Pre-Activation of Toll-Like Receptor 2 Enhances CD8+ T-Cell Responses and Accelerates Hepatitis B Virus Clearance in the Mouse Models

Local Stimulation of Liver Sinusoidal Endothelial Cells with a NOD1 Agonist Activates T Cells and Suppresses Hepatitis B Virus Replication in Mice

(2018) Shunmei Huang et al.   JOURNAL OF IMMUNOLOGY

TLR2 Stimulation Strengthens Intrahepatic Myeloid-Derived Cell-Mediated T Cell Tolerance through Inducing Kupffer Cell Expansion and IL-10 Production

(2018) Jia Liu et al.   JOURNAL OF IMMUNOLOGY

Low hepatitis B virus-specific T-cell response in males correlates with high regulatory T-cell numbers in murine models

(2017) Anna D. Kosinska et al.   HEPATOLOGY

Hepatitis B virus evades innate immunity of hepatocytes but activates cytokine production by macrophages

(2017) Xiaoming Cheng et al.   HEPATOLOGY

Transforming growth factor β-activated kinase 1 transcriptionally suppresses hepatitis B virus replication

(2017) Jinke Pang et al.   Scientific Reports

TLR2 Expression in Peripheral CD4+ T Cells Promotes Th17 Response and Is Associated with Disease Aggravation of Hepatitis B Virus-Related Acute-On-Chronic Liver Failure

(2017) Chunli Xu et al.   Frontiers in Immunology

The role of innate immunity in the immunopathology and treatment of HBV infection

(2016) Mala K. Maini et al.   JOURNAL OF HEPATOLOGY

Hepatitis B virus genome replication triggers toll-like receptor 3-dependent interferon responses in the absence of hepatitis B surface antigen

(2016) Catherine Isabell Real et al.   Scientific Reports

Aberrant expression and dysfunction of TLR2 and its soluble form in chronic HBV infection and its regulation by antiviral therapy

(2015) Zuxiong Huang et al.   ANTIVIRAL RESEARCH

Host–virus interactions in hepatitis B virus infection

(2015) Luca G Guidotti et al.   CURRENT OPINION IN IMMUNOLOGY

Molecular biology of hepatitis B virus infection

(2015) Christoph Seeger et al.   VIROLOGY

Persistence of the Recombinant Genomes of Woodchuck Hepatitis Virus in the Mouse Model

(2015) Danzhen Pan et al.   PLoS One

Contribution of Toll-like receptors to the control of hepatitis B virus infection by initiating antiviral innate responses and promoting specific adaptive immune responses

(2014) Zhiyong Ma et al.   Cellular & Molecular Immunology

Poly(I:C) Treatment Leads to Interferon-Dependent Clearance of Hepatitis B Virus in a Hydrodynamic Injection Mouse Model

(2014) J. Wu et al.   JOURNAL OF VIROLOGY

Toll-like receptor (TLR)-mediated innate immune responses in the control of hepatitis B virus (HBV) infection

(2014) Ejuan Zhang et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Antibody Responses during Hepatitis B Viral Infection

(2014) Stanca M. Ciupe et al.   PLoS Computational Biology

TLR1/2 Ligand-Stimulated Mouse Liver Endothelial Cells Secrete IL-12 and Trigger CD8+ T Cell Immunity In Vitro

(2013) J. Liu et al.   JOURNAL OF IMMUNOLOGY

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8+ T cells and successful immunotherapy against chronic viral liver infection

(2013) Li-Rung Huang et al.   NATURE IMMUNOLOGY

The innate immune response to hepatitis B virus infection: Implications for pathogenesis and therapy

(2012) Jinhong Chang et al.   ANTIVIRAL RESEARCH

Preclinical development of TLR ligands as drugs for the treatment of chronic viral infections

(2012) Xiaoyong Zhang et al.   Expert Opinion on Drug Discovery

Role of Toll-like receptor 2 in the immune response against hepadnaviral infection

(2012) Xiaoyong Zhang et al.   JOURNAL OF HEPATOLOGY

TNF-Induced Target Cell Killing by CTL Activated through Cross-Presentation

(2012) Dirk Wohlleber et al.   Cell Reports

Bridging Innate and Adaptive Immunity

(2011) William E. Paul   CELL

The host–pathogen interaction during HBV infection: immunological controversies

(2010) Antonio Bertoletti et al.   ANTIVIRAL THERAPY

When Toll-like receptor and T-cell receptor signals collide: a mechanism for enhanced CD8 T-cell effector function

(2010) D. Geng et al.   BLOOD

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Lipopolysaccharide-induced innate immune responses in primary hepatocytes downregulates woodchuck hepatitis virus replication via interferon-independent pathways

(2009) Xiaoyong Zhang et al.   CELLULAR MICROBIOLOGY