Microbial DNA Recognition by cGAS-STING and Other Sensors in Dendritic Cells in Inflammatory Bowel Diseases
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Microbial DNA Recognition by cGAS-STING and Other Sensors in Dendritic Cells in Inflammatory Bowel Diseases
Authors
Keywords
-
Journal
INFLAMMATORY BOWEL DISEASES
Volume 21, Issue 4, Pages 901-911
Publisher
Oxford University Press (OUP)
Online
2015-01-12
DOI
10.1097/mib.0000000000000299
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Receptor-Interacting Protein Homotypic Interaction Motif-Dependent Control of NF- B Activation via the DNA-Dependent Activator of IFN Regulatory Factors
- (2014) W. J. Kaiser et al. JOURNAL OF IMMUNOLOGY
- Cytosolic-DNA-Mediated, STING-Dependent Proinflammatory Gene Induction Necessitates Canonical NF- B Activation through TBK1
- (2014) T. Abe et al. JOURNAL OF VIROLOGY
- The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling
- (2014) Xin Cai et al. MOLECULAR CELL
- The Mucosal Adjuvant Cyclic di-AMP Exerts Immune Stimulatory Effects on Dendritic Cells and Macrophages
- (2014) Ivana Škrnjug et al. PLoS One
- HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation
- (2014) Maria Kalamvoki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling
- (2013) Hiroyasu Konno et al. CELL
- Human Cytomegalovirus Tegument Protein pUL83 Inhibits IFI16-Mediated DNA Sensing for Immune Evasion
- (2013) Tuo Li et al. Cell Host & Microbe
- Species-specific detection of the antiviral small-molecule compound CMA by STING
- (2013) Taner Cavlar et al. EMBO JOURNAL
- The Capsids of HIV-1 and HIV-2 Determine Immune Detection of the Viral cDNA by the Innate Sensor cGAS in Dendritic Cells
- (2013) Xavier Lahaye et al. IMMUNITY
- IRF4 Transcription-Factor-Dependent CD103+CD11b+ Dendritic Cells Drive Mucosal T Helper 17 Cell Differentiation
- (2013) Emma K. Persson et al. IMMUNITY
- IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses
- (2013) Andreas Schlitzer et al. IMMUNITY
- Luminal Bacteria Recruit CD103+ Dendritic Cells into the Intestinal Epithelium to Sample Bacterial Antigens for Presentation
- (2013) Julia Farache et al. IMMUNITY
- Identification of a negative feedback loop between cyclic di-GMP-induced levels of IFI16 and p202 cytosolic DNA sensors and STING
- (2013) Ravichandran Panchanathan et al. Innate Immunity
- Cutting Edge: DNA Sensing via the STING Adaptor in Myeloid Dendritic Cells Induces Potent Tolerogenic Responses
- (2013) L. Huang et al. JOURNAL OF IMMUNOLOGY
- Self Double-Stranded (ds)DNA Induces IL-1 Production from Human Monocytes by Activating NLRP3 Inflammasome in the Presence of Anti-dsDNA Antibodies
- (2013) M. S. Shin et al. JOURNAL OF IMMUNOLOGY
- Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid
- (2013) J. Conlon et al. JOURNAL OF IMMUNOLOGY
- MPYS/STING-Mediated TNF- , Not Type I IFN, Is Essential for the Mucosal Adjuvant Activity of (3'-5')-Cyclic-Di-Guanosine-Monophosphate In Vivo
- (2013) S. M. Blaauboer et al. JOURNAL OF IMMUNOLOGY
- Proteasomal Degradation of Herpes Simplex Virus Capsids in Macrophages Releases DNA to the Cytosol for Recognition by DNA Sensors
- (2013) K. A. Horan et al. JOURNAL OF IMMUNOLOGY
- Constitutive Interferon-Inducible Protein 16-Inflammasome Activation during Epstein-Barr Virus Latency I, II, and III in B and Epithelial Cells
- (2013) M. A. Ansari et al. JOURNAL OF VIROLOGY
- Kaposi's Sarcoma-Associated Herpesvirus Latency in Endothelial and B Cells Activates Gamma Interferon-Inducible Protein 16-Mediated Inflammasomes
- (2013) V. V. Singh et al. JOURNAL OF VIROLOGY
- STING Recognition of Cytoplasmic DNA Instigates Cellular Defense
- (2013) Takayuki Abe et al. MOLECULAR CELL
- Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice
- (2013) Payal B Watchmaker et al. NATURE IMMUNOLOGY
- PNAS Plus: From the Cover: IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication
- (2013) M. R. Jakobsen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking
- (2013) T. Kondo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects
- (2013) X.-D. Li et al. SCIENCE
- Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses
- (2013) D. Gao et al. SCIENCE
- STING-dependent cytosolic DNA sensing pathways
- (2013) Glen N. Barber TRENDS IN IMMUNOLOGY
- Innate immune detection of microbial nucleic acids
- (2013) Claudia Gürtler et al. TRENDS IN MICROBIOLOGY
- The mammalian PYHIN gene family: Phylogeny, evolution and expression
- (2012) Jasmyn A Cridland et al. BMC EVOLUTIONARY BIOLOGY
- Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
- (2012) Kenichi Shimada et al. IMMUNITY
- IFN- Expression Is Directly Activated in Human Neutrophils Transfected with Plasmid DNA and Is Further Increased via TLR-4-Mediated Signaling
- (2012) N. Tamassia et al. JOURNAL OF IMMUNOLOGY
- Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine
- (2012) Jeremiah R. McDole et al. NATURE
- The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response
- (2012) Kislay Parvatiyar et al. NATURE IMMUNOLOGY
- The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA
- (2012) Zhiqiang Zhang et al. NATURE IMMUNOLOGY
