Development and Characterization of Quantitative, High-Throughput-Compatible Assays for Proteolytic Degradation of Glucagon

Peptidic inhibitors of insulin-degrading enzyme with potential for dermatological applications discovered via phage display

(2018) Caitlin N. Suire et al.   PLoS One

The New Biology and Pharmacology of Glucagon

(2017) T. D. Müller et al.   PHYSIOLOGICAL REVIEWS

Fluorescence polarization assays in high-throughput screening and drug discovery: a review

(2016) Matthew D Hall et al.   Methods and Applications in Fluorescence

Selective Targeting of Extracellular Insulin-Degrading Enzyme by Quasi-Irreversible Thiol-Modifying Inhibitors

(2015) Samer O. Abdul-Hay et al.   ACS Chemical Biology

Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones

(2014) Juan Pablo Maianti et al.   NATURE

Optimization of Peptide Hydroxamate Inhibitors of Insulin-Degrading Enzyme Reveals Marked Substrate-Selectivity

(2013) Samer O. Abdul-Hay et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chelator Fragment Libraries for Targeting Metalloproteinases

(2010) Arpita Agrawal et al.   ChemMedChem

Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of Insulin

(2010) Malcolm A. Leissring et al.   PLoS One

Development of monoclonal antibodies and quantitative ELISAs targeting insulin-degrading enzyme

(2009) Anthony DelleDonne et al.   Molecular Neurodegeneration

Small-Molecule Activators of Insulin-Degrading Enzyme Discovered through High-Throughput Compound Screening

(2009) Christelle Cabrol et al.   PLoS One

Molecular basis for the thiol sensitivity of insulin-degrading enzyme

(2008) M. Neant-Fery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA