALCOHOL

The STAT3 NH2-terminal Domain Stabilizes Enhanceosome Assembly by Interacting with the p300 Bromodomain

(2008) Tieying Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY