Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer’s disease

Role of Oxidative Stress in the Progression of Alzheimer's Disease

(2017) Rukhsana Sultana et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer’s disease

(2012) A-Ryeong Gwon et al.   AGING CELL

Antioxidants for Alzheimer Disease

(2012) Douglas R. Galasko et al.   ARCHIVES OF NEUROLOGY

Modification of γ-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease

(2012) Francesc X. Guix et al.   EMBO Molecular Medicine

An over-oxidized form of superoxide dismutase found in sporadic amyotrophic lateral sclerosis with bulbar onset shares a toxic mechanism with mutant SOD1

(2012) S. Guareschi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease

(2011) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Amyloid-Dependent and Amyloid-Independent Stages of Alzheimer Disease

(2011) Bradley T. Hyman   ARCHIVES OF NEUROLOGY

Amyloid β peptide oligomers directly activate NMDA receptors

(2011) Laura Texidó et al.   CELL CALCIUM

Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation

(2011) Kengo Uemura et al.   Molecular Neurodegeneration

Potent amyloidogenicity and pathogenicity of Aβ43

(2011) Takashi Saito et al.   NATURE NEUROSCIENCE

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

(2010) Inna Kuperstein et al.   EMBO JOURNAL

Roles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease

(2010) D. Allan Butterfield et al.   FREE RADICAL RESEARCH

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

(2010) Daryl A Bosco et al.   NATURE NEUROSCIENCE

The secretases: enzymes with therapeutic potential in Alzheimer disease

(2010) Bart De Strooper et al.   Nature Reviews Neurology

Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update

(2009) Ian R. A. Mackenzie et al.   ACTA NEUROPATHOLOGICA

Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease

(2009) Clifford R. Jack et al.   BRAIN

The 28-amino acid form of an APLP1-derived Aβ-like peptide is a surrogate marker for Aβ42 production in the central nervous system

(2009) Kanta Yanagida et al.   EMBO Molecular Medicine

Beta-Amyloid Deposition and the Aging Brain

(2009) Karen M. Rodrigue et al.   NEUROPSYCHOLOGY REVIEW

Gender- and Age-Dependent γ-Secretase Activity in Mouse Brain and Its Implication in Sporadic Alzheimer Disease

(2009) Lisa Placanica et al.   PLoS One

Allosteric Modulation of PS1/γ-Secretase Conformation Correlates with Amyloid β42/40 Ratio

(2009) Kengo Uemura et al.   PLoS One

Oligomeric amyloid   associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

(2009) R. M. Koffie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Secretase Heterogeneity in the Aph1 Subunit: Relevance for Alzheimer's Disease

(2009) L. Serneels et al.   SCIENCE

Frontotemporal dementia and related disorders: Deciphering the enigma

(2008) Keith A. Josephs   ANNALS OF NEUROLOGY

Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy

(2008) Phillip B. Jones et al.   JOURNAL OF BIOMEDICAL OPTICS

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON