Optimized dendritic cell vaccination induces potent CD8 T cell responses and anti-tumor effects in transgenic mouse melanoma models

Multiple therapeutic peptide vaccines for patients with advanced gastric cancer

(2017) Yoshiyuki Fujiwara et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Dendritic cell vaccination for metastatic melanoma

(2017) Francesco de Rosa et al.   MELANOMA RESEARCH

An immunogenic personal neoantigen vaccine for patients with melanoma

(2017) Patrick A. Ott et al.   NATURE

The immune contexture in cancer prognosis and treatment

(2017) Wolf H. Fridman et al.   Nature Reviews Clinical Oncology

Myeloid-derived suppressor cells are increased and correlated with type 2 immune responses, malnutrition, inflammation, and poor prognosis in patients with breast cancer

(2017) Kenji Gonda et al.   Oncology Letters

Induction of resident memory T cells enhances the efficacy of cancer vaccine

(2017) Mevyn Nizard et al.   Nature Communications

Myeloid-Derived Suppressor Cells

(2017) Dmitry I. Gabrilovich   Cancer Immunology Research

Trial watch: Dendritic cell-based anticancer immunotherapy

(2017) Abhishek D. Garg et al.   OncoImmunology

Immune Checkpoint Therapy in Melanoma

(2016) Margaret K. Callahan   CANCER JOURNAL

Drug Combinations as the New Standard for Melanoma Treatment

(2016) Marta Polkowska et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Genetically engineered mouse models in oncology research and cancer medicine

(2016) Kelly Kersten et al.   EMBO Molecular Medicine

Overall Survival and Durable Responses in Patients WithBRAFV600–Mutant Metastatic Melanoma Receiving Dabrafenib Combined With Trametinib

(2016) Georgina V. Long et al.   JOURNAL OF CLINICAL ONCOLOGY

Immunotherapy of Melanoma

(2016) Carolin Bender et al.   Oncology Research and Treatment

mRNA-based dendritic cell immunization improves survival in ret transgenic mouse melanoma model

(2016) Adi Sharbi-Yunger et al.   OncoImmunology

Cancer Neoantigens and Applications for Immunotherapy

(2015) A. Desrichard et al.   CLINICAL CANCER RESEARCH

mRNA-transfected Dendritic Cells Expressing Polypeptides That Link MHC-I Presentation to Constitutive TLR4 Activation Confer Tumor Immunity

(2015) Gal Cafri et al.   MOLECULAR THERAPY

Combination cancer immunotherapies tailored to the tumour microenvironment

(2015) Mark J. Smyth et al.   Nature Reviews Clinical Oncology

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

(2015) James Larkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade

(2015) Juan Fu et al.   Science Translational Medicine

Vaccines Combined with Immune Checkpoint Antibodies Promote Cytotoxic T-cell Activity and Tumor Eradication

(2015) O. A. Ali et al.   Cancer Immunology Research

A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice

(2015) Therese Liechtenstein et al.   Oncotarget

Long-term clinical outcome of melanoma patients treated with messenger RNA-electroporated dendritic cell therapy following complete resection of metastases

(2014) Sofie Wilgenhof et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Elevated chronic inflammatory factors and myeloid-derived suppressor cells indicate poor prognosis in advanced melanoma patients

(2014) Huanhuan Jiang et al.   INTERNATIONAL JOURNAL OF CANCER

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

(2014) Mahesh Yadav et al.   NATURE

A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients

(2013) S. Wilgenhof et al.   ANNALS OF ONCOLOGY

Antitumor Effect of Paclitaxel Is Mediated by Inhibition of Myeloid-Derived Suppressor Cells and Chronic Inflammation in the Spontaneous Melanoma Model

(2013) A. Sevko et al.   JOURNAL OF IMMUNOLOGY

At the Bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy

(2013) Margaret K. Callahan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Messenger RNA-based vaccines: progress, challenges, applications

(2013) Thomas Kramps et al.   Wiley Interdisciplinary Reviews-RNA

Transnuclear TRP1-Specific CD8 T Cells with High or Low Affinity TCRs Show Equivalent Antitumor Activity

(2013) S. K. Dougan et al.   Cancer Immunology Research

Dendritic Cells: Master Regulators of the Immune Response

(2013) I. Mellman   Cancer Immunology Research

Preclinical Evaluation of TriMix and Antigen mRNA-Based Antitumor Therapy

(2012) S. Van Lint et al.   CANCER RESEARCH

Vaccine-Induced Effector-Memory CD8+ T Cell Responses Predict Therapeutic Efficacy against Tumors

(2012) S. van Duikeren et al.   JOURNAL OF IMMUNOLOGY

Application of paclitaxel in low non-cytotoxic doses supports vaccination with melanoma antigens in normal mice

(2012) Alexandra Sevko et al.   Journal of Immunotoxicology

Coupling presentation of MHC class I peptides to constitutive activation of antigen-presenting cells through the product of a single gene

(2011) G. Cafri et al.   INTERNATIONAL IMMUNOLOGY

Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model

(2011) C. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The immunologic aspects in advanced ovarian cancer patients treated with paclitaxel and carboplatin chemotherapy

(2009) Xia Wu et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Optimized Peptide Vaccines Eliciting Extensive CD8 T-Cell Responses with Therapeutic Antitumor Effects

(2009) H.-I. Cho et al.   CANCER RESEARCH

PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4+CD25Hi regulatory T cells

(2009) Wenshi Wang et al.   INTERNATIONAL IMMUNOLOGY

Population alterations of l-arginase- and inducible nitric oxide synthase-expressed CD11b+/CD14−/CD15+/CD33+ myeloid-derived suppressor cells and CD8+ T lymphocytes in patients with advanced-stage non-small cell lung cancer

(2009) Chien-Ying Liu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

BrafV600E cooperates with Pten loss to induce metastatic melanoma

(2009) David Dankort et al.   NATURE GENETICS

Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas

(2008) Caroline Kannengiesser et al.   Molecular Oncology

The role of viral nucleic acid recognition in dendritic cells for innate and adaptive antiviral immunity

(2007) Katharina Eisenächer et al.   IMMUNOBIOLOGY