Synthesis of 4′-Substituted Purine 2′-Deoxynucleosides and Their Activity against Human Immunodeficiency Virus Type 1 and Hepatitis B Virus

Oral Administration of the Nucleoside EFdA (4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine) Provides Rapid Suppression of HIV Viremia in Humanized Mice and Favorable Pharmacokinetic Properties in Mice and the Rhesus Macaque

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Design, synthesis, and biological evaluation of new N 4 -Substituted 2′-deoxy-2′-fluoro-4′-azido cytidine derivatives as potent anti-HBV agents

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4′-modified nucleoside analogs: Potent inhibitors active against entecavir-resistant hepatitis B virus

(2015) Yuki Takamatsu et al.   HEPATOLOGY

Synthesis and Biological Evaluation of 4-Substituted Fluoronucleoside Analogs for the Treatment of Hepatitis B Virus Infection

(2015) Qinghua Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

A review of methods to synthesise 4′-substituted nucleosides

(2014) Mark Betson et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Ten Paths to the Discovery of Antivirally Active Nucleoside and Nucleotide Analogues

(2012) Erik De Clercq   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Synthesis of new 2′-deoxy-2′-fluoro-4′-azido nucleoside analogues as potent anti-HIV agents

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