Expression of S6K1 in human visceral adipose tissue is upregulated in obesity and related to insulin resistance and inflammation

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

(2014) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A growing role for mTOR in promoting anabolic metabolism

(2013) Jessica J. Howell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Phosphorylation and degradation of S6K1 (p70S6K1) in response to persistent JNK1 Activation

(2013) Jin Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Origins and Drivers of Insulin Resistance

(2013) Andrew M.F. Johnson et al.   CELL

Obesity: The Gateway to Ill Health - an EASO Position Statement on a Rising Public Health, Clinical and Scientific Challenge in Europe

(2013) Gema Frühbeck et al.   Obesity Facts

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Obesity and Cardiovascular Disease

(2012) Caroline M. Apovian et al.   CIRCULATION

Phosphorylated S6K1 (Thr389) is a molecular adipose tissue marker of altered glucose tolerance

(2012) José María Moreno-Navarrete et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Combined Deletion of S6K1 and Akt2 Deteriorates Glycemic Control in a High-Fat Diet

(2012) C. Treins et al.   MOLECULAR AND CELLULAR BIOLOGY

mTOR signalling: the molecular interface connecting metabolic stress, aging and cardiovascular diseases

(2012) Z. Yang et al.   Obesity Reviews

JNK Expression by Macrophages Promotes Obesity-Induced Insulin Resistance and Inflammation

(2012) M. S. Han et al.   SCIENCE

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt

(2011) Ruomin Di et al.   BIOCHEMICAL JOURNAL

Clinical Usefulness of a New Equation for Estimating Body Fat

(2011) J. Gomez-Ambrosi et al.   DIABETES CARE

Body mass index classification misses subjects with increased cardiometabolic risk factors related to elevated adiposity

(2011) J Gómez-Ambrosi et al.   INTERNATIONAL JOURNAL OF OBESITY

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased levels of chemerin and its receptor, chemokine-like receptor-1, in obesity are related to inflammation: tumor necrosis factor-α stimulates mRNA levels of chemerin in visceral adipocytes from obese patients

(2011) Victoria Catalán et al.   Surgery for Obesity and Related Diseases

cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistance

(2010) Guadalupe Sabio et al.   TRENDS IN BIOCHEMICAL SCIENCES

Improved insulin sensitivity by calorie restriction is associated with reduction of ERK and p70S6K activities in the liver of obese Zucker rats

(2009) Yanbin Zheng et al.   JOURNAL OF ENDOCRINOLOGY

Inflammation is associated with a decrease of lipogenic factors in omental fat in women

(2008) Odile Poulain-Godefroy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Rescuing 3T3-L1 Adipocytes from Insulin Resistance Induced by Stimulation of Akt-Mammalian Target of Rapamycin/p70 S6 Kinase (S6K1) Pathway and Serine Phosphorylation of Insulin Receptor Substrate-1: Effect of Reduced Expression of p85α Subunit of Phosphatidylinositol 3-Kinase and S6K1 Kinase

(2008) Rebecca Adochio et al.   ENDOCRINOLOGY

S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF-α Signaling through IKK2

(2008) Jin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY