Utility of Physiologically Based Modeling and Preclinical In Vitro/In Vivo Data to Mitigate Positive Food Effect in a BCS Class 2 Compound

Title
Utility of Physiologically Based Modeling and Preclinical In Vitro/In Vivo Data to Mitigate Positive Food Effect in a BCS Class 2 Compound
Authors
Keywords
amorphous formulation, food effects, physiologically based pharmacokinetic (PBPK) modeling, population simulation, precipitation
Journal
AAPS PHARMSCITECH
Volume 14, Issue 3, Pages 1255-1266
Publisher
American Association of Pharmaceutical Scientists (AAPS)
Online
2013-08-17
DOI
10.1208/s12249-013-0018-2

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