Article
Chemistry, Multidisciplinary
Saeed Yazdanseta, Kosar Yasin, Moslem Setoodehkhah, Mohammad Ghanbari, Elham Fadaee
Summary: A novel water-soluble Salen type Cu(II) Schiff base complex functionalized silica-coated magnetite nanoparticles have been synthesized and characterized. The nanocatalyst showed excellent dispersibility in water and exhibited efficient catalytic activity for the reaction of dimedone, aromatic aldehydes, and malononitrile, producing high yields of 2-amino-4H-chromene derivatives.
RESEARCH ON CHEMICAL INTERMEDIATES
(2022)
Article
Chemistry, Multidisciplinary
Sandip P. P. Patil, Sachinkumar K. K. Shinde, Vikram M. M. Desai, Arvind A. A. Pawar, Jeevan S. S. Ghodake, Suresh S. S. Patil
Summary: In this study, a magnetically separable heterogeneous nickel-zinc ferrite catalyst was successfully synthesized and used for the synthesis of 2-amino-4H-chromene derivatives via a one-pot, three-component condensation reaction. The catalyst exhibited several advantages, such as green reaction conditions, easy work-up, short reaction time, high product yields, chromatography-free purification, and efficient catalytic activity. Importantly, the catalyst could be easily recovered from the reaction mixture using an external magnet and reused multiple times without significant loss of activity.
RESEARCH ON CHEMICAL INTERMEDIATES
(2023)
Article
Chemistry, Inorganic & Nuclear
Dikin Patel, Komal A. Trivedi, Himanshu Srivastava, Sanjeev R. Kane, Chetan K. Modi
Summary: In this study, we fabricated a novel nano-catalyst FeNPs/DETA@rGO with a dual activation mechanism. The catalyst exhibits excellent characteristics in terms of both base and acid properties, enabling efficient catalysis of carbon-carbon bond formation. Moreover, the catalyst showed good stability even after multiple cycles of recycling.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Biochemistry & Molecular Biology
Heba A. H. Elshemy, Mohamed A. Zaki, Ayman M. Mahmoud, Shabana Khan, Amar G. Chittiboyina, Aliaa M. Kamal
Summary: A series of 4-aryl-2-amino-4H chromene derivatives were synthesized and evaluated for their cytotoxic activity, showing potential anticancer effects against various cancer cell lines, especially breast cancer and non-small lung cancer cell lines.
BIOORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Mona Maddahi, Sakineh Asghari, Ghasem Firouzzadeh Pasha
Summary: A novel method for the synthesis of 2-amino-4H-chromene derivatives via a three-component reaction has been reported. The reaction involved the use of 2,4-dihydroxybenzophenone, malononitrile, and aromatic aldehydes, and was catalyzed by triethylamine in ethanol as a green solvent. The synthesized products were characterized using various analytical techniques. The simplicity of the procedure, green reaction conditions, short reaction time, and easy separation of the products make it an interesting alternative to other reported approaches. The synthesized compounds showed significant antibacterial and antioxidant activities, with compound 4b demonstrating the highest activities.
RESEARCH ON CHEMICAL INTERMEDIATES
(2023)
Article
Chemistry, Organic
Shaily Sharma, Mahesh Meena, Himanshu Sharma, Dinesh Kumar Yadav, Atul Tiwari, Ved Prakash Verma
Summary: In this study, 17 examples of 2-Amino-3-cyano-4H-chromene derivatives were prepared via a one-pot three components domino Knoevenagel-Michael condensation reaction. The reaction was conducted under ultrasound irradiation using Fe3O4-supported sulfonated graphene oxide as a green and magnetically separable nanocatalyst. The synthesis protocol showed high atom economy, excellent yields, and other advantages such as short reaction time and recyclability of the catalyst. In-silico studies were conducted to analyze the docking interactions of the compounds with selected proteins, and ADME and toxicity analysis were also performed.
SYNTHETIC COMMUNICATIONS
(2022)
Letter
Chemistry, Multidisciplinary
Ali Maleki, Zoleikha Hajizadeh, Kobra Valadi
Summary: The synthesis and characterization of mica/Fe3O4 nanocomposite have been successfully achieved, showing environmentally friendly, low cost, and non-toxic properties. This nanocomposite serves as an efficient heterogeneous nanocatalyst in the synthesis of organic pharmaceutical compounds, with the advantage of easy separation with an external magnet and multiple reuse cycles.
GREEN CHEMISTRY LETTERS AND REVIEWS
(2021)
Article
Multidisciplinary Sciences
Reza Eivazzadeh-Keihan, Shahrzad Bahrami, Mostafa Ghafori Gorab, Zahra Sadat, Ali Maleki
Summary: By employing the naturally-originated molecule of creatine, an environmentally benign magnetic organometallic nanobiocatalyst was successfully prepared. The catalyst was characterized using various techniques and found to have a size distribution of 70 nm. It exhibited high catalytic activity in a single-step reaction, producing a variety of derivatives with short reaction times and high yields.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Multidisciplinary
Soukaina Chehab, Youssef Merroun, Achraf Elhallaoui, Tourya Ghailane, Said Boukhris, Taoufiq Guedira, Rachida Ghailane, Abdelaziz Souizi
Summary: This study presents a simple, efficient, and eco-friendly synthesis method for 2-amino-4H-chromene derivatives using a Knoevenagel condensation reaction between various aromatic aldehydes and active methylene compounds. The reaction is catalyzed by cadmium chloride-modified mono-ammonium phosphate fertilizer (MAP), and the products are obtained with excellent yields in a short reaction time.
JOURNAL OF CHEMICAL SCIENCES
(2023)
Article
Chemistry, Organic
Krishnappa B. B. Badiger, Kantharaju Kamanna, Ramesha Hanumanthappa, K. S. Devaraju, G. Giddaerappa, Lokesh Koodlur Sannegowda
Summary: In this work, an efficient one-pot three-component synthesis of 2-amino-4H-chromene was achieved through microwave irradiation using a water extract of orange fruit peel ash as a catalyst. The synthesized derivatives showed antioxidant activities and good oxidation and reduction potential. This method provides an eco-friendly and cost-effective approach for the synthesis of 2-amino-4H-chromene derivatives.
POLYCYCLIC AROMATIC COMPOUNDS
(2023)
Article
Chemistry, Multidisciplinary
Hossein Rouh, Yao Tang, Sai Zhang, Ahmed I. M. Ali, Kazimierz Surowiec, Daniel Unruh, Guigen Li
Summary: This work introduces a strategy for synthesizing functionalized 4H-chromene derivatives through a [4 + 2] cycloaddition reaction, resulting in several products under specific conditions. The products can be easily purified using Group-Assisted Purification (GAP) technology, avoiding traditional separation methods. The absolute configuration was determined by X-ray structure analysis.
Article
Chemistry, Physical
Shoaib Muhammad, Firdous Imran Ali, Muhammad Naveed Javed, Agha Arsalan Wasim, Ahmed Bari, Faisal Rafique, Muhammad Amjad Ilyas, Kashif Riaz, Syed Junaid Mahmood, Amir Ahmed, Imran Ali Hashmi
Summary: This study focuses on the influence of the aggregation behavior of RTILs on catalytic activity, with the synthesis of new RTILs and experimentation showing improved catalytic performance in one specific compound. Various experiments were conducted to explore the mechanism of aggregation in RTILs.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Organic
Shuang Wang, Jun-Jie Lin, Xin Cui, Jing-Peng Li, Chao Huang
Summary: A one-pot method has been developed for the selective synthesis of two isomers without a catalyst, forming multiple chemical bonds in mild conditions with high atom economy. The selectivity is controlled by thermodynamics and kinetics, with discussions on the reasons for the transformation of the two structures.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Sandip P. Patil, Sachinkumar K. Shinde, Suresh S. Patil
Summary: In this study, coconut endocarp shell was converted into a valuable non-conventional catalyst called CESA. The prepared CESA was characterized and found to exhibit high catalytic efficiency and excellent yield of products in a one-pot reaction. Furthermore, the CESA catalyst showed good stability after multiple recycling.
