Ask1Gene Deletion Blocks Maternal Diabetes–Induced Endoplasmic Reticulum Stress in the Developing Embryo by Disrupting the Unfolded Protein Response Signalosome

Superoxide dismutase 1 overexpression in mice abolishes maternal diabetes–induced endoplasmic reticulum stress in diabetic embryopathy

(2013) Fang Wang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Maternal Hyperglycemia Activates an ASK1-FoxO3a-Caspase 8 Pathway That Leads to Embryonic Neural Tube Defects

(2013) P. Yang et al.   Science Signaling

Nonmuscle Myosin IIB Links Cytoskeleton to IRE1α Signaling during ER Stress

(2012) Yin He et al.   DEVELOPMENTAL CELL

IRE1, a Double-Edged Sword in Pre-miRNA Slicing and Cell Death

(2012) Justin Hassler et al.   DEVELOPMENTAL CELL

Oxidative Stress-Induced JNK1/2 Activation Triggers Proapoptotic Signaling and Apoptosis That Leads to Diabetic Embryopathy

(2012) X. Li et al.   DIABETES

c-Jun NH2-Terminal Kinase 1/2 and Endoplasmic Reticulum Stress as Interdependent and Reciprocal Causation in Diabetic Embryopathy

(2012) X. Li et al.   DIABETES

IRE1  Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2

(2012) J.-P. Upton et al.   SCIENCE

TXNIP (VDUP-1, TBP-2): A major redox regulator commonly suppressed in cancer by epigenetic mechanisms

(2011) Jianbiao Zhou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Epigallocatechin-3-gallate ameliorates hyperglycemia-induced embryonic vasculopathy and malformation by inhibition of Foxo3a activation

(2010) Peixin Yang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Hyperglycemia induces inducible nitric oxide synthase gene expression and consequent nitrosative stress via c-Jun N-terminal kinase activation

(2010) Peixin Yang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Neural tube defect genes and maternal diabetes during pregnancy

(2010) J. Michael Salbaum et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Signaling cell death from the endoplasmic reticulum stress response

(2010) Gordon C Shore et al.   CURRENT OPINION IN CELL BIOLOGY

Maternal diabetes alters transcriptional programs in the developing embryo

(2009) Gabriela Pavlinkova et al.   BMC GENOMICS

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid-Induced ER Stress-Mediated  -Cell Death

(2009) J. Chen et al.   DIABETES

ATM blocks tunicamycin-induced endoplasmic reticulum stress

(2009) Long He et al.   FEBS LETTERS

Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability

(2009) T. Iwawaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diabetes mellitus and birth defects

(2008) Adolfo Correa et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Decreased Cardiac Glutathione Peroxidase Levels and Enhanced Mandibular Apoptosis in Malformed Embryos of Diabetic Rats

(2008) P. Wentzel et al.   DIABETES

The unfolded protein response signals through high-order assembly of Ire1

(2008) Alexei V. Korennykh et al.   NATURE

Messenger RNA targeting to endoplasmic reticulum stress signalling sites

(2008) Tomás Aragón et al.   NATURE