Triptolide prevents osteoarthritis via inhibiting hsa-miR-20b

Spliceosome-Associated Protein 130 Exacerbates Alcohol-Induced Liver Injury by Inducing NLRP3 Inflammasome–Mediated IL-1β in Mice

(2018) Jong-Won Kim et al.   AMERICAN JOURNAL OF PATHOLOGY

Preoperative Risk Factors for Postoperative Falls in Persons Undergoing Hip or Knee Arthroplasty: A Longitudinal Study of Data From the Osteoarthritis Initiative

(2018) Daniel L. Riddle et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

The NLRP3 inflammasome: Role in metabolic disorders and regulation by metabolic pathways

(2018) Danlu Jiang et al.   CANCER LETTERS

NLRP3, un inflammasome sous contrôle

(2018) Marine Groslambert et al.   M S-MEDECINE SCIENCES

The knee, osteoarthritis and biomarkers

(2018) J.M. Farber   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis, cerebrovascular dysfunction and the common denominator of inflammation: a narrative review

(2018) B.K. Al-Khazraji et al.   OSTEOARTHRITIS AND CARTILAGE

Clinimetrics of ultrasound pathologies in osteoarthritis: systematic literature review and meta-analysis

(2018) W.M. Oo et al.   OSTEOARTHRITIS AND CARTILAGE

miR-10b is a prognostic marker in clear cell renal cell carcinoma

(2017) Heba W Z Khella et al.   JOURNAL OF CLINICAL PATHOLOGY

Triptolide-Assisted Phosphorylation of p53 Suppresses Inflammation-Induced NF-κB Survival Pathways in Cancer Cells

(2017) Li Zheng et al.   MOLECULAR AND CELLULAR BIOLOGY

p38α has an important role in antigen cross-presentation by dendritic cells

(2016) Yifan Zhou et al.   Cellular & Molecular Immunology

Free fatty acids sensitize dendritic cells to amplify TH1/TH17-immune responses

(2016) Kristin Stelzner et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Triptolide Modulates TREM-1 Signal Pathway to Inhibit the Inflammatory Response in Rheumatoid Arthritis

(2016) Danping Fan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Triptolide Attenuates Inflammatory Response in Membranous Glomerulo-Nephritis Rat via Downregulation of NF-κB Signaling Pathway

(2016) Ying Zhou et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Triptolide reduces proliferation and enhances apoptosis of human non-small cell lung cancer cells through PTEN by targeting miR-21

(2016) XIAOFANG LI et al.   Molecular Medicine Reports

Anti-cancer and Sensibilisation Effect of Triptolide on Human Epithelial Ovarian Cancer

(2016) Hui Hu et al.   Journal of Cancer

The Role of Innate Immunity in Osteoarthritis: When Our First Line of Defense Goes On the Offensive

(2015) E. W. Orlowsky et al.   JOURNAL OF RHEUMATOLOGY

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

Evidence for Involvement of Spinal RANTES in the Antinociceptive Effects of Triptolide, a Diterpene Triepoxide, in a Rat Model of Bone Cancer Pain

(2014) Li-Hua Hang et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Anti-inflammatory Effects of Triptolide in LPS-Induced Acute Lung Injury in Mice

(2014) Dong Wei et al.   INFLAMMATION

Inhibitory effects of triptolide on titanium particle-induced osteolysis and receptor activator of nuclear factor-κB ligand-mediated osteoclast differentiation

(2014) Ju Ang Kim et al.   INTERNATIONAL ORTHOPAEDICS

Anti-inflammatory effects of triptolide by inhibiting the NF-κB signalling pathway in LPS-induced acute lung injury in a murine model

(2014) XIAN WANG et al.   Molecular Medicine Reports

A novel benzo[d]imidazole derivate prevents the development of dextran sulfate sodium-induced murine experimental colitis via inhibition of NLRP3 inflammasome

(2013) Wen Liu et al.   BIOCHEMICAL PHARMACOLOGY

Triptolide Prevents Bone Destruction in the Collagen-Induced Arthritis Model of Rheumatoid Arthritis by Targeting RANKL/RANK/OPG Signal Pathway

(2013) Chunfang Liu et al.   Evidence-based Complementary and Alternative Medicine

Anti-Angiogenic Effect of Triptolide in Rheumatoid Arthritis by Targeting Angiogenic Cascade

(2013) Xiangying Kong et al.   PLoS One

Efficacy of Triptolide for Children with Moderately Severe Henoch-Schönlein Purpura Nephritis Presenting with Nephrotic Range Proteinuria: A Prospective and Controlled Study in China

(2013) Li Wu et al.   Biomed Research International

Synovium and the Innate Inflammatory Network in Osteoarthritis Progression

(2013) Ru Liu-Bryan   Current Rheumatology Reports

A systematic review and meta-analysis comparing complications following total joint arthroplasty for rheumatoid arthritis versus for osteoarthritis

(2012) Bheeshma Ravi et al.   ARTHRITIS AND RHEUMATISM

Triptolide in the treatment of psoriasis and other immune-mediated inflammatory diseases

(2012) Rui Han et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Triptolide ameliorates Crohn's colitis is associated with inhibition of TLRs/NF-κB signaling pathway

(2011) Chao Yu et al.   FITOTERAPIA

Inhibition of differentiation, amplification, and function of human TH17 cells by intravenous immunoglobulin

(2011) Mohan S. Maddur et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Triptolide-induced apoptosis by inactivating nuclear factor-kappa B apoptotic pathway in multiple myeloma in vitro

(2011) Rong Zeng et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation

(2011) Anna E. Denoble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triptolide ameliorates IL-10-deficient mice colitis by mechanisms involving suppression of IL-6/STAT3 signaling pathway and down-regulation of IL-17

(2010) Yi Li et al.   MOLECULAR IMMUNOLOGY

NLRP3/Cryopyrin Is Necessary for Interleukin-1β (IL-1β) Release in Response to Hyaluronan, an Endogenous Trigger of Inflammation in Response to Injury

(2009) Kenshi Yamasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Innate immune system activation in osteoarthritis: is osteoarthritis a chronic wound?

(2008) Carla R Scanzello et al.   CURRENT OPINION IN RHEUMATOLOGY

Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis

(2008) Ying Wang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Triptolide protects podocytes from puromycin aminonucleoside induced injury in vivo and in vitro

(2008) Chun-Xia Zheng et al.   KIDNEY INTERNATIONAL