Overview of the Pathophysiological Implications of Organotins on the Endocrine System

Frontiers in endocrine disruption: Impacts of organotin on the hypothalamus-pituitary-thyroid axis

(2018) Ana Paula Santos-Silva et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Correction to: Parma consensus statement on metabolic disruptors

(2017) Jerrold J. Heindel et al.   Environmental Health

Environmental obesogen tributyltin chloride leads to abnormal hypothalamic-pituitary-gonadal axis function by disruption in kisspeptin/leptin signaling in female rats

(2017) Gabriela C. Sena et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Environmental Pollutant Tributyltin Chloride Disrupts the Hypothalamic-Pituitary-Adrenal Axis at Different Levels in Female Rats

(2016) Eduardo Merlo et al.   ENDOCRINOLOGY

Pharmacological evaluation of the mechanisms involved in increased adiposity in zebrafish triggered by the environmental contaminant tributyltin

(2016) Nafia Ouadah-Boussouf et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tributyltin chloride induces renal dysfunction by inflammation and oxidative stress in female rats

(2016) João V.S. Coutinho et al.   TOXICOLOGY LETTERS

Adult exposure to tributyltin affects hypothalamic neuropeptide Y, Y1 receptor distribution, and circulating leptin in mice

(2016) E. Bo et al.   Andrology

Wpływ tributylocyny na przyjmowanie pokarmu i ekspresję neuropeptydów w mózgu szczurów

(2015) Keyan He et al.   Endokrynologia Polska

Parma consensus statement on metabolic disruptors

(2015) Jerrold J. Heindel et al.   Environmental Health

Peroxisome Proliferator-Activated Receptor   Controls Ingestive Behavior, Agouti-Related Protein, and Neuropeptide Y mRNA in the Arcuate Hypothalamus

(2015) J. T. Garretson et al.   JOURNAL OF NEUROSCIENCE

Tributyltin induces mitochondrial fission through NAD-IDH dependent mitofusin degradation in human embryonic carcinoma cells

(2015) Shigeru Yamada et al.   Metallomics

Tributyltin differentially promotes development of a phenotypically distinct adipocyte

(2015) Shane M. Regnier et al.   Obesity

Accumulation of organotins in seafood leads to reproductive tract abnormalities in female rats

(2015) Priscila L. Podratz et al.   REPRODUCTIVE TOXICOLOGY

Triorganotin compounds - ligands for “rexinoid” inducible transcription factors: Biological effects

(2015) J. Brtko et al.   TOXICOLOGY LETTERS

Tributyltin chloride leads to adiposity and impairs metabolic functions in the rat liver and pancreas

(2015) Bruno D. Bertuloso et al.   TOXICOLOGY LETTERS

Chronic Exposure to Tributyltin Chloride Induces Pancreatic Islet Cell Apoptosis and Disrupts Glucose Homeostasis in Male Mice

(2014) Zhenghong Zuo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Early cellular responses against tributyltin chloride exposure in primary cultures derived from various brain regions

(2014) Sumonto Mitra et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Disruption of thyroid hormone functions by low dose exposure of tributyltin: An in vitro and in vivo approach

(2014) Shruti Sharan et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Perinatal exposure to low doses of tributyltin chloride reduces sperm count and quality in mice

(2013) Jiliang Si et al.   ENVIRONMENTAL TOXICOLOGY

Tributyltin induces oxidative damage, inflammation and apoptosis via disturbance in blood–brain barrier and metal homeostasis in cerebral cortex of rat brain: An in vivo and in vitro study

(2013) Sumonto Mitra et al.   TOXICOLOGY

Tributyltin chloride induced testicular toxicity by JNK and p38 activation, redox imbalance and cell death in sertoli-germ cell co-culture

(2013) Sumonto Mitra et al.   TOXICOLOGY

Perinatal exposure to low doses of tributyltin chloride advances puberty and affects patterns of estrous cyclicity in female mice

(2012) Jiliang Si et al.   ENVIRONMENTAL TOXICOLOGY

Tributyltin Impairs the Reproductive Cycle in Female Rats

(2012) Priscila Lang Podratz et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Organotins: A review of their reproductive toxicity, biochemistry, and environmental fate

(2012) Jones Bernardes Graceli et al.   REPRODUCTIVE TOXICOLOGY

Triphenyltin impairs insulin secretion by decreasing glucose-induced NADP(H) and ATP production in hamster pancreatic β-cells

(2012) Yoshikazu Miura et al.   TOXICOLOGY

Toxicity of organotin compounds: Shared and unshared biochemical targets and mechanisms in animal cells

(2012) Alessandra Pagliarani et al.   TOXICOLOGY IN VITRO

Tributyltin chloride induces ABCA1 expression and apolipoprotein A-I-mediated cellular cholesterol efflux by activating LXRalpha/RXR

(2011) Hongyan Cui et al.   BIOCHEMICAL PHARMACOLOGY

Triorganotin as a compound with potential reproductive toxicity in mammals

(2011) V.S. Delgado Filho et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor gamma to induce adipogenesis in murine 3T3-L1 preadipocytes

(2011) Xia Li et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Obesogen Hypothesis: A Shift of Focus from the Periphery to the Hypothalamus

(2011) Stéphanie Decherf et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Organotins Are Potent Activators of PPARγ and Adipocyte Differentiation in Bone Marrow Multipotent Mesenchymal Stromal Cells

(2011) Susan C. Yanik et al.   TOXICOLOGICAL SCIENCES

The environmental chemical tributyltin chloride (TBT) shows both estrogenic and adipogenic activities in mice which might depend on the exposure dose

(2011) M. Penza et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Organotin intake through fish consumption in Finland

(2010) Riikka Airaksinen et al.   ENVIRONMENTAL RESEARCH

Postnatal Development and Fertility of Offspring from Mice Exposed to Triphenyltin (Fentin) Hydroxide During Pregnancy and Lactation

(2010) Marcia Sarpa et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Disruption of thyroid hormone-dependent hypothalamic set-points by environmental contaminants

(2010) Stéphanie Decherf et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Prenatal Exposure to the Environmental Obesogen Tributyltin Predisposes Multipotent Stem Cells to Become Adipocytes

(2010) Séverine Kirchner et al.   MOLECULAR ENDOCRINOLOGY

Acute exposure to tributyltin induces c-fos activation in the hypothalamic arcuate nucleus of adult male mice

(2010) E. Bo et al.   NEUROTOXICOLOGY

Occurrence and chemical speciation analysis of organotin compounds in the environment: A review

(2010) Regina de Carvalho Oliveira et al.   TALANTA

Sex-dependent aromatase activity in rat offspring after pre- and postnatal exposure to triphenyltin chloride

(2010) Carolin Hobler et al.   TOXICOLOGY

Diagnosis and Classification of Diabetes Mellitus

(2009)   DIABETES CARE

Activation of RXR–PPAR heterodimers by organotin environmental endocrine disruptors

(2009) Albane le Maire et al.   EMBO REPORTS

Triphenyltin chloride induces glucose intolerance by the suppression of insulin release from hamster pancreatic ß-cells

(2009) K. Ogino et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Sex differences in effects on sexual development in rat offspring after pre- and postnatal exposure to triphenyltin chloride

(2009) Konstanze Grote et al.   TOXICOLOGY

Long-term exposure to endogenous levels of tributyltin decreases GluR2 expression and increases neuronal vulnerability to glutamate

(2009) Yusuke Nakatsu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Butyltin Contamination in Industrialized Bays Associated with Intensive Marine Activities in Korea

(2008) Minkyu Choi et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Expression of Peroxisome Proliferator-Activated Receptor-γ in Key Neuronal Subsets Regulating Glucose Metabolism and Energy Homeostasis

(2008) David A. Sarruf et al.   ENDOCRINOLOGY

Aquatic organotin pollution in Taiwan

(2008) Pei-Jie Meng et al.   JOURNAL OF ENVIRONMENTAL MANAGEMENT

Endocrine disruption induced by organotin compounds; organotins function as a powerful agonist for nuclear receptors rather than an aromatase inhibitor

(2008) Tsuyoshi Nakanishi   JOURNAL OF TOXICOLOGICAL SCIENCES

Molecular and neural mediators of leptin action

(2008) Scott A. Robertson et al.   PHYSIOLOGY & BEHAVIOR

Blood levels of organotin compounds and their relation to fish consumption in Finland

(2008) Panu Rantakokko et al.   SCIENCE OF THE TOTAL ENVIRONMENT