Advancing drug delivery systems for the treatment of multiple sclerosis

Role of obinutuzumab in the treatment of chronic lymphocytic leukemia

(2015) G. W. Jean et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

New FDA-Approved Disease-Modifying Therapies for Multiple Sclerosis

(2015) Clayton English et al.   CLINICAL THERAPEUTICS

DCIR2+cDC2 DCs and Zbtb32 Restore CD4+T-Cell Tolerance and Inhibit Diabetes

(2015) Jeffrey D. Price et al.   DIABETES

Peripherally Induced Tolerance Depends on Peripheral Regulatory T Cells That Require Hopx To Inhibit Intrinsic IL-2 Expression

(2015) Andrew Jones et al.   JOURNAL OF IMMUNOLOGY

Multiple Sclerosis

(2015) Daniel Kane Files et al.   PRIMARY CARE

Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

(2015) Yonghao Cao et al.   Science Translational Medicine

Dimethyl fumarate in the treatment of relapsing–remitting multiple sclerosis: an overview

(2015) Roberto Bomprezzi   Therapeutic Advances in Neurological Disorders

A Biodegradable Nanoparticle Platform for the Induction of Antigen-Specific Immune Tolerance for Treatment of Autoimmune Disease

(2014) Zoe Hunter et al.   ACS Nano

Multiple Sclerosis: Current Knowledge and Future Outlook

(2014) Christian P. Kamm et al.   EUROPEAN NEUROLOGY

CD8+CD205+ Splenic Dendritic Cells Are Specialized to Induce Foxp3+ Regulatory T Cells

(2014) S. Yamazaki et al.   JOURNAL OF IMMUNOLOGY

Multiple Sclerosis: Current and Emerging Disease-Modifying Therapies and Treatment Strategies

(2014) Dean M. Wingerchuk et al.   MAYO CLINIC PROCEEDINGS

Targeting Innate Receptors with MIS416 Reshapes Th Responses and Suppresses CNS Disease in a Mouse Model of Multiple Sclerosis

(2014) Madeleine White et al.   PLoS One

Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance

(2014) Roberto A. Maldonado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Nanotechnology: From Sensing and DNA Machines to Drug-Delivery Systems

(2013) Chun-Hua Lu et al.   ACS Nano

Dimethyl Fumarate for Treatment of Multiple Sclerosis: Mechanism of Action, Effectiveness, and Side Effects

(2013) Ralf A. Linker et al.   Current Neurology and Neuroscience Reports

Recognition of BisectingN-Acetylglucosamine

(2013) Masamichi Nagae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paclitaxel-loaded polymeric microparticles: Quantitative relationships between in vitro drug release rate and in vivo pharmacodynamics

(2013) Max Tsai et al.   JOURNAL OF CONTROLLED RELEASE

Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties

(2013) Christian Klein et al.   mAbs

Microparticle surface modifications targeting dendritic cells for non-activating applications

(2012) Jamal S. Lewis et al.   BIOMATERIALS

Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation

(2012) Pieter J. Gaillard et al.   JOURNAL OF CONTROLLED RELEASE

Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis

(2012) Daniel R Getts et al.   NATURE BIOTECHNOLOGY

Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis

(2011) Jeffrey A. Cohen et al.   ANNALS OF NEUROLOGY

Induction of anti-tumor cytotoxic T cell responses through PLGA-nanoparticle mediated antigen delivery

(2011) Zhiping Zhang et al.   BIOMATERIALS

Immune mechanisms of new therapeutic strategies in MS — Teriflunomide

(2011) Malte C. Claussen et al.   CLINICAL IMMUNOLOGY

Glatiramer Acetate in the Treatment of Multiple Sclerosis

(2011) Patrice H. Lalive et al.   CNS DRUGS

Dendritic cell-associated lectin 2 (DCAL2) defines a distinct CD8α− dendritic cell subset

(2011) Shinji Kasahara et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Preparation of pH-Responsive Mesoporous Silica Nanoparticles and Their Application in Controlled Drug Delivery

(2011) Li Yuan et al.   Journal of Physical Chemistry C

Autoimmune disease after alemtuzumab treatment for multiple sclerosis in a multicenter cohort

(2011) M. Cossburn et al.   NEUROLOGY

Long-term treatment of multiple sclerosis with glatiramer acetate: Natural history of the subtypes of anti-glatiramer acetate antibodies and their correlation with clinical efficacy

(2010) Dimitros Karussis et al.   JOURNAL OF NEUROIMMUNOLOGY

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

(2010) Kamran Ghoreschi et al.   NATURE

Therapeutic cell engineering with surface-conjugated synthetic nanoparticles

(2010) Matthias T Stephan et al.   NATURE MEDICINE

Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells

(2010) J. N. H. Stern et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treatment of Cartilage Defects in the Knee Using Alginate Beads Containing Human Mature Allogenic Chondrocytes

(2009) Karl Fredrik Almqvist et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Redox- and pH-Controlled Mechanized Nanoparticles

(2009) Niveen M. Khashab et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

HLA-DQB1*0602 Determines Disease Susceptibility in a New "Humanized" Multiple Sclerosis Model in HLA-DR15 (DRB1*1501;DQB1*0602) Transgenic Mice

(2009) N. Kaushansky et al.   JOURNAL OF IMMUNOLOGY

Plasmacytoid Dendritic Cells in Multiple Sclerosis

(2009) Roberto Lande et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mesoporous Silica Nanoparticle-Based Double Drug Delivery System for Glucose-Responsive Controlled Release of Insulin and Cyclic AMP

(2009) Yannan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Materials engineering for immunomodulation

(2009) Jeffrey A. Hubbell et al.   NATURE

Interferon-  mechanisms of action in multiple sclerosis

(2009) S. Dhib-Jalbut et al.   NEUROLOGY

Acute in vivo exposure to interferon-  enables resident brain dendritic cells to become effective antigen presenting cells

(2009) A. Gottfried-Blackmore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

(2009) Fiona A. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of phagosomal pH on the size-dependent efficiency of cross-presentation by dendritic cells

(2008) Kenny K. Tran et al.   BIOMATERIALS

Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles

(2008) Christian Wischke et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

(2008) Mirjam Kool et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Temporal trends in the incidence of multiple sclerosis: A systematic review

(2008) A. Alonso et al.   NEUROLOGY

B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis

(2008) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of Particle Size in Phagocytosis of Polymeric Microspheres

(2008) Julie A. Champion et al.   PHARMACEUTICAL RESEARCH