The Role of Kiss1 Neurons As Integrators of Endocrine, Metabolic, and Environmental Factors in the Hypothalamic–Pituitary–Gonadal Axis

Kv4.2 channel activity controls intrinsic firing dynamics of arcuate kisspeptin neurons

(2018) Philipe R. F. Mendonça et al.   JOURNAL OF PHYSIOLOGY-LONDON

Evidence That Endogenous Somatostatin Inhibits Episodic, but Not Surge, Secretion of LH in Female Sheep

(2017) Richard B. McCosh et al.   ENDOCRINOLOGY

Crosstalks between kisspeptin neurons and somatostatin neurons are not photoperiod dependent in the ewe hypothalamus

(2017) Laurence Dufourny et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Oxytocin Intranasal Administration Affects Neural Networks Upstream of GNRH Neurons

(2017) Mohammad Saied Salehi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

A molecular census of arcuate hypothalamus and median eminence cell types

(2017) John N Campbell et al.   NATURE NEUROSCIENCE

Definition of the hypothalamic GnRH pulse generator in mice

(2017) Jenny Clarkson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AgRP to Kiss1 neuron signaling links nutritional state and fertility

(2017) Stephanie L. Padilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity

(2017) Renchao Chen et al.   Cell Reports

Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP

(2017) Alexander R. Nectow et al.   Cell Reports

κ-Opioid Receptor Is Colocalized in GnRH and KNDy Cells in the Female Ovine and Rat Brain

(2016) Peyton W. Weems et al.   ENDOCRINOLOGY

Roles of RFRP-3 in the daily and seasonal regulation of reproductive activity in female Syrian hamsters

(2016) Jo B Henningsen et al.   ENDOCRINOLOGY

No Evidence That RFamide-Related Peptide 3 Directly Modulates LH Secretion in the Ewe

(2016) C. Decourt et al.   ENDOCRINOLOGY

Visualisation ofKiss1Neurone Distribution Using a Kiss1-CRE Transgenic Mouse

(2016) S.-H. Yeo et al.   JOURNAL OF NEUROENDOCRINOLOGY

Development of an excitatory kisspeptin projection to the oxytocin system in late pregnancy

(2016) Alexander J. Seymour et al.   JOURNAL OF PHYSIOLOGY-LONDON

Control of puberty onset and fertility by gonadotropin-releasing hormone neurons

(2016) Allan E. Herbison   Nature Reviews Endocrinology

A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons

(2016) D. Gowanlock R. Tervo et al.   NEURON

Defining a novel leptin–melanocortin–kisspeptin pathway involved in the metabolic control of puberty

(2016) Maria Manfredi-Lozano et al.   Molecular Metabolism

Substance P Regulates Puberty Onset and Fertility in the Female Mouse

(2015) Serap Simavli et al.   ENDOCRINOLOGY

Kisspeptin Regulation of Arcuate Neuron Excitability in Kisspeptin Receptor Knockout Mice

(2015) Xinhuai Liu et al.   ENDOCRINOLOGY

The Integrated Hypothalamic Tachykinin-Kisspeptin System as a Central Coordinator for Reproduction

(2015) Víctor M. Navarro et al.   ENDOCRINOLOGY

Conditional Viral Tract Tracing Delineates the Projections of the Distinct Kisspeptin Neuron Populations to Gonadotropin-Releasing Hormone (GnRH) Neurons in the Mouse

(2015) Siew Hoong Yip et al.   ENDOCRINOLOGY

Positive, But Not Negative Feedback Actions of Estradiol in Adult Female Mice Require Estrogen Receptor α in Kisspeptin Neurons

(2015) Sharon L. Dubois et al.   ENDOCRINOLOGY

Electrical properties of kisspeptin neurons and their regulation of GnRH neurons

(2015) Richard Piet et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century

(2015) M. C. Inhorn et al.   HUMAN REPRODUCTION UPDATE

Estrogen Permits Vasopressin Signaling in Preoptic Kisspeptin Neurons in the Female Mouse

(2015) R. Piet et al.   JOURNAL OF NEUROSCIENCE

Monosynaptic Circuit Tracing with Glycoprotein-Deleted Rabies Viruses

(2015) E. M. Callaway et al.   JOURNAL OF NEUROSCIENCE

The Distribution of Substance P and Kisspeptin in the Mediobasal Hypothalamus of the Male Rhesus Monkey and a Comparison of Intravenous Administration of These Peptides to Release GnRH as Reflected by LH Secretion

(2015) Bruna Kalil et al.   NEUROENDOCRINOLOGY

Selective optogenetic activation of arcuate kisspeptin neurons generates pulsatile luteinizing hormone secretion

(2015) Su Young Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estradiol modulates Kiss1 neuronal response to ghrelin

(2014) Renata Frazao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucagon Regulates Hepatic Kisspeptin to Impair Insulin Secretion

(2014) Woo-Jin Song et al.   Cell Metabolism

What optogenetic stimulation is telling us (and failing to tell us) about fast neurotransmitters and neuromodulators in brain circuits for wake–sleep regulation

(2014) Elda Arrigoni et al.   CURRENT OPINION IN NEUROBIOLOGY

Increasing LH Pulsatility in Women With Hypothalamic Amenorrhoea Using Intravenous Infusion of Kisspeptin-54

(2014) Channa N. Jayasena et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity

(2014) Kristen P. Tolson et al.   JOURNAL OF CLINICAL INVESTIGATION

Murine Arcuate Nucleus Kisspeptin Neurons Communicate with GnRH Neurons In Utero

(2014) D. Kumar et al.   JOURNAL OF NEUROSCIENCE

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

(2014) Lukasz Swiech et al.   NATURE BIOTECHNOLOGY

Recent advances in optogenetics and pharmacogenetics

(2013) Gary Aston-Jones et al.   BRAIN RESEARCH

Regulation of Arcuate Neurons Coexpressing Kisspeptin, Neurokinin B, and Dynorphin by Modulators of Neurokinin 3 and κ-Opioid Receptors in Adult Male Mice

(2013) Kristen A. Ruka et al.   ENDOCRINOLOGY

Cocaine- and Amphetamine-Regulated Transcript Is a Potent Stimulator of GnRH and Kisspeptin Cells and May Contribute to Negative Energy Balance-induced Reproductive Inhibition in Females

(2013) Cadence True et al.   ENDOCRINOLOGY

Neurokinin B Activates Arcuate Kisspeptin Neurons Through Multiple Tachykinin Receptors in the Male Mouse

(2013) Simon de Croft et al.   ENDOCRINOLOGY

Kisspeptin, Neurokinin B, and Dynorphin Act in the Arcuate Nucleus to Control Activity of the GnRH Pulse Generator in Ewes

(2013) Robert L. Goodman et al.   ENDOCRINOLOGY

Kisspeptin Neurones do not Directly Signal to RFRP-3 Neurones but RFRP-3 may Directly Modulate a Subset of Hypothalamic Kisspeptin Cells in Mice

(2013) M. C. Poling et al.   JOURNAL OF NEUROENDOCRINOLOGY

Shift in Kiss1 Cell Activity Requires Estrogen Receptor  

(2013) R. Frazao et al.   JOURNAL OF NEUROSCIENCE

GnRH Neurons Elaborate a Long-Range Projection with Shared Axonal and Dendritic Functions

(2013) M. K. Herde et al.   JOURNAL OF NEUROSCIENCE

Cellular-resolution connectomics: challenges of dense neural circuit reconstruction

(2013) Moritz Helmstaedter   NATURE METHODS

Molecular logic of neocortical projection neuron specification, development and diversity

(2013) Luciano Custo Greig et al.   NATURE REVIEWS NEUROSCIENCE

Leptin Signaling in Kiss1 Neurons Arises after Pubertal Development

(2013) Roberta M. Cravo et al.   PLoS One

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Dependence of fertility on kisspeptin–Gpr54 signaling at the GnRH neuron

(2013) Milen Kirilov et al.   Nature Communications

Direct Regulation of GnRH Neuron Excitability by Arcuate Nucleus POMC and NPY Neuron Neuropeptides in Female Mice

(2012) Juan Roa et al.   ENDOCRINOLOGY

Evidence That Dopamine Acts via Kisspeptin to Hold GnRH Pulse Frequency in Check in Anestrous Ewes

(2012) Robert L. Goodman et al.   ENDOCRINOLOGY

Effects of Leptin and Melanocortin Signaling Interactions on Pubertal Development and Reproduction

(2012) Davelene D. Israel et al.   ENDOCRINOLOGY

RFamide-Related Peptide-3 Receptor Gene Expression in GnRH and Kisspeptin Neurons and GnRH-Dependent Mechanism of Action

(2012) Mohammed Z. Rizwan et al.   ENDOCRINOLOGY

Suppression of the GnRH Pulse Generator by Neurokinin B Involves a κ-Opioid Receptor-Dependent Mechanism

(2012) P. Grachev et al.   ENDOCRINOLOGY

Stimulatory Effect of RFRP-3 on the Gonadotrophic Axis in the Male Syrian Hamster: The Exception Proves the Rule

(2012) Caroline Ancel et al.   ENDOCRINOLOGY

Ghrelin Suppresses Secretion of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) in Women

(2012) Michael Kluge et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Kisspeptin-Immunoreactivity Changes in a Sex- and Hypothalamic-Region-Specific Manner Across Rat Postnatal Development

