Role of chaperone-mediated autophagy in degrading Huntington's disease-associated huntingtin protein

Indirect inhibition of 26S proteasome activity in a cellular model of Huntington’s disease

(2012) Mark S. Hipp et al.   JOURNAL OF CELL BIOLOGY

The Role of Chaperone-Mediated Autophagy in Huntingtin Degradation

(2012) Lin Qi et al.   PLoS One

Constitutive Upregulation of Chaperone-Mediated Autophagy in Huntington's Disease

(2011) H. Koga et al.   JOURNAL OF NEUROSCIENCE

A photoconvertible fluorescent reporter to track chaperone-mediated autophagy

(2011) Hiroshi Koga et al.   Nature Communications

Does Huntingtin play a role in selective macroautophagy?

(2010) Joan S. Steffan   CELL CYCLE

Huntington's disease: progress toward effective disease-modifying treatments and a cure

(2010) C. D. Johnson et al.   HUMAN MOLECULAR GENETICS

Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy

(2010) Fiona M. Menzies et al.   HUMAN MOLECULAR GENETICS

Tracking Mutant Huntingtin Aggregation Kinetics in Cells Reveals Three Major Populations That Include an Invariant Oligomer Pool

(2010) Maya A. Olshina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein

(2010) Peter O Bauer et al.   NATURE BIOTECHNOLOGY

Chaperone-mediated autophagy dysfunction in the pathogenesis of neurodegeneration

(2010) Hiroshi Koga et al.   NEUROBIOLOGY OF DISEASE

Chaperone-mediated autophagy: Molecular mechanisms and physiological relevance

(2010) Samantha J. Orenstein et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation

(2009) Hyunkyung Jeong et al.   CELL

Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways

(2009) Heng Liu et al.   FASEB JOURNAL

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

(2009) Yipeng Wang et al.   HUMAN MOLECULAR GENETICS

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

(2009) Leslie Michels Thompson et al.   JOURNAL OF CELL BIOLOGY

Mammalian macroautophagy at a glance

(2009) B. Ravikumar et al.   JOURNAL OF CELL SCIENCE

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

(2009) Viktor I. Korolchuk et al.   MOLECULAR CELL

IKKα and IKKβ Regulation of DNA Damage-Induced Cleavage of Huntingtin

(2009) Ali Khoshnan et al.   PLoS One

Chaperone-mediated autophagy: selectivity pays off

(2009) Ana Maria Cuervo   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Proteasome activation as a novel antiaging strategy

(2008) Niki Chondrogianni et al.   IUBMB LIFE

Impaired ubiquitin–proteasome system activity in the synapses of Huntington's disease mice

(2008) Jianjun Wang et al.   JOURNAL OF CELL BIOLOGY

Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease

(2008) B. Ravikumar et al.   JOURNAL OF CELL SCIENCE

Genetic Evidence Linking Age-Dependent Attenuation of the 26S Proteasome with the Aging Process

(2008) A. Tonoki et al.   MOLECULAR AND CELLULAR BIOLOGY

The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane

(2008) U. Bandyopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY

Constitutive Activation of Chaperone-mediated Autophagy in Cells with Impaired Macroautophagy

(2008) Susmita Kaushik et al.   MOLECULAR BIOLOGY OF THE CELL

Dual contrasting roles of cysteine cathepsins in cancer progression: Apoptosis versus tumour invasion

(2007) Olga Vasiljeva et al.   BIOCHIMIE