- Innate sensing of bacterial cyclic dinucleotides: more than just STING
- (2012) Andrew G Bowie NATURE IMMUNOLOGY
- Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein
- (2012) M. H. Orzalli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection
- (2012) Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
- (2012) J. Wu et al. SCIENCE
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway
- (2012) Y. Tanaka et al. Science Signaling
- IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
- (2011) Nagaraj Kerur et al. Cell Host & Microbe
- The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes
- (2011) Yun-Gi Kim et al. IMMUNITY
- Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina Propria
- (2011) Usriansyah Hadis et al. IMMUNITY
- Functional Specializations of Intestinal Dendritic Cell and Macrophage Subsets That Control Th17 and Regulatory T Cell Responses Are Dependent on the T Cell/APC Ratio, Source of Mouse Strain, and Regional Localization
- (2011) T. L. Denning et al. JOURNAL OF IMMUNOLOGY
- Cytosolic DNA-Activated Human Dendritic Cells Are Potent Activators of the Adaptive Immune Response
- (2011) K. Kis-Toth et al. JOURNAL OF IMMUNOLOGY
- DHX9 Pairs with IPS-1 To Sense Double-Stranded RNA in Myeloid Dendritic Cells
- (2011) Z. Zhang et al. JOURNAL OF IMMUNOLOGY
- A New Subset of CD103+CD8 + Dendritic Cells in the Small Intestine Expresses TLR3, TLR7, and TLR9 and Induces Th1 Response and CTL Activity
- (2011) K. Fujimoto et al. JOURNAL OF IMMUNOLOGY
- MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP
- (2011) L. Jin et al. JOURNAL OF IMMUNOLOGY
- DDX60, a DEXD/H Box Helicase, Is a Novel Antiviral Factor Promoting RIG-I-Like Receptor-Mediated Signaling
- (2011) M. Miyashita et al. MOLECULAR AND CELLULAR BIOLOGY
- Differential Roles for the Interferon-Inducible IFI16 and AIM2 Innate Immune Sensors for Cytosolic DNA in Cellular Senescence of Human Fibroblasts
- (2011) X. Duan et al. MOLECULAR CANCER RESEARCH
- STING is a direct innate immune sensor of cyclic di-GMP
- (2011) Dara L. Burdette et al. NATURE
- The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
- (2011) Zhiqiang Zhang et al. NATURE IMMUNOLOGY
- TheN-Ethyl-N-Nitrosourea-InducedGoldenticketMouse Mutant Reveals an Essential Function ofStingin theIn VivoInterferon Response toListeria monocytogenesand Cyclic Dinucleotides
- (2010) John-Demian Sauer et al. INFECTION AND IMMUNITY
- NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
- (2010) Simon A. Hirota et al. INFLAMMATORY BOWEL DISEASES
- The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a β-catenin-dependent pathway
- (2010) Pengyuan Yang et al. NATURE IMMUNOLOGY
- IFI16 is an innate immune sensor for intracellular DNA
- (2010) Leonie Unterholzner et al. NATURE IMMUNOLOGY
- Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells
- (2010) T. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-κB
- (2009) Manuele Rebsamen et al. EMBO REPORTS
- Intestinal Lamina Propria Dendritic Cell Subsets Have Different Origin and Functions
- (2009) Chen Varol et al. IMMUNITY
- Origin of the Lamina Propria Dendritic Cell Network
- (2009) Milena Bogunovic et al. IMMUNITY
- Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions
- (2009) Olga Schulz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
- (2009) Teresa Fernandes-Alnemri et al. NATURE
- AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
- (2009) Veit Hornung et al. NATURE
- HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses
- (2009) Hideyuki Yanai et al. NATURE
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
- Activation of innate immune antiviral responses by Nod2
- (2009) Ahmed Sabbah et al. NATURE IMMUNOLOGY
- An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
- (2009) Tilmann Bürckstümmer et al. NATURE IMMUNOLOGY
- Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
- (2009) T. Saitoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA
- (2009) T. L. Roberts et al. SCIENCE
- TLR9 as a key receptor for the recognition of DNA☆
- (2008) Y KUMAGAI et al. ADVANCED DRUG DELIVERY REVIEWS
- The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
- (2008) Bo Zhong et al. IMMUNITY
- MPYS, a Novel Membrane Tetraspanner, Is Associated with Major Histocompatibility Complex Class II and Mediates Transduction of Apoptotic Signals
- (2008) L. Jin et al. MOLECULAR AND CELLULAR BIOLOGY
- TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
- (2008) Ken J. Ishii et al. NATURE
- The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
- (2008) Daniel A. Muruve et al. NATURE
- ATP drives lamina propria TH17 cell differentiation
- (2008) Koji Atarashi et al. NATURE
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
- Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5
- (2008) Satoshi Uematsu et al. NATURE IMMUNOLOGY
- STRING 8--a global view on proteins and their functional interactions in 630 organisms
- (2008) L. J. Jensen et al. NUCLEIC ACIDS RESEARCH
- Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules
- (2008) Z. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now