A TNFR2-Agonist Facilitates High Purity Expansion of Human Low Purity Treg Cells

Transmembrane TNF–TNFR2 Impairs Th17 Differentiation by PromotingIl2Expression

(2015) Patrick G. Miller et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Foxp3-Mediated Induction of Pim 2 Allows Human T Regulatory Cells to Preferentially Expand in Rapamycin

(2014) Samik Basu et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: TNFR-Shedding by CD4+CD25+ Regulatory T Cells Inhibits the Induction of Inflammatory Mediators

(2014) G. J. D. van Mierlo et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells as Immunotherapy

(2014) Benjamin D. Singer et al.   Frontiers in Immunology

Human secondary lymphoid organs typically contain polyclonally-activated proliferating regulatory T cells

(2013) J. H. Peters et al.   BLOOD

TNFR2 Is Critical for the Stabilization of the CD4+Foxp3+ Regulatory T Cell Phenotype in the Inflammatory Environment

(2013) X. Chen et al.   JOURNAL OF IMMUNOLOGY

Helios+ and Helios- Cells Coexist within the Natural FOXP3+ T Regulatory Cell Subset in Humans

(2013) M. E. Himmel et al.   JOURNAL OF IMMUNOLOGY

Targeting PKC in Human T Cells Using Sotrastaurin (AEB071) Preserves Regulatory T Cells and Prevents IL-17 Production

(2013) Xuehui He et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis

(2013) Hong Nie et al.   NATURE MEDICINE

Homogeneous Expansion of Human T-Regulatory Cells Via Tumor Necrosis Factor Receptor 2

(2013) Yoshiaki Okubo et al.   Scientific Reports

Regulatory T Cells Exhibit Decreased Proliferation but Enhanced Suppression After Pulsing With Sirolimus

(2012) K. Singh et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+FOXP3+ T regulatory cell subpopulations

(2012) C. Scotta et al.   HAEMATOLOGICA

Humanized Mouse Model of Skin Inflammation Is Characterized by Disturbed Keratinocyte Differentiation and Influx of IL-17A Producing T Cells

(2012) Vivian L. de Oliveira et al.   PLoS One

Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells

(2011) E. Tresoldi et al.   HAEMATOLOGICA

Increased thioredoxin-1 production in human naturally occurring regulatory T cells confers enhanced tolerance to oxidative stress

(2010) D. Mougiakakos et al.   BLOOD

Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+regulatory T cells in human peripheral blood

(2010) Xin Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Isolation and expansion of human natural T regulatory cells for cellular therapy

(2010) Rajendra Pahwa et al.   JOURNAL OF IMMUNOLOGICAL METHODS

TNF Activates a NF- B-Regulated Cellular Program in Human CD45RA- Regulatory T Cells that Modulates Their Suppressive Function

(2010) M. Nagar et al.   JOURNAL OF IMMUNOLOGY

In vivo prevention of transplant arteriosclerosis by ex vivo–expanded human regulatory T cells

(2010) Satish N Nadig et al.   NATURE MEDICINE

Cutting Edge: Responder T Cells Regulate Human DR+ Effector Regulatory T Cell Activity via Granzyme B

(2009) C. W. Ashley et al.   JOURNAL OF IMMUNOLOGY

Identification of IL-17-producing FOXP3+ regulatory T cells in humans

(2009) K. S. Voo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

(2008) H. J. P. M. Koenen et al.   BLOOD

Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127pos Depletion, Treg Expansion, and Treg Cryopreservation

(2008) Jorieke H. Peters et al.   PLoS One