Dominant negative FADD dissipates the proapoptotic signalosome of the unfolded protein response in diabetic embryopathy

Oxidative stress is responsible for maternal diabetes-impaired transforming growth factor beta signaling in the developing mouse heart

(2015) Fang Wang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Decoding the oxidative stress hypothesis in diabetic embryopathy through proapoptotic kinase signaling

(2015) Peixin Yang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Advances in revealing the molecular targets downstream of oxidative stress–induced proapoptotic kinase signaling in diabetic embryopathy

(2015) Fang Wang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Cellular Stress, Excessive Apoptosis, and the Effect of Metformin in a Mouse Model of Type 2 Diabetic Embryopathy

(2015) Yanqing Wu et al.   DIABETES

Ask1Gene Deletion Blocks Maternal Diabetes–Induced Endoplasmic Reticulum Stress in the Developing Embryo by Disrupting the Unfolded Protein Response Signalosome

(2014) Fang Wang et al.   DIABETES

The miR-322-TRAF3 Circuit Mediates the Pro-apoptotic Effect of High Glucose on Neural Stem Cells

(2014) Hui Gu et al.   TOXICOLOGICAL SCIENCES

Superoxide dismutase 1 overexpression in mice abolishes maternal diabetes–induced endoplasmic reticulum stress in diabetic embryopathy

(2013) Fang Wang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Trehalose prevents neural tube defects by correcting maternal diabetes-suppressed autophagy and neurogenesis

(2013) Cheng Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Maternal Hyperglycemia Activates an ASK1-FoxO3a-Caspase 8 Pathway That Leads to Embryonic Neural Tube Defects

(2013) P. Yang et al.   Science Signaling

The use of animal models in diabetes research

(2012) Aileen JF King   BRITISH JOURNAL OF PHARMACOLOGY

Oxidative Stress-Induced JNK1/2 Activation Triggers Proapoptotic Signaling and Apoptosis That Leads to Diabetic Embryopathy

(2012) X. Li et al.   DIABETES

c-Jun NH2-Terminal Kinase 1/2 and Endoplasmic Reticulum Stress as Interdependent and Reciprocal Causation in Diabetic Embryopathy

(2012) X. Li et al.   DIABETES

Failing to prevent birth defects caused by maternal diabetes mellitus

(2011) Godfrey P. Oakley   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Lack of periconceptional vitamins or supplements that contain folic acid and diabetes mellitus–associated birth defects

(2011) Adolfo Correa et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Neural tube defect genes and maternal diabetes during pregnancy

(2010) J. Michael Salbaum et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Signaling cell death from the endoplasmic reticulum stress response

(2010) Gordon C Shore et al.   CURRENT OPINION IN CELL BIOLOGY

Caspase-8: a key role in the pathogenesis of diabetic embryopathy

(2009) Zhiyong Zhao et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Maternal diabetes alters transcriptional programs in the developing embryo

(2009) Gabriela Pavlinkova et al.   BMC GENOMICS

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

Activation of oxidative stress signaling that is implicated in apoptosis with a mouse model of diabetic embryopathy

(2008) Peixin Yang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Diabetes mellitus and birth defects

(2008) Adolfo Correa et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Decreased Cardiac Glutathione Peroxidase Levels and Enhanced Mandibular Apoptosis in Malformed Embryos of Diabetic Rats

(2008) P. Wentzel et al.   DIABETES

Trends in the Prevalence of Preexisting Diabetes and Gestational Diabetes Mellitus Among a Racially/Ethnically Diverse Population of Pregnant Women, 1999-2005

(2008) J. M. Lawrence et al.   DIABETES CARE

Messenger RNA targeting to endoplasmic reticulum stress signalling sites

(2008) Tomás Aragón et al.   NATURE