(2012) E. Desroziers et al.   JOURNAL OF NEUROENDOCRINOLOGY

Kisspeptin Restores Pulsatile LH Secretion in Patients with Neurokinin B Signaling Deficiencies: Physiological, Pathophysiological and Therapeutic Implications

(2012) Jacques Young et al.   NEUROENDOCRINOLOGY

Immunohistochemical analysis of the colocalization of corticotropin-releasing hormone receptor and glucocorticoid receptor in kisspeptin neurons in the hypothalamus of female rats

(2012) Ken Takumi et al.   NEUROSCIENCE LETTERS

RFRP neurons are critical gatekeepers for the photoperiodic control of reproduction

(2012) Valérie Simonneaux et al.   Frontiers in Endocrinology

Regulation of NKB Pathways and Their Roles in the Control of Kiss1 Neurons in the Arcuate Nucleus of the Male Mouse

(2011) V. M. Navarro et al.   ENDOCRINOLOGY

Molecular Properties of Kiss1 Neurons in the Arcuate Nucleus of the Mouse

(2011) Michelle L. Gottsch et al.   ENDOCRINOLOGY

Projections of Arcuate Nucleus and Rostral Periventricular Kisspeptin Neurons in the Adult Female Mouse Brain

(2011) Shel-Hwa Yeo et al.   ENDOCRINOLOGY

Identification, Expression, and Physiological Functions of Siberian Hamster Gonadotropin-Inhibitory Hormone

(2011) Takayoshi Ubuka et al.   ENDOCRINOLOGY

Kisspeptin Signaling Is Indispensable for Neurokinin B, but not Glutamate, Stimulation of Gonadotropin Secretion in Mice

(2011) David García-Galiano et al.   ENDOCRINOLOGY

The Inhibitory Effects of Neurokinin B on GnRH Pulse Generator Frequency in the Female Rat

(2011) James S. Kinsey-Jones et al.   ENDOCRINOLOGY

Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus

(2011) Robert Porteous et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Dual Phenotype Kisspeptin-Dopamine Neurones of the Rostral Periventricular Area of the Third Ventricle Project to Gonadotrophin-Releasing Hormone Neurones

(2011) J. Clarkson et al.   JOURNAL OF NEUROENDOCRINOLOGY

Involvement of Neurokinin Receptors in the Control of Pulsatile Luteinizing Hormone Secretion in Rats

(2011) Ken-ichi NORITAKE et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Female reproductive maturation in the absence of kisspeptin/GPR54 signaling

(2011) Christian Mayer et al.   NATURE NEUROSCIENCE

Characterization of the inhibitory roles of RFRP3, the mammalian ortholog of GnIH, in the control of gonadotropin secretion in the rat: in vivo and in vitro studies

(2010) R. Pineda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat

(2010) Víctor M. Navarro et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hypothalamic Expression of KISS1 and Gonadotropin Inhibitory Hormone Genes During the Menstrual Cycle of a Non-Human Primate1

(2010) Jeremy T. Smith et al.   BIOLOGY OF REPRODUCTION

Corticotrophin-releasing factor and stress-induced inhibition of the gonadotrophin-releasing hormone pulse generator in the female

(2010) X.F. Li et al.   BRAIN RESEARCH

Kisspeptin Cells in the Ewe Brain Respond to Leptin and Communicate with Neuropeptide Y and Proopiomelanocortin Cells

(2010) Kathryn Backholer et al.   ENDOCRINOLOGY

Circadian Control of Kisspeptin and a Gated GnRH Response Mediate the Preovulatory Luteinizing Hormone Surge

(2010) Wilbur P. Williams et al.   ENDOCRINOLOGY

Identification of Prolactin-Sensitive GABA and Kisspeptin Neurons in Regions of the Rat Hypothalamus Involved in the Control of Fertility

(2010) Ilona C. Kokay et al.   ENDOCRINOLOGY

Photoperiod and Reproductive Condition Are Associated with Changes in RFamide-Related Peptide (RFRP) Expression in Syrian Hamsters (Mesocricetus auratus)

(2010) Alex O. Mason et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Leptin’s effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons

(2010) Jose Donato et al.   JOURNAL OF CLINICAL INVESTIGATION

Developmental Changes in the Expression of Kisspeptin mRNA in Rat Hypothalamus

(2010) Ken Takumi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Evidence for Suprachiasmatic Vasopressin Neurones Innervating Kisspeptin Neurones in the Rostral Periventricular Area of the Mouse Brain: Regulation by Oestrogen

(2010) B.  Vida et al.   JOURNAL OF NEUROENDOCRINOLOGY

Kisspeptin Directly Excites Anorexigenic Proopiomelanocortin Neurons but Inhibits Orexigenic Neuropeptide Y Cells by an Indirect Synaptic Mechanism