RESEARCH ON CHEMICAL INTERMEDIATES
(2022)
Article
Chemistry, Organic
Satish Kumar Burra, Vaikunta Rao Lakinani, Raghunadh Akula, Chiranjeevi Yankkanti
Summary: A novel and green strategy for the construction of biologically relevant substituted indolyl-4H-chromenes scaffolds is reported, using L-proline as a catalyst and water as a promoter solvent. This catalytic system offers wider applicability, shorter reaction times, and high yields, making it an ideal condition for green chemistry.
SYNTHETIC COMMUNICATIONS
(2024)
Article
Biochemistry & Molecular Biology
Santosh Y. Khatavi, K. Kantharaju
Summary: The study developed a green protocol using solvent media derived from agricultural waste, eliminating the need for chemical entities in synthesizing peptide bonds. The quality and purity of the final product were analyzed using various spectroscopic and analytical techniques.
PROTEIN AND PEPTIDE LETTERS
(2021)
Article
Engineering, Environmental
Yamanappagouda Amaregouda, Kantharaju Kamanna, Tilak Gasti, Vijay Kumbar
Summary: In this study, CuO nanorods were biogenically prepared and surface modified with L-alanine amino acid, using microwave irradiation. The functionalized CuO nanorods were then incorporated into polyvinyl alcohol/carboxymethyl cellulose films, resulting in improvements in tensile strength, UV shielding ability, and barrier to water vapors. The films also exhibited antioxidant, antibacterial, and antifungal activities, while showing minimal cytotoxic effects. The developed nanocomposite films have the potential to be used as active food packaging material.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2022)
Article
Chemistry, Physical
Prashant B. Hiremath, Kantharaju Karnanna
Summary: This study utilized agro-waste sourced from banana peel to prepare BPAE catalyst, which was then used for the synthesis of 2-aryl benzimidazole derivatives under ultrasound waves at room temperature. The research established an eco-friendly and novel approach for the synthesis of these molecules, highlighting the advantages of BPAE as an agro-waste-derived catalyst.
CURRENT ORGANOCATALYSIS
(2021)
Article
Polymer Science
Yamanappagouda Amaregouda, Kantharaju Kamanna, Tilak Gasti
Summary: In this study, MgO nanoparticles were prepared using a novel biogenic method and their surface was modified. The inclusion of these modified nanoparticles significantly improved the physico-mechanical properties and other performance of polyvinyl alcohol/carboxymethyl cellulose materials. These nanocomposites also demonstrated good antimicrobial and antioxidant properties, making them promising candidates for food packaging.
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Krishnappa B. Badiger, Giddaerappa, Ramesha Hanumanthappa, Lokesh Koodlur Sannegowda, Kantharaju Kamanna
Summary: An efficient and economical synthesis of pyrano[2,3-c]pyrazoles and pyrazolyl-4H-chromenes using Water Extract of Mango Peel Ash (WEMPA) as a catalyst under microwave irradiation is described. The selected compounds exhibit significant antioxidant activity, making this a sustainable and environmentally friendly method for chemical synthesis.
Article
Food Science & Technology
Yamanappagouda Amaregouda, Kantharaju Kamanna, Aravind Kamath
Summary: The present work focuses on the incorporation of natural anthocyanin and zinc oxide nanoparticles into chitosan/polyvinylalcohol films. These films show pH sensitivity, antioxidant activity, and good cell viability properties. The inclusion of anthocyanin-zinc oxide nanoparticles improves the mechanical resistance, moisture content, and water vapor permeability of the films. The films also exhibit color changes in response to various pH buffer solutions, making them suitable for fish packaging to monitor freshness and fillet deterioration.
ACS FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Krishnappa B. Badiger, Santosh Y. Khatavi, Kantharaju Kamanna
Summary: In this study, an agro-waste-based solvent medium was used to catalyze the synthesis of isoxazole-5(4H)-one derivatives in an eco-friendly and efficient manner. The synthesized compounds exhibited excellent anticancer activity and also showed promising electrochemical behavior and antioxidant properties.
RSC MEDICINAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Kantharaju Kamanna, S. Y. Khatavi, P. B. Hiremath
CURRENT MICROWAVE CHEMISTRY
(2020)
