HIV-1 Protein Tat1–72 Impairs Neuronal Dendrites via Activation of PP1 and Regulation of the CREB/BDNF Pathway

HIV-1-associated neurocognitive disorder: epidemiology, pathogenesis, diagnosis, and treatment

(2017) Christian Eggers et al.   JOURNAL OF NEUROLOGY

Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models

(2016) Verónica Martínez-Cerdeño   Developmental Neurobiology

Curcumin inhibits HIV-1 by promoting Tat protein degradation

(2016) Amjad Ali et al.   Scientific Reports

Protein phosphatase 1 is a key player in nuclear events

(2015) Sandra Rebelo et al.   CELLULAR SIGNALLING

Cocaine self-administration enhances excitatory responses of pyramidal neurons in the rat medial prefrontal cortex to human immunodeficiency virus-1 Tat

(2015) Wesley N. Wayman et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Protein Phosphatase-1 Inhibitor-2 Is a Novel Memory Suppressor

(2015) H. Yang et al.   JOURNAL OF NEUROSCIENCE

Prevalence of HIV-associated neurocognitive disorders in the Multicenter AIDS Cohort Study

(2015) Ned Sacktor et al.   NEUROLOGY

Agonist binding to the NMDA receptor drives movement of its cytoplasmic domain without ion flow

(2015) Kim Dore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting RPTPσ with lentiviral shRNA promotes neurites outgrowth of cortical neurons and improves functional recovery in a rat spinal cord contusion model

(2014) Heng-Xing Zhou et al.   BRAIN RESEARCH

Autophagy Restricts HIV-1 Infection by Selectively Degrading Tat in CD4+T Lymphocytes

(2014) Sophie Sagnier et al.   JOURNAL OF VIROLOGY

Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND)

(2014) Vasudev R Rao et al.   AIDS Research and Therapy

HIV-1 Tat protein variants: Critical role for the cysteine region in synaptodendritic injury

(2013) Sarah J. Bertrand et al.   EXPERIMENTAL NEUROLOGY

Synaptic NMDA receptor stimulation activates PP1 by inhibiting its phosphorylation by Cdk5

(2013) Hailong Hou et al.   JOURNAL OF CELL BIOLOGY

Molecular mechanisms of dendrite stability

(2013) Anthony J. Koleske   NATURE REVIEWS NEUROSCIENCE

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

(2013) Bai Lu et al.   NATURE REVIEWS NEUROSCIENCE

Stress and trauma: BDNF control of dendritic-spine formation and regression

(2013) M.R. Bennett et al.   PROGRESS IN NEUROBIOLOGY

Synaptic Dysfunction in the Hippocampus Accompanies Learning and Memory Deficits in Human Immunodeficiency Virus Type-1 Tat Transgenic Mice

(2012) Sylvia Fitting et al.   BIOLOGICAL PSYCHIATRY

HIV-1 Tat Triggers Nuclear Localization of ZO-1 via Rho Signaling and cAMP Response Element-Binding Protein Activation

(2012) Y. Zhong et al.   JOURNAL OF NEUROSCIENCE

Human Immunodeficiency Virus Type 1 Alters Brain-Derived Neurotrophic Factor Processing in Neurons

(2012) A. Bachis et al.   JOURNAL OF NEUROSCIENCE

Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway

(2012) Samir Nath et al.   JOURNAL OF NEUROVIROLOGY

Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures

(2012) Angela H. Shin et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

HIV-1 decreases the levels of neurotrophins in human lymphocytes

(2011) Valeriya Avdoshina et al.   AIDS

HIV-1 Tat Protein Promotes Neuronal Dysfunction through Disruption of MicroRNAs

(2011) J. Robert Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Tat-Induced Microgliosis and Synaptic Damage via Interactions between Peripheral and Central Myeloid Cells

(2011) Shao-Ming Lu et al.   PLoS One

Interactive Comorbidity between Opioid Drug Abuse and HIV-1 Tat

(2010) Sylvia Fitting et al.   AMERICAN JOURNAL OF PATHOLOGY

CREB: a multifaceted regulator of neuronal plasticity and protection

(2010) Kensuke Sakamoto et al.   JOURNAL OF NEUROCHEMISTRY

CREB's control of intrinsic and synaptic plasticity: implications for CREB-dependent memory models

(2010) Eva Benito et al.   TRENDS IN NEUROSCIENCES

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Human Immunodeficiency Virus Protein Tat Induces Synapse Loss via a Reversible Process That Is Distinct from Cell Death

(2008) H. J. Kim et al.   JOURNAL OF NEUROSCIENCE

NMDA Receptor Activation by HIV-Tat Protein Is Clade Dependent

(2008) W. Li et al.   JOURNAL OF NEUROSCIENCE