Article
Chemistry, Physical
Xiu Qin, Chunling Yuan, Rui Shi, Yilin Wang
Summary: Carbon quantum dots (CQDs) prepared from trifolium leaves were used to construct a double signal probe for the detection of ellagic acid (EA). The probe showed sensitive analysis, high selectivity, and feasibility in commercial cosmetics analysis.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Materials Science, Biomaterials
Yi-Fan Wang, Meng-Meng Pan, Yong-Li Song, Zhi Li, Le Wang, Ming Jiang, Xu Yu, Li Xu
Summary: This study successfully synthesized a versatile nitrogen-doped silicon quantum dot (N-SiQD) and demonstrated its potential applications in bacterial imaging, synthesis of nanocomposites, and antimicrobial properties.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Chemistry, Physical
Ha Trang Nguyen, Thanh Thao Tran, Vishwa Bhatt, Manjeet Kumar, Ju-Hyung Yun
Summary: Hybrid nanostructures composed of quantum dots and metal nanoparticles have unique optical properties, and can be used to control photoluminescence in optoelectronic applications. By controlling the composition and size of the structure, the interaction between excitons and plasmon can be investigated, and the power conversion efficiency of silicon solar cells can be improved.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Spectroscopy
Qin Ouyang, Yongcun Yang, Shujat Ali, Li Wang, Huanhuan Li, Quansheng Chen
Summary: The study developed a rapid, sensitive, and specific aptasensor based on FRET for detecting Staphylococcus aureus in food. Under optimized conditions, there was a significant linear correlation between fluorescence intensity and S. aureus concentration, demonstrating high detection sensitivity and accuracy.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Biophysics
Jelena D. Pajovic, Radovan J. Dojcilovic, Slavka Kascakova, Matthieu Refregiers, Dusan K. Bozanic, Vladimir Djokovic
Summary: Functionalized gold nanoparticles using amino acid tryptophan and vitamin riboflavin showed enhanced resonance energy transfer (RET) efficiency, leading to a different photobleaching dynamics compared to molecules in solution. This effect was utilized for detection of the nanoparticles within autofluorescent biological material.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Biochemical Research Methods
Mehavesh K. Hameed, Javad B. M. Parambath, Sofian M. Kanan, Ahmed A. Mohamed
Summary: Biocompatible and luminescent nanostructures synthesized by capping gold-carbon nanoparticles with amino acids were successfully utilized for the quantitative estimation of the drug ranitidine. The method showed a detection limit of 0.174, 0.56, and 0.332 mu M for different amino acid bioconjugates, and was also successful in quantifying ranitidine in spiked serum samples. The study demonstrates the potential of this approach for sensitive and accurate drug quantification.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Materials Science, Multidisciplinary
Haiyan Liu, Chenyu Li, Jing Li, Yuqing Cheng, Junfang Zhao, Jianing Chen, Mengtao Sun
Summary: In this paper, the physical mechanism of surface plasmons (SPs), fluorescence, fluorescence resonance energy transfer (FRET), and plasmon-enhanced FRET (PE-FRET) is reviewed. Furthermore, the latest research on PE-FRET in different systems, such as core-shell structure, nanorod, ultrathin film, etc., is highlighted. These PE-FRET properties have potential applications in optoelectronic devices, solar cells, biodetectors, sensors, etc. This work provides guidance for the applications of combining plasmonic effect and FRET.
APPLIED MATERIALS TODAY
(2023)
Article
Chemistry, Multidisciplinary
Chiara Argentati, Francesco Morena, Chiara Fontana, Ilaria Tortorella, Carla Emiliani, Loredana Latterini, Giulia Zampini, Sabata Martino
Summary: The study investigated the effects of chemically functionalized nanoparticles on human stem cells, finding that the stem cells exhibited similar growth and viability levels on all types of nanoparticles with morphological changes observed. Gold nanoseeds nanoparticles showed slight genotoxic effects on stem cells but did not impact their behavior.
Article
Chemistry, Analytical
Lin Liu, Xiaotong Li, Hua Zhang, Hongda Chen, Murad M. A. Abualrejal, Daqian Song, Zhenxin Wang
Summary: A six-in-one peptide functionalized upconversion@polydopamine nanoparticle-based ratiometric fluorescence sensing platform has been developed for real-time monitoring of anticancer efficacy through detection of caspase-3 activity. The platform shows high sensitivity and real-time feedback capability, allowing successful evaluation of tumor response to various treatment modalities.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Nguyen Tran Truc Phuong, Viet-Duc Phung, Thu Bao Nguyen Le, Tran Chi, Bui Thi Thu Hien, Le Hong Tho, Ngoc Xuan Dat Mai, Thang Bach Phan, Nhu Hoa Thi Tran, Heongkyu Ju
Summary: This study develops ultrahigh-sensitive sensors for cyanide monitoring using chemically synthesized Au-core-Ag-shell hybrid nanomaterials. Colorimetric sensors and fiber optical sensors are prepared, which rely on the formation of the Ag/Au cyanocomplex upon cyanide injection. The colorimetric sensor provides a lower detectable cyanide concentration compared to the fiber-based sensor.
Review
Chemistry, Multidisciplinary
Mariam Abdulaziz M. Tarkistani, Varsha Komalla, Veysel Kayser
Summary: This review discusses the synthesis methods of iron-gold-based hybrid nanostructures, various forms of hybrids, and their potential applications as multifunctional nanoprobes.
Review
Chemistry, Multidisciplinary
Clemence Cheignon, Ali A. Kassir, Lohona K. Soro, Loic J. Charbonniere
Summary: This article reviews the application of lanthanide complexes in spectroscopy. By utilizing the antenna effect brought by organic ligands, the low brightness caused by forbidden Ln electronic transitions can be overcome. Furthermore, the design progress of nano-objects with multiple lanthanide ions and their spectroscopic properties are discussed.
Article
Biochemistry & Molecular Biology
Tsung-Han Ho, Chien-Hsin Yang, Zheng-En Jiang, Hung-Yin Lin, Yih-Fung Chen, Tzong-Liu Wang
Summary: In this study, a facile and effective method was used to coat mesoporous silica shell on ligand-free upconversion nanoparticles. Two types of mesoporous silica-coated UCNPs with different emissions were successfully synthesized. Photosensitizers were loaded into the mesoporous silica shell, and the UCNP@mSiO(2)/PS nanocarrier system showed enhanced ROS generation and therapeutic efficacy in PDT.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Xiaoning Li, Huirui Zhu, Zihan Xing, Tao Gong, Meining Li, Dan Su, Wenting Liang, Rui Guo
Summary: A novel multifunctional graphene oxide nano drug carrier (GO@LM-SP-FA) was constructed by connecting a linear maltodextrin polymer (LM-SP) and folic acid (FA) to the surface of graphene oxide (GO) nanoparticles. The GO@LM-SP-FA exhibited excellent photothermal conversion efficiency, double-targeted drug delivery and NIR/pH triggered drug release. The combination of FA cancer cell targeting showed significant cancer-killing efficiency in HeLa and MCF-7 cells. This novel nano-drug carrier has potential practical application value in the treatment of cancer, especially in cervical cancer.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Chen Luo, Xiaoxiao Chen, Pu Li, Chaobiao Huang
Summary: A photoelectrochemical sensor for methionine detection was developed based on the aggregation of gold nanoparticles induced by DNA bio-dots. The sensor utilized CS-GSH-CuNCs/TiO2 NPs as the photoelectric conversion element and AuNPs as the specific recognition element. The sensor showed good linearity in detecting methionine concentration and had a low limit of detection.
Article
Chemistry, Analytical
Heng Zou, Wanqing Yue, Wai-Kin Yu, Dandan Liu, Chi-Chun Fong, Jianlong Zhao, Mengsu Yang
ANALYTICAL CHEMISTRY
(2015)
Article
Materials Science, Biomaterials
Changqing Yi, Lei Liu, Cheuk-Wing Li, Jinchao Zhang, Mengsu Yang
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2015)
Review
Chemistry, Analytical
Md Kowsar Alam, Emmanuel Koomson, Heng Zou, Changqing Yi, Cheuk-Wing Li, Tao Xu, Mengsu Yang
ANALYTICA CHIMICA ACTA
(2018)
Article
Nanoscience & Nanotechnology
Dandan Liu, Changqing Yi, Chi-Chun Fong, Qinghui Jin, Zuankai Wang, Wai-Kin Yu, Dong Sun, Jianlong Zhao, Mengsu Yang
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
(2014)
Article
Biochemistry & Molecular Biology
Tianzhong Li, Jianbo Yue, Linfeng Huang, Mengsu Yang
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2019)
Article
Chemistry, Multidisciplinary
Chen Liang, Xinglin Zhang, Mengsu Yang, Xiaochen Dong
ADVANCED MATERIALS
(2019)
Article
Biophysics
Xiuping Li, Tianyu Cui, Wenxian Zhang, Ziran Zhai, Feixuan Wu, Yuwei Zhang, Mengsu Yang, Wenying Zhong, Wanqing Yue
COLLOIDS AND SURFACES B-BIOINTERFACES
(2020)
Article
Engineering, Biomedical
Hualin Li, Peng Liu, Renardi Gunawan, Zemenu Mengistie Simeneh, Chen Liang, Xi Yao, Mengsu Yang
Summary: The development of liquid marbles coated with iron oxide nanocubes allows for homogeneous heating with an alternating magnetic field, achieving temperatures up to 86 degrees C. By tuning the power of the AMF, the liquid marbles can be heated to desired temperatures in controllable patterns. Furthermore, the unique magnetothermal properties of these liquid marbles enable multicenter and selective heating, showing potential applications in areas such as biosensor technology and theranostics.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Biotechnology & Applied Microbiology
Xuandi Lai, Xinran Geng, Mengqing Li, Mengxiong Tang, Qiong Liu, Mengsu Yang, Lin Shen, Yu Zhu, Shubin Wang
Summary: The study developed a drug delivery system based on PEG-modified PLGA, named DCNP, which effectively overcomes tumor multidrug resistance. Through in vitro and in vivo experiments, it was found that DCNPs release drugs under high GSH concentration, enhance the toxicity to MDR cancer cells, and show better biocompatibility and anti-tumor efficacy.
