Orthogonal High-Throughput Thermal Scanning Method for Rank Ordering Protein Formulations

Hazardous Alcohol Consumption Is a Major Factor in Male Premature Mortality in a Typical Russian City: Prospective Cohort Study 2003–2009

(2012) Susannah Tomkins et al.   PLoS One

First-order rate-determining aggregation mechanism of p53 and its implications

(2012) G. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetic mechanism of p53 oncogenic mutant aggregation and its inhibition

(2012) R. Wilcken et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predicting solution aggregation rates for therapeutic proteins: Approaches and challenges

(2011) Christopher J. Roberts et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Predicting accelerated aggregation rates for monoclonal antibody formulations, and challenges for low-temperature predictions

(2011) Rebecca K. Brummitt et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Conformational stability and aggregation of therapeutic monoclonal antibodies studied with ANS and Thioflavin T binding

(2011) Veysel Kayser et al.   mAbs

Coupling of Aggregation and Immunogenicity in Biotherapeutics: T- and B-Cell Immune Epitopes May Contain Aggregation-Prone Regions

(2011) Sandeep Kumar et al.   PHARMACEUTICAL RESEARCH

Computational Design and Biophysical Characterization of Aggregation-Resistant Point Mutations for γD Crystallin Illustrate a Balance of Conformational Stability and Intrinsic Aggregation Propensity

(2010) Erinc Sahin et al.   BIOCHEMISTRY

Formulation Development of Therapeutic Monoclonal Antibodies Using High-Throughput Fluorescence and Static Light Scattering Techniques: Role of Conformational and Colloidal Stability

(2010) Deborah S. Goldberg et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Searching for conditions to form stable protein oligomers with amyloid-like characteristics: The unexplored basic pH

(2009) Basir Ahmad et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

High throughput thermostability screening of monoclonal antibody formulations

(2009) Feng He et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Multi-variate approach to global protein aggregation behavior and kinetics: Effects of pH, NaCl, and temperature for α-chymotrypsinogen A

(2009) Yi Li et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

High-Throughput Thermal Scanning: A General, Rapid Dye-Binding Thermal Shift Screen for Protein Engineering

(2009) Jason J. Lavinder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amyloidogenesis of Natively Unfolded Proteins

(2008) Vladimir Uversky   Current Alzheimer Research

Extrinsic Fluorescent Dyes as Tools for Protein Characterization

(2008) Andrea Hawe et al.   PHARMACEUTICAL RESEARCH