(2010) L.-Y. Fu et al.   JOURNAL OF NEUROSCIENCE

Neurokinin B and Dynorphin A in Kisspeptin Neurons of the Arcuate Nucleus Participate in Generation of Periodic Oscillation of Neural Activity Driving Pulsatile Gonadotropin-Releasing Hormone Secretion in the Goat

(2010) Y. Wakabayashi et al.   JOURNAL OF NEUROSCIENCE

Characterization of Kiss1 neurons using transgenic mouse models

(2010) R.M. Cravo et al.   NEUROSCIENCE

The Role of Kisspeptin Signaling in Reproduction

(2010) Xavier d'Anglemont de Tassigny et al.   PHYSIOLOGY

Timing and completion of puberty in female mice depend on estrogen receptor  -signaling in kisspeptin neurons

(2010) C. Mayer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Embryonic gonadotropin-releasing hormone signaling is necessary for maturation of the male reproductive axis

(2010) S. Wen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex differences in the regulation of Kiss1/NKB neurons in juvenile mice: implications for the timing of puberty

(2009) Alexander S. Kauffman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Estradiol Negative Feedback Regulation by Glutamatergic Afferents to A15 Dopaminergic Neurons: Variation with Season

(2009) Sushma R. Singh et al.   ENDOCRINOLOGY

Subcutaneous Injection of Kisspeptin-54 Acutely Stimulates Gonadotropin Secretion in Women with Hypothalamic Amenorrhea, But Chronic Administration Causes Tachyphylaxis

(2009) Channa N. Jayasena et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Distribution of Kisspeptin Neurones in the Adult Female Mouse Brain

(2009) J. Clarkson et al.   JOURNAL OF NEUROENDOCRINOLOGY

Regulation of Kiss1 and Dynorphin Gene Expression in the Murine Brain by Classical and Nonclassical Estrogen Receptor Pathways

(2009) M. L. Gottsch et al.   JOURNAL OF NEUROSCIENCE

Regulation of Gonadotropin-Releasing Hormone Secretion by Kisspeptin/Dynorphin/Neurokinin B Neurons in the Arcuate Nucleus of the Mouse

(2009) V. M. Navarro et al.   JOURNAL OF NEUROSCIENCE

Advances in viral transneuronal tracing

(2009) Gabriella Ugolini   JOURNAL OF NEUROSCIENCE METHODS

Forebrain projections of arcuate neurokinin B neurons demonstrated by anterograde tract-tracing and monosodium glutamate lesions in the rat

(2009) S.J. Krajewski et al.   NEUROSCIENCE

Inducible gene manipulations in serotonergic neurons

(2009) Tillmann Weber   Frontiers in Molecular Neuroscience

Relaxin-3 stimulates the hypothalamic-pituitary-gonadal axis

(2008) B. M. McGowan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hypothalamic pathways linking energy balance and reproduction

(2008) Jennifer W. Hill et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Potent Action of RFamide-Related Peptide-3 on Pituitary Gonadotropes Indicative of a Hypophysiotropic Role in the Negative Regulation of Gonadotropin Secretion

(2008) Iain J. Clarke et al.   ENDOCRINOLOGY

Variation in Kisspeptin and RFamide-Related Peptide (RFRP) Expression and Terminal Connections to Gonadotropin-Releasing Hormone Neurons in the Brain: A Novel Medium for Seasonal Breeding in the Sheep

(2008) Jeremy T. Smith et al.   ENDOCRINOLOGY

Exogenous kisspeptin does not alter photoperiod-induced gonadal regression in Siberian hamsters (Phodopus sungorus)

(2008) Timothy J. Greives et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Infertility and the provision of infertility medical services in developing countries

(2008) W. Ombelet et al.   HUMAN REPRODUCTION UPDATE

Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female rats

(2008) Masahiro Murakami et al.   JOURNAL OF ENDOCRINOLOGY

RFamide-Related Peptide and its Cognate Receptor in the Sheep: cDNA Cloning, mRNA Distribution in the Hypothalamus and the Effect of Photoperiod

(2008) H. Dardente et al.   JOURNAL OF NEUROENDOCRINOLOGY

Kisspeptin-GPR54 Signaling Is Essential for Preovulatory Gonadotropin-Releasing Hormone Neuron Activation and the Luteinizing Hormone Surge

(2008) J. Clarkson et al.   JOURNAL OF NEUROSCIENCE

Sex steroid control of hypothalamic Kiss1 expression in sheep and rodents: Comparative aspects

(2008) Jeremy T. Smith   PEPTIDES

Photoperiod Influences the Central Effects of Ghrelin on Food Intake, GH and LH Secretion in Sheep

(2007) Joanne L. Harrison et al.   NEUROENDOCRINOLOGY