Investigation of benzylisoquinoline alkaloid biosynthetic pathway and its transcriptional regulation in lotus

Mining of the Uncharacterized Cytochrome P450 Genes Involved in Alkaloid Biosynthesis in California Poppy Using a Draft Genome Sequence

(2017) Kentaro Hori et al.   PLANT AND CELL PHYSIOLOGY

Unraveling Additional O-Methylation Steps in Benzylisoquinoline Alkaloid Biosynthesis in California Poppy (Eschscholzia californica)

(2017) Ratmoyo Purwanto et al.   PLANT AND CELL PHYSIOLOGY

Map-based cloning of the pear gene MYB114 identifies an interaction with other transcription factors to coordinately regulate fruit anthocyanin biosynthesis

(2017) Gaifang Yao et al.   PLANT JOURNAL

Jasmonate-responsive transcription factors regulating plant secondary metabolism

(2016) Meiliang Zhou et al.   BIOTECHNOLOGY ADVANCES

Analysis of Isoquinoline Alkaloid Composition and Wound-Induced Variation in Nelumbo Using HPLC-MS/MS

(2016) Xianbao Deng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Structural and Functional Studies of PavineN-Methyltransferase fromThalictrum flavumReveal Novel Insights into Substrate Recognition and Catalytic Mechanism

(2016) Miguel A. Torres et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of CYP82E21 as a functional nicotine N-demethylase in tobacco flowers

(2016) Verena Liedschulte et al.   PHYTOCHEMISTRY

A Comprehensive Review on Chemical Profiling ofNelumbo Nucifera: Potential for Drug Development

(2016) Bhesh Raj Sharma et al.   PHYTOTHERAPY RESEARCH

Crystal structure of norcoclaurine-6-O-methyltransferase, a key rate-limiting step in the synthesis of benzylisoquinoline alkaloids

(2016) Adeline Y. Robin et al.   PLANT JOURNAL

The basic helix-loop-helix transcription factor BIS2 is essential for monoterpenoid indole alkaloid production in the medicinal plant Catharanthus roseus

(2016) Alex Van Moerkercke et al.   PLANT JOURNAL

Functional Characterization of 4′OMT and 7OMT Genes in BIA Biosynthesis

(2016) Tugba Gurkok et al.   Frontiers in Plant Science

Evolutionary origin of the NCSI gene subfamily encoding norcoclaurine synthase is associated with the biosynthesis of benzylisoquinoline alkaloids in plants

(2016) Sornkanok Vimolmangkang et al.   Scientific Reports

CjbHLH1 homologs regulate sanguinarine biosynthesis in Eschscholzia californica cells

(2015) Yasuyuki Yamada et al.   PLANT AND CELL PHYSIOLOGY

Regulation of the alkaloid biosynthesis by miRNA in opium poppy

(2015) Hatice Boke et al.   PLANT BIOTECHNOLOGY JOURNAL

EjAP2-1, anAP2/ERFgene, is a novel regulator of fruit lignification induced by chilling injury, via interaction withEjMYBtranscription factors

(2015) Jiao-ke Zeng et al.   PLANT BIOTECHNOLOGY JOURNAL

The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway inCatharanthus roseus

(2015) Alex Van Moerkercke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Morphinan biosynthesis in opium poppy requires a P450-oxidoreductase fusion protein

(2015) T. Winzer et al.   SCIENCE

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Comparative Analysis of Antioxidant Activity and Functional Components of the Ethanol Extract of Lotus (Nelumbo nucifera) from Various Growing Regions

(2014) Xu Zhao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Unraveling the Mechanism Underlying the Glycosylation and Methylation of Anthocyanins in Peach

(2014) J. Cheng et al.   PLANT PHYSIOLOGY

The coffee genome provides insight into the convergent evolution of caffeine biosynthesis

(2014) F. Denoeud et al.   SCIENCE

Transcriptional regulation of secondary metabolite biosynthesis in plants

(2013) Barunava Patra et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Neferine, an alkaloid from lotus seed embryo, inhibits human lung cancer cell growth by MAPK activation and cell cycle arrest

(2013) Paramasivan Poornima et al.   BIOFACTORS

Analysis of alkaloids in Lotus (Nelumbo nucifera Gaertn.) leaves by non-aqueous capillary electrophoresis using ultraviolet and mass spectrometric detection

