High-Mobility Group Nucleosome-Binding Protein 1 as Endogenous Ligand Induces Innate Immune Tolerance in a TLR4-Sirtuin-1 Dependent Manner in Human Blood Peripheral Mononuclear Cells

The Alarmin HMGN1 Contributes to Antitumor Immunity and Is a Potent Immunoadjuvant

(2014) F. Wei et al.   CANCER RESEARCH

SIRT1 inhibition during the hypoinflammatory phenotype of sepsis enhances immunity and improves outcome

(2014) Vidula T. Vachharajani et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

(2014) Andrew A Lane et al.   NATURE GENETICS

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

HMGN1 Modulates Nucleosome Occupancy and DNase I Hypersensitivity at the CpG Island Promoters of Embryonic Stem Cells

(2013) Tao Deng et al.   MOLECULAR AND CELLULAR BIOLOGY

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS–NO–nitrite signaling

(2013) Ibrahim Yazji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

NAD+-dependent Sirtuin 1 and 6 Proteins Coordinate a Switch from Glucose to Fatty Acid Oxidation during the Acute Inflammatory Response

(2012) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TLR2 and TLR4 Mediate Differential Responses to Limb Ischemia through MyD88-Dependent and Independent Pathways

(2012) Ulka Sachdev et al.   PLoS One

HMGB1, an alarmin promoting HIV dissemination and latency in dendritic cells

(2011) M-L Gougeon et al.   CELL DEATH AND DIFFERENTIATION

NAD+-dependent SIRT1 Deacetylase Participates in Epigenetic Reprogramming during Endotoxin Tolerance

(2011) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses

(2011) De Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

HMGB1, a potent proinflammatory cytokine in sepsis

(2010) Wenchang Huang et al.   CYTOKINE

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase II 

(2009) M. Stros et al.   NUCLEIC ACIDS RESEARCH

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(2008) John Klune et al.   MOLECULAR MEDICINE