Rorα deficiency and decreased adiposity are associated with induction of thermogenic gene expression in subcutaneous white adipose and brown adipose tissue

Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

(2014) Paul Cohen et al.   CELL

Beyond the Sympathetic Tone: The New Brown Fat Activators

(2013) Francesc Villarroya et al.   Cell Metabolism

A Classical Brown Adipose Tissue mRNA Signature Partly Overlaps with Brite in the Supraclavicular Region of Adult Humans

(2013) Naja Zenius Jespersen et al.   Cell Metabolism

Adipose Subtype-Selective Recruitment of TLE3 or Prdm16 by PPARγ Specifies Lipid Storage versus Thermogenic Gene Programs

(2013) Claudio J. Villanueva et al.   Cell Metabolism

When BAT is lacking, WAT steps up

(2013) Andrew Whittle et al.   CELL RESEARCH

EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex

(2013) Haruya Ohno et al.   NATURE

Evidence for two types of brown adipose tissue in humans

(2013) Martin E Lidell et al.   NATURE MEDICINE

Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat

(2013) Aaron M Cypess et al.   NATURE MEDICINE

Cidea promotes hepatic steatosis by sensing dietary fatty acids

(2012) Linkang Zhou et al.   HEPATOLOGY

Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition

(2012) Hiroyuki Mori et al.   JOURNAL OF CLINICAL INVESTIGATION

SkiOverexpression in Skeletal Muscle Modulates Genetic Programs That Control Susceptibility to Diet-Induced Obesity and Insulin Signaling

(2012) Marianne Diaz et al.   Obesity

Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance

(2012) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of Thyroid Hormone Activation in Type 2 Deiodinase Knockout Mice Causes Obesity With Glucose Intolerance and Liver Steatosis Only at Thermoneutrality

(2011) M. Castillo et al.   DIABETES

Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle

(2011) P. Lau et al.   DIABETOLOGIA

Nr4a1 siRNA Expression Attenuates α-MSH Regulated Gene Expression in 3T3-L1 Adipocytes

(2011) S.-C. Mary Wang et al.   MOLECULAR ENDOCRINOLOGY

Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRα in human UCP1 expression

(2010) Daniel L Morganstein et al.   CELL RESEARCH

Identification and validation of the pathways and functions regulated by the orphan nuclear receptor, ROR alpha1, in skeletal muscle

(2010) S. Raichur et al.   NUCLEIC ACIDS RESEARCH

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

Inhibition of adipocyte differentiation by RORα

(2009) Hélène Duez et al.   FEBS LETTERS

The Orphan Nuclear Receptor RORα Restrains Adipocyte Differentiation through a Reduction of C/EBPβ Activity and Perilipin Gene Expression

(2009) Nobumichi Ohoka et al.   MOLECULAR ENDOCRINOLOGY

Initiation of myoblast to brown fat switch by a PRDM16–C/EBP-β transcriptional complex

(2009) Shingo Kajimura et al.   NATURE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Orphan Nuclear Receptor, RORα, Regulates Gene Expression That Controls Lipid Metabolism

(2008) Patrick Lau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Functional Interaction between RIP140 and PGC-1  Regulates the Expression of the Lipid Droplet Protein CIDEA

(2008) M. Hallberg et al.   MOLECULAR AND CELLULAR BIOLOGY

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE