Auto-acetylation stabilizes p300 in cardiac myocytes during acute oxidative stress, promoting STAT3 accumulation and cell survival

Modulation of Anthracycline-Induced Cardiotoxicity by Aerobic Exercise in Breast Cancer

(2011) Jessica M. Scott et al.   CIRCULATION

Troponin I and C-Reactive Protein Are Commonly Detected in Patients with Breast Cancer Treated with Dose-Dense Chemotherapy Incorporating Trastuzumab and Lapatinib

(2011) P. G. Morris et al.   CLINICAL CANCER RESEARCH

Life and death of transcriptional co-activator p300

(2011) Jihong Chen et al.   Epigenetics

The Type III Histone Deacetylase Sirt1 Protein Suppresses p300-mediated Histone H3 Lysine 56 Acetylation at Bclaf1 Promoter to Inhibit T Cell Activation

(2011) Sinyi Kong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anthracycline-Associated Cardiotoxicity in Survivors of Childhood Cancer

(2011) Barry H. Trachtenberg et al.   PEDIATRIC CARDIOLOGY

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

(2010) Kerstin Boengler et al.   BASIC RESEARCH IN CARDIOLOGY

Priming of Signal Transducer and Activator of Transcription Proteins for Cytokine-Triggered Polyubiquitylation and Degradation by the A2A Adenosine Receptor

(2010) M. M. A. Safhi et al.   MOLECULAR PHARMACOLOGY

Cardiotoxicity of anticancer treatments: what the cardiologist needs to know

(2010) Michael S. Ewer et al.   Nature Reviews Cardiology

Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker

(2009) P N Munster et al.   BRITISH JOURNAL OF CANCER

A concise description of cardioprotective strategies in doxorubicin-induced cardiotoxicityThis article is one of a selection of papers published in a special issue celebrating the 125th anniversary of the Faculty of Medicine at the University of Manitoba.

(2009) Ana R. Lehenbauer Ludke et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Clinical Studies of Histone Deacetylase Inhibitors

(2009) H. M. Prince et al.   CLINICAL CANCER RESEARCH

Histone acetyl transferases as emerging drug targets

(2009) Frank J. Dekker et al.   DRUG DISCOVERY TODAY

HDAC2 regulates chromatin plasticity and enhances DNA vulnerability

(2009) D. C. Marchion et al.   MOLECULAR CANCER THERAPEUTICS

Histone modifying enzymes: Structures, mechanisms, and specificities

(2008) Ronen Marmorstein et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The EGFR-STAT3 Oncogenic Pathway Up-regulates the Eme1 Endonuclease to Reduce DNA Damage after Topoisomerase I Inhibition

(2008) A. Vigneron et al.   CANCER RESEARCH

Quantitative Control of Adaptive Cardiac Hypertrophy by Acetyltransferase p300

(2008) Jian Qin Wei et al.   CIRCULATION

Myocardial Regulation of p300 and p53 by Doxorubicin Involves Ubiquitin Pathways

(2008) Tatsuya Morimoto et al.   CIRCULATION JOURNAL

Histone deacetylase inhibitors: Anticancer compounds

(2008) Karen T. Smith et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Late Cardiac Effects of Adjuvant Chemotherapy in Breast Cancer Survivors Treated on Southwest Oncology Group Protocol S8897

(2008) Patricia A. Ganz et al.   JOURNAL OF CLINICAL ONCOLOGY

The SIRT2 Deacetylase Regulates Autoacetylation of p300

(2008) Joshua C. Black et al.   MOLECULAR CELL

Requirement of histone deacetylase1 (HDAC1) in signal transducer and activator of transcription 3 (STAT3) nucleocytoplasmic distribution

(2008) S. Ray et al.   NUCLEIC ACIDS RESEARCH

Cardioprotection by Ischemic Postconditioning Is Lost in Aged and STAT3-Deficient Mice

(2007) Kerstin Boengler et al.   CIRCULATION RESEARCH