Alkaline pH Promotes NADPH Oxidase-Independent Neutrophil Extracellular Trap Formation: A Matter of Mitochondrial Reactive Oxygen Species Generation and Citrullination and Cleavage of Histone

Diverse stimuli engage different neutrophil extracellular trap pathways

(2017) Elaine F Kenny et al.   eLife

Extracellular Acidification Inhibits the ROS-Dependent Formation of Neutrophil Extracellular Traps

(2017) Martina Behnen et al.   Frontiers in Immunology

Pondering neutrophil extracellular traps with healthy skepticism

(2016) William M. Nauseef et al.   CELLULAR MICROBIOLOGY

Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis

(2016) Moritz Leppkes et al.   Nature Communications

Ménage-à-Trois: The Ratio of Bicarbonate to CO2 and the pH Regulate the Capacity of Neutrophils to Form NETs

(2016) Christian Maueröder et al.   Frontiers in Immunology

Multimodal Regulation of NET Formation in Pregnancy: Progesterone Antagonizes the Pro-NETotic Effect of Estrogen and G-CSF

(2016) Stavros Giaglis et al.   Frontiers in Immunology

New Insights into Neutrophil Extracellular Traps: Mechanisms of Formation and Role in Inflammation

(2016) Hang Yang et al.   Frontiers in Immunology

Extracellular Acidification Acts as a Key Modulator of Neutrophil Apoptosis and Functions

(2015) Shannan Cao et al.   PLoS One

SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx

(2015) David Nobuhiro Douda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium and ROS: A mutual interplay

(2015) Agnes Görlach et al.   Redox Biology

Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity

(2015) Adam P. Levine et al.   PLoS One

Classical ROS-dependent and early/rapid ROS-independent release of Neutrophil Extracellular Traps triggered by Leishmania parasites

(2015) Natalia C. Rochael et al.   Scientific Reports

Histone Deimination As a Response to Inflammatory Stimuli in Neutrophils

(2014) I. Neeli et al.   JOURNAL OF IMMUNOLOGY

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Efficient Neutrophil Extracellular Trap Induction Requires Mobilization of Both Intracellular and Extracellular Calcium Pools and Is Modulated by Cyclosporine A

(2014) Anurag Kumar Gupta et al.   PLoS One

A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis

(2014) Kathleen D. Metzler et al.   Cell Reports

Uric acid induces NADPH oxidase-independent neutrophil extracellular trap formation

(2013) Yasuyuki Arai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NETosis: how vital is it?

(2013) B. G. Yipp et al.   BLOOD

An Extracellular Matrix-Based Mechanism of Rapid Neutrophil Extracellular Trap Formation in Response to Candida albicans

(2013) A. S. Byrd et al.   JOURNAL OF IMMUNOLOGY

NET balancing: a problem in inflammatory lung diseases

(2013) Olivia Z. Cheng et al.   Frontiers in Immunology

A SerpinB1 Regulatory Mechanism Is Essential for Restricting Neutrophil Extracellular Trap Generation

(2012) Kalamo Farley et al.   JOURNAL OF IMMUNOLOGY

Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus

(2012) Heather Parker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo

(2012) Bryan G Yipp et al.   NATURE MEDICINE

PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures

(2012) Marc Leshner et al.   Frontiers in Immunology

Activation of PAD4 in NET formation

(2012) Amanda S. Rohrbach et al.   Frontiers in Immunology

Review: Staphylococcus aureus and MRSA in cystic fibrosis

(2011) Christopher H. Goss et al.   Journal of Cystic Fibrosis

Functional Role of Dimerization of Human Peptidylarginine Deiminase 4 (PAD4)

(2011) Yi-Liang Liu et al.   PLoS One

PAD4-Mediated Neutrophil Extracellular Trap Formation Is Not Required for Immunity against Influenza Infection

(2011) Saskia Hemmers et al.   PLoS One

Acid and base secretion in freshly excised nasal tissue from cystic fibrosis patients with ΔF508 mutation

(2011) Do-Yeon Cho et al.   International Forum of Allergy & Rhinology

Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity

(2010) K. D. Metzler et al.   BLOOD

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

(2010) Pingxin Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Leishmania donovani Promastigotes Evade the Antimicrobial Activity of Neutrophil Extracellular Traps

(2010) C. Gabriel et al.   JOURNAL OF IMMUNOLOGY

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Inhibition of superoxide anion production by extracellular acidification in neutrophils

(2009) Naoya Murata et al.   CELLULAR IMMUNOLOGY

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Regulation of Extracellular Chromatin Release from Neutrophils

(2009) Indira Neeli et al.   Journal of Innate Immunity

Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition

(2008) Magnus J. Hansson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of superoxide production in neutrophils: role of calcium influx

(2008) Sabrina Bréchard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neutrophil elastase, proteinase 3 and cathepsin G: Physicochemical properties, activity and physiopathological functions

(2007) Brice Korkmaz et al.   BIOCHIMIE