Large inter- and intra-case variability of first generation tau PET ligand binding in neurodegenerative dementias

α-Synuclein Oligomers Induce a Unique Toxic Tau Strain

(2018) Diana L. Castillo-Carranza et al.   BIOLOGICAL PSYCHIATRY

A Highly Selective and Specific PET Tracer for Imaging of Tau Pathologies

(2018) Wei Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Tau PET imaging predicts cognition in atypical variants of Alzheimer's disease

(2017) Jeffrey S. Phillips et al.   HUMAN BRAIN MAPPING

Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer’s Disease with Positron Emission Tomography

(2017) Luca C. Gobbi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain

(2017) Sneha Narasimhan et al.   JOURNAL OF NEUROSCIENCE

Tau-imaging in neurodegeneration

(2017) Gérard N. Bischof et al.   METHODS

Tau PET imaging: present and future directions

(2017) Laure Saint-Aubert et al.   Molecular Neurodegeneration

The tau positron-emission tomography tracer AV-1451 binds with similar affinities to tau fibrils and monoamine oxidases

(2017) Céline Vermeiren et al.   MOVEMENT DISORDERS

Frontotemporal dementia with the V337M MAPT mutation

(2017) Salvatore Spina et al.   NEUROLOGY

Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain

(2017) Kok Pin Ng et al.   Alzheimers Research & Therapy

Candidate PET Radioligand Development for Neurofibrillary Tangles: Two Distinct Radioligand Binding Sites Identified in Postmortem Alzheimer’s Disease Brain

(2016) Lisheng Cai et al.   ACS Chemical Neuroscience

Characterization of tau positron emission tomography tracer [ 18 F]AV-1451 binding to postmortem tissue in Alzheimer's disease, primary tauopathies, and other dementias

(2016) Kerstin Sander et al.   Alzheimers & Dementia

18F-AV-1451 tau PET imaging correlates strongly with tau neuropathology inMAPTmutation carriers

(2016) Ruben Smith et al.   BRAIN

Regional profiles of the candidate tau PET ligand18F-AV-1451 recapitulate key features of Braak histopathological stages

(2016) Adam J. Schwarz et al.   BRAIN

Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease

(2016) Rik Ossenkoppele et al.   BRAIN

Tau imaging with [18F]THK-5351 in progressive supranuclear palsy

(2016) A. Ishiki et al.   EUROPEAN JOURNAL OF NEUROLOGY

Preclinical Characterization of 18F-MK-6240, a Promising PET Tracer for In Vivo Quantification of Human Neurofibrillary Tangles

(2016) E. D. Hostetler et al.   JOURNAL OF NUCLEAR MEDICINE

Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo

(2016) Sarah K. Kaufman et al.   NEURON

PET Imaging of Tau Deposition in the Aging Human Brain

(2016) Michael Schöll et al.   NEURON

Dynamic PET Measures of Tau Accumulation in Cognitively Normal Older Adults and Alzheimer’s Disease Patients Measured Using [18F] THK-5351

(2016) Samuel N. Lockhart et al.   PLoS One

[18F]AV-1451 PET in behavioral variant frontotemporal dementia due to MAPT mutation

(2016) W. Richard Bevan Jones et al.   Annals of Clinical and Translational Neurology

An autoradiographic evaluation of AV-1451 Tau PET in dementia

(2016) Val J. Lowe et al.   Acta Neuropathologica Communications

Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue

(2015) Marta Marquié et al.   ANNALS OF NEUROLOGY

Tau positron emission tomographic imaging in aging and early Alzheimer disease

(2015) Keith A. Johnson et al.   ANNALS OF NEUROLOGY

[18F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer’s disease

(2015) Ryuichi Harada et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease

(2015) R. Harada et al.   JOURNAL OF NUCLEAR MEDICINE

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

(2015) Zhen Zhao et al.   NATURE NEUROSCIENCE

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

Visualization of regional tau deposits using 3H-THK5117 in Alzheimer brain tissue

(2015) Laetitia Lemoine et al.   Acta Neuropathologica Communications

Tau PET Imaging in Alzheimer’s Disease

(2014) Nobuyuki Okamura et al.   Current Neurology and Neuroscience Reports

[18F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease

(2013) Chun-Fang Xia et al.   Alzheimers & Dementia

Novel 18F-Labeled Arylquinoline Derivatives for Noninvasive Imaging of Tau Pathology in Alzheimer Disease

(2013) N. Okamura et al.   JOURNAL OF NUCLEAR MEDICINE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

A comparative clinical, pathological, biochemical and genetic study of fused in sarcoma proteinopathies

(2011) T. Lashley et al.   BRAIN