Properdin Regulation of Complement Activation Affects Colitis in Interleukin 10 Gene–Deficient Mice

The Complement System in Inflammatory Bowel Disease

(2014) Umang Jain et al.   INFLAMMATORY BOWEL DISEASES

Properdin Deficiency in Murine Models of Nonseptic Shock

(2014) N. D. Ivanovska et al.   JOURNAL OF IMMUNOLOGY

Inhibition of the Membrane Attack Complex of the Complement System Reduces Secondary Neuroaxonal Loss and Promotes Neurologic Recovery after Traumatic Brain Injury in Mice

(2014) K. Fluiter et al.   JOURNAL OF IMMUNOLOGY

Inflammasome activation has an important role in the development of spontaneous colitis

(2014) J Zhang et al.   Mucosal Immunology

Combined NADPH Oxidase 1 and Interleukin 10 Deficiency Induces Chronic Endoplasmic Reticulum Stress and Causes Ulcerative Colitis-Like Disease in Mice

(2014) Xavier Tréton et al.   PLoS One

Blocking Properdin, the Alternative Pathway, and Anaphylatoxin Receptors Ameliorates Renal Ischemia-Reperfusion Injury in Decay-Accelerating Factor and CD59 Double-Knockout Mice

(2013) T. Miwa et al.   JOURNAL OF IMMUNOLOGY

IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis

(2013) C. L. Zindl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10

(2012) U Jain et al.   BRITISH JOURNAL OF PHARMACOLOGY

p40phox Expression Regulates Neutrophil Recruitment and Function during the Resolution Phase of Intestinal Inflammation

(2012) K. L. Conway et al.   JOURNAL OF IMMUNOLOGY

Complement-Dependent Injury and Protection in a Murine Model of Acute Dextran Sulfate Sodium-Induced Colitis

(2012) J. Schepp-Berglind et al.   JOURNAL OF IMMUNOLOGY

Loss of Properdin Exacerbates C3 Glomerulopathy Resulting from Factor H Deficiency

(2012) M. M. Ruseva et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The role of neutrophils during intestinal inflammation

(2012) B M Fournier et al.   Mucosal Immunology

Abrogated RANKL expression in properdin-deficient mice is associated with better outcome from collagen-antibody-induced arthritis

(2012) Petya Dimitrova et al.   ARTHRITIS RESEARCH & THERAPY

MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice

(2012) Namiko Hoshi et al.   Nature Communications

Colitis and Intestinal Inflammation in IL10−/− Mice Results From IL-13Rα2–Mediated Attenuation of IL-13 Activity

(2010) Mark S. Wilson et al.   GASTROENTEROLOGY

Commensal gut flora reduces susceptibility to experimentally induced colitis via T-cell-derived interleukin-101

(2010) Marina C. Pils et al.   INFLAMMATORY BOWEL DISEASES

Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury

(2010) Yuko Kimura et al.   JOURNAL OF CLINICAL INVESTIGATION

Blockade of complement activation product C5a activity using specific antibody attenuates intestinal damage in trinitrobenzene sulfonic acid induced model of colitis

(2010) Guojiang Chen et al.   LABORATORY INVESTIGATION

The role of properdin in murine zymosan-induced arthritis

(2010) Petya Dimitrova et al.   MOLECULAR IMMUNOLOGY

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Role of Mast Cells in Inflammatory Bowel Disease and Inflammation-Associated Colorectal Neoplasia in IL-10-Deficient Mice

(2010) Maciej Chichlowski et al.   PLoS One

Complement-Dependent Neutrophil Recruitment Is Critical for the Development of Elastase-Induced Abdominal Aortic Aneurysm

(2009) Monica B. Pagano et al.   CIRCULATION

Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate-induced models of inflammatory bowel disease

(2009) Kay Johswich et al.   INFLAMMATORY BOWEL DISEASES

CXCR2-Dependent Mucosal Neutrophil Influx Protects against Colitis-Associated Diarrhea Caused by an Attaching/Effacing Lesion-Forming Bacterial Pathogen

(2009) M. E. Spehlmann et al.   JOURNAL OF IMMUNOLOGY

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

The alternative complement pathway revisited

(2008) Morten Harboe et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

(2008) Andre Franke et al.   NATURE GENETICS