(2013) Tho Chau Minh Vinh Do et al.   JOURNAL OF CHROMATOGRAPHY A

Benzylisoquinoline Alkaloid Metabolism: A Century of Discovery and a Brave New World

(2013) Jillian M. Hagel et al.   PLANT AND CELL PHYSIOLOGY

Evolution of a Complex Locus for Terpene Biosynthesis in Solanum

(2013) Y. Matsuba et al.   PLANT CELL

Morphine Biosynthesis in Opium Poppy Involves Two Cell Types: Sieve Elements and Laticifers

(2013) A. Onoyovwe et al.   PLANT CELL

Characterization of Genes Encoding Granule-Bound Starch Synthase in Sacred Lotus Reveals Phylogenetic Affinity of Nelumbo to Proteales

(2013) Chao Gu et al.   PLANT MOLECULAR BIOLOGY REPORTER

Identification and Comparison of Anti-Inflammatory Ingredients from Different Organs of Lotus Nelumbo by UPLC/Q-TOF and PCA Coupled with a NF-κB Reporter Gene Assay

(2013) Mengge Zhou et al.   PLoS One

Genome of the long-living sacred lotus (Nelumbo nucifera Gaertn.)

(2013) Ray Ming et al.   GENOME BIOLOGY

Redesign of a Dioxygenase in Morphine Biosynthesis

(2012) Weerawat Runguphan et al.   CHEMISTRY & BIOLOGY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Expression of a bacterial feedback-insensitive 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase of the shikimate pathway in Arabidopsis elucidates potential metabolic bottlenecks between primary and secondary metabolism

(2012) Vered Tzin et al.   NEW PHYTOLOGIST

Transcript and metabolite profiling in cell cultures of 18 plant species that produce benzylisoquinoline alkaloids

(2012) Scott C. Farrow et al.   PHYTOCHEMISTRY

Characterization of Three O-Methyltransferases Involved in Noscapine Biosynthesis in Opium Poppy

(2012) T.-T. T. Dang et al.   PLANT PHYSIOLOGY

The basic helix-loop-helix transcription factor CrMYC2 controls the jasmonate-responsive expression of the ORCA genes that regulate alkaloid biosynthesis in Catharanthus roseus

(2011) Hongtao Zhang et al.   PLANT JOURNAL

The Transcription Factor CrWRKY1 Positively Regulates the Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus

(2011) N. Suttipanta et al.   PLANT PHYSIOLOGY

Unusual P450 reactions in plant secondary metabolism

(2010) Masaharu Mizutani et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Supercritical fluid extraction and identification of isoquinoline alkaloids from leaves of Nelumbo nucifera Gaertn

(2010) Juan Xiao et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

The sacred lotus(Nelumbo nucifera)- phytochemical and therapeutic profile

(2010) Pulok K. Mukherjee et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Clustered Transcription Factor Genes Regulate Nicotine Biosynthesis in Tobacco

(2010) Tsubasa Shoji et al.   PLANT CELL

Hepatoprotective and antioxidant activity of ethanolic extracts of edible lotus (Nelumbo nucifera Gaertn.) leaves

(2009) Bo Huang et al.   FOOD CHEMISTRY

Functional characterization of a novel benzylisoquinolineO-methyltransferase suggests its involvement in papaverine biosynthesis in opium poppy (Papaver somniferumL)

(2009) Silke Pienkny et al.   PLANT JOURNAL

Alkaloid Biosynthesis: Metabolism and Trafficking

(2008) Jörg Ziegler et al.   Annual Review of Plant Biology

Evolutionary and cellular webs in benzylisoquinoline alkaloid biosynthesis

(2008) David K Liscombe et al.   CURRENT OPINION IN BIOTECHNOLOGY

Molecular Cloning and Characterization of CYP80G2, a Cytochrome P450 That Catalyzes an Intramolecular C–C Phenol Coupling of (S)-Reticuline in Magnoflorine Biosynthesis, from CulturedCoptis japonicaCells

(2008) Nobuhiro Ikezawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Escape from adaptive conflict after duplication in an anthocyanin pathway gene

(2008) David L. Des Marais et al.   NATURE

Opium poppy and Madagascar periwinkle: model non-model systems to investigate alkaloid biosynthesis in plants

(2008) Peter J. Facchini et al.   PLANT JOURNAL

Enhancement of alkaloid production in opium and California poppy by transactivation using heterologous regulatory factors

(2007) Nestor R. Apuya et al.   PLANT BIOTECHNOLOGY JOURNAL