Expression of Tumor Necrosis Factor Receptor 2 Characterizes TLR9-Driven Formation of Interleukin-10-Producing B Cells

TNFα in the regulation of Treg and Th17 cells in rheumatoid arthritis and other autoimmune inflammatory diseases

(2018) Jonas Bystrom et al.   CYTOKINE

Transmembrane tumor necrosis factor-α promotes the recruitment of MDSCs to tumor tissue by upregulating CXCR4 expression via TNFR2

(2017) Hongping Ba et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs

(2017) Heather Torrey et al.   Science Signaling

Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs

(2017) Heather Torrey et al.   Science Signaling

Control of GVHD by regulatory T cells depends on TNF produced by T cells and TNFR2 expressed by regulatory T cells

(2016) M. Leclerc et al.   BLOOD

Porphyromonas gingivalis Outer Membrane Vesicles Induce Selective Tumor Necrosis Factor Tolerance in a Toll-Like Receptor 4- and mTOR-Dependent Manner

(2016) Tobias Waller et al.   INFECTION AND IMMUNITY

Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion

(2016) Martin Chopra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy

(2016) Geoffrey S. Williams et al.   Oncotarget

A TNFR2-Agonist Facilitates High Purity Expansion of Human Low Purity Treg Cells

(2016) Xuehui He et al.   PLoS One

Regulatory B cells in CVID patients fail to suppress multifunctional IFN-γ+TNF-α+CD4+ T cells differentiation

(2015) Marcela Vlkova et al.   CLINICAL IMMUNOLOGY

Interleukin-10 Modulates Antigen Presentation by Dendritic Cells through Regulation of NLRP3 Inflammasome Assembly during Chlamydia Infection

(2015) Yusuf Omosun et al.   INFECTION AND IMMUNITY

Suppressive functions of B cells in infectious diseases: Fig. 1.

(2015) Ping Shen et al.   INTERNATIONAL IMMUNOLOGY

TNF biology, pathogenic mechanisms and emerging therapeutic strategies

(2015) George D. Kalliolias et al.   Nature Reviews Rheumatology

Rapid Proliferation and Differentiation of a Subset of Circulating IgM Memory B Cells to a CpG/Cytokine Stimulus In Vitro

(2015) Camilo Vásquez et al.   PLoS One

From the regulatory functions of B cells to the identification of cytokine-producing plasma cell subsets

(2014) Van Duc Dang et al.   CURRENT OPINION IN IMMUNOLOGY

TNF and TNF-receptors: From mediators of cell death and inflammation to therapeutic giants – past, present and future

(2014) Lisa M. Sedger et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Autocrine IL-10 promotes human B-cell differentiation into IgM- or IgG-secreting plasmablasts

(2014) Guido Heine et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ca2+-related signaling events influence TLR9-induced IL-10 secretion in human B cells

(2014) Saskia Ziegler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation

(2014) Masanori Matsumoto et al.   IMMUNITY

IL-10-producing regulatory B cells induced by IL-33 (BregIL-33) effectively attenuate mucosal inflammatory responses in the gut

(2014) Susanne Sattler et al.   JOURNAL OF AUTOIMMUNITY

TLR9-Activating DNA Up-Regulates ZAP70 via Sustained PKB Induction in IgM+ B Cells

(2014) I. Bekeredjian-Ding et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: TNFR-Shedding by CD4+CD25+ Regulatory T Cells Inhibits the Induction of Inflammatory Mediators

(2014) G. J. D. van Mierlo et al.   JOURNAL OF IMMUNOLOGY

CpG Drives Human Transitional B Cells to Terminal Differentiation and Production of Natural Antibodies

(2014) F. Capolunghi et al.   JOURNAL OF IMMUNOLOGY

IRAK4 turns IL-10+phospho-FOXO+monocytes into pro-inflammatory cells by suppression of protein kinase B

(2013) Benjamin Over et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immune control of Staphylococcus aureus – Regulation and counter-regulation of the adaptive immune response

(2013) Barbara M. Bröker et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Transmembrane TNF-  Promotes Suppressive Activities of Myeloid-Derived Suppressor Cells via TNFR2

(2013) X. Hu et al.   JOURNAL OF IMMUNOLOGY

Pathogen-Triggered Activation of Plasmacytoid Dendritic Cells Induces IL-10-Producing B Cells in Response to Staphylococcus aureus

(2013) M. Parcina et al.   JOURNAL OF IMMUNOLOGY

Asymptomatic Plasmodial Infection Is Associated With Increased Tumor Necrosis Factor Receptor II–Expressing Regulatory T Cells and Suppressed Type 2 Immune Responses

(2013) Linda J. Wammes et al.   JOURNAL OF INFECTIOUS DISEASES

Differential expression of TNFR1 (CD120a) and TNFR2 (CD120b) on subpopulations of human monocytes

(2013) Daniëlle Hijdra et al.   Journal of Inflammation-London

Quantitative flow cytometric analysis of expression of tumor necrosis factor receptor types I and II on mononuclear cells

(2013) Julia A. Lopatnikova et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

TNF signaling drives myeloid-derived suppressor cell accumulation

(2012) Xueqiang Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

TNFR1-induced activation of the classical NF-κB pathway

(2011) Harald Wajant et al.   FEBS Journal

The Calcium Sensors STIM1 and STIM2 Control B Cell Regulatory Function through Interleukin-10 Production

(2011) Masanori Matsumoto et al.   IMMUNITY

The phenotypic and functional consequences of tumour necrosis factor receptor type 2 expression on CD4+ FoxP3+ regulatory T cells

(2011) Xin Chen et al.   IMMUNOLOGY

NFATc1 affects mouse splenic B cell function by controlling the calcineurin–NFAT signaling network

(2011) Sankar Bhattacharyya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Natural but Not Inducible Regulatory T Cells Require TNF-  Signaling for In Vivo Function

(2011) W. J. Housley et al.   JOURNAL OF IMMUNOLOGY

A TNF Receptor 2 Selective Agonist Rescues Human Neurons from Oxidative Stress-Induced Cell Death

(2011) Roman Fischer et al.   PLoS One

TLR9 Ligand Induces the Generation of CD20+ Plasmablasts and Plasma Cells from CD27+ Memory B-Cells

(2011) Alexandrine Geffroy-Luseau et al.   Frontiers in Immunology

Pathogenic T cells have a paradoxical protective effect in murine autoimmune diabetes by boosting Tregs

(2010) Yenkel Grinberg-Bleyer et al.   JOURNAL OF CLINICAL INVESTIGATION

TNF receptor 2 pathway: drug target for autoimmune diseases

(2010) Denise Faustman et al.   NATURE REVIEWS DRUG DISCOVERY

Transmembrane TNF- : structure, function and interaction with anti-TNF agents

(2010) T. Horiuchi et al.   RHEUMATOLOGY

Membrane Tumor Necrosis Factor (TNF) Induces p100 Processing via TNF Receptor-2 (TNFR2)

(2009) Hilka Rauert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-TNF-induced lupus

(2009) E. L. Williams et al.   RHEUMATOLOGY

Parasite-Dependent Expansion of TNF Receptor II–Positive Regulatory T Cells with Enhanced Suppressive Activity in Adults with Severe Malaria

(2009) Gabriela Minigo et al.   PLoS Pathogens

1,25-dihydroxyvitamin D3promotes IL-10 production in human B cells

(2008) Guido Heine et al.   EUROPEAN JOURNAL OF IMMUNOLOGY