Article
Multidisciplinary Sciences
Heng Zou, Zihan Yang, Yuen-San Chan, Sung-king Au Yeung, Md Kowsar Alam, Tongxu Si, Tao Xu, Mengsu Yang
Summary: This research investigated the gene expression and mechanical properties associated with EMT at the single-cell level in non-small cell lung cancer fingers. The study found that leader cells in the cancer fingers were more elastic and less sticky than follower cells. SNAIL and VIM were identified as two key genes that positively correlated with leader cell phenotypes and controlled cancer finger formation.
Article
Chemistry, Multidisciplinary
Zihan Yang, Zhihang Zhou, Tongxu Si, Zhengdong Zhou, Li Zhou, Y. Rebecca Chin, Liang Zhang, Xinyuan Guan, Mengsu Yang
Summary: Cancer metastasis is a major cause of cancer-related death, and it is characterized by excessive extracellular matrix deposition and increased stiffness in solid tumors. The confined migration of tumor cells in these conditions plays a crucial role in metastasis, but inhibitors specifically targeting this type of migration are rare. In this study, a microfluidic chip was designed to screen for drugs that can effectively inhibit confined migration of cancer cells. By applying this chip, three novel inhibitors of confined migration, MA-5, SB-705498, and diphenyleneiodonium chloride, were discovered in multiple cancer types. The mechanisms of action of these inhibitors were found to be targeting mitochondria, actin polymerization, and cell viability, respectively. Overall, a high-throughput microfluidic platform for screening drugs targeting confined migration was established, and three effective inhibitors were identified.
Review
Engineering, Biomedical
Wenxiu Li, Zhihang Zhou, Xiaoyu Zhou, Bee Luan Khoo, Renardi Gunawan, Y. Rebecca Chin, Liang Zhang, Changqing Yi, Xinyuan Guan, Mengsu Yang
Summary: Decades of engineering efforts have led to the advancement of in vitro cancer models for drug discovery and cancer biology research. However, the creation of preclinical models that fully replicate the tumor microenvironment remains challenging. Recent progress in engineering techniques has allowed the development of new in vitro models, such as spheroids, organoids, and tumor-on-a-chip, which can accurately predict drug responses and recreate complex tumor microenvironments. These biomimetic 3D tumor models are valuable for understanding cancer biology and accelerating the development of new anticancer therapies while reducing the use of animals.
ADVANCED HEALTHCARE MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Xulin Xie, Jiao Zhai, Xiaoyu Zhou, Zhengjun Guo, Pui-Chi Lo, Guangyu Zhu, Kannie W. Y. Chan, Mengsu Yang
Summary: This article introduces the basic principles and important features of magnetic nanoparticle imaging (MPI), as well as the latest research progress in optimizing the performance of MPI tracers. The applications of MPI in investigating vascular abnormalities, cancer, and the latest developments and challenges in clinical translation are also discussed.
ADVANCED MATERIALS
(2023)
Article
Multidisciplinary Sciences
Xudong Liu, Ying Ni, Dandan Wang, Silin Ye, Mengsu Yang, Xuan Sun, Anskar Yu Hung Leung, Runsheng Li
Summary: In this study, Oxford Nanopore Technologies (ONT) sequencing was used to analyze DNA methylation in zebrafish kidney marrow. The research revealed that blood contamination affects the quality of sequencing data and alters methylation patterns. Compared to whole-genome bisulfite sequencing (WGBS), ONT-based methylation profiling covers more CpG sites and exhibits more even genomic coverage. The results also showed a high correlation between ONT methylation calling and WGBS results when using shared sites. This study establishes a comprehensive methylation profile for zebrafish kidney marrow, laying the foundation for further research on epigenetic regulation and targeted therapies for hematopoietic disorders.
Article
Chemistry, Multidisciplinary
Jingyun Jiang, Jinsheng Zhan, Wanqing Yue, Mengsu Yang, Changqing Yi, Cheuk-Wing Li
