Many Routes to an Antibody Heavy-Chain CDR3: Necessary, Yet Insufficient, for Specific Binding

Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens

(2018) Jeff DeFalco et al.   CLINICAL IMMUNOLOGY

Assessment of antibody library diversity through next generation sequencing and technical error compensation

(2017) Marco Fantini et al.   PLoS One

Structural diversity in a human antibody germline library

(2016) Alexey Teplyakov et al.   mAbs

Next generation sequencing of all variable loops of synthetic single framework scFv—Application in anti-HDL antibody selections

(2016) Janita Lövgren et al.   New Biotechnology

Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires

(2016) Brandon J. DeKosky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Robust estimates of overall immune-repertoire diversity from high-throughput measurements on samples

(2016) Joseph Kaplinsky et al.   Nature Communications

Accurate and predictive antibody repertoire profiling by molecular amplification fingerprinting

(2016) T. A. Khan et al.   Science Advances

A Public Database of Memory and Naive B-Cell Receptor Sequences

(2016) William S. DeWitt et al.   PLoS One

Next-generation sequencing and protein mass spectrometry for the comprehensive analysis of human cellular and serum antibody repertoires

(2015) Jason J Lavinder et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Deep sequencing in library selection projects: what insight does it bring?

(2015) J Glanville et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing

(2015) Konstantinos Tsioris et al.   Integrative Biology

Analysis of Celiac Disease Autoreactive Gut Plasma Cells and Their Corresponding Memory Compartment in Peripheral Blood Using High-Throughput Sequencing

(2015) Omri Snir et al.   JOURNAL OF IMMUNOLOGY

Inferring processes underlying B-cell repertoire diversity

(2015) Yuval Elhanati et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Quantitative assessment of the robustness of next-generation sequencing of antibody variable gene repertoires from immunized mice

(2014) Victor Greiff et al.   BMC IMMUNOLOGY

Human Responses to Influenza Vaccination Show Seroconversion Signatures and Convergent Antibody Rearrangements

(2014) Katherine J.L. Jackson et al.   Cell Host & Microbe

Identifying functional anti-Staphylococcus aureus antibodies by sequencing antibody repertoires of patient plasmablasts

(2014) Daniel R. Lu et al.   CLINICAL IMMUNOLOGY

High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination

(2014) Yann-Chong Tan et al.   CLINICAL IMMUNOLOGY

Large scale production of phage antibody libraries using a bioreactor

(2014) Fortunato Ferrara et al.   mAbs

Recombinant renewable polyclonal antibodies

(2014) Fortunato Ferrara et al.   mAbs

In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire

(2014) Brandon J DeKosky et al.   NATURE MEDICINE

Antibody repertoire deep sequencing reveals antigen-independent selection in maturing B cells

(2014) J. Kaplinsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and characterization of the constituent human serum antibodies elicited by vaccination

(2014) Jason J. Lavinder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-resolution antibody dynamics of vaccine-induced immune responses

(2014) Uri Laserson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From deep sequencing to actual clones

(2014) S. D'Angelo et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Using phage display selected antibodies to dissect microbiomes for complete de novo genome sequencing of low abundance microbes

(2013) Devin W Close et al.   BMC MICROBIOLOGY

Convergent Antibody Signatures in Human Dengue

(2013) Poornima Parameswaran et al.   Cell Host & Microbe

Single-cell based high-throughput sequencing of full-length immunoglobulin heavy and light chain genes

(2013) Christian E. Busse et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Specific binder for Lightning-Link® biotinylated proteins from an antibody phage library

(2013) Fortunato Ferrara et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The Restricted DH Gene Reading Frame Usage in the Expressed Human Antibody Repertoire Is Selected Based upon its Amino Acid Content

(2013) J. Benichou et al.   JOURNAL OF IMMUNOLOGY

Comprehensive Interrogation of a Minimalist Synthetic CDR-H3 Library and Its Ability to Generate Antibodies with Therapeutic Potential

(2013) Ciara M. Mahon et al.   JOURNAL OF MOLECULAR BIOLOGY

The antibody mining toolbox

(2013) Sara D'Angelo et al.   mAbs

Deep sequencing of phage display libraries to support antibody discovery

(2013) Ulla Ravn et al.   METHODS

IgBLAST: an immunoglobulin variable domain sequence analysis tool

(2013) Jian Ye et al.   NUCLEIC ACIDS RESEARCH

Lineage Structure of the Human Antibody Repertoire in Response to Influenza Vaccination

(2013) N. Jiang et al.   Science Translational Medicine

The Application of Next Generation Sequencing to the Understanding of Antibody Repertoires

(2013) Pascale Mathonet et al.   Frontiers in Immunology

CDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic Antibodies

(2012) Helena Persson et al.   JOURNAL OF MOLECULAR BIOLOGY

Antibody Repertoires in Humanized NOD-scid-IL2Rγnull Mice and Human B Cells Reveals Human-Like Diversification and Tolerance Checkpoints in the Mouse

(2012) Gregory C. Ippolito et al.   PLoS One

Transferring the Characteristics of Naturally Occurring and Biased Antibody Repertoires to Human Antibody Libraries by Trapping CDRH3 Sequences

(2012) Sophie Venet et al.   PLoS One

Using Phage and Yeast Display to Select Hundreds of Monoclonal Antibodies: Application to Antigen 85, a Tuberculosis Biomarker

(2012) Fortunato Ferrara et al.   PLoS One

Selection of a CXCR4 antagonist from a human heavy chain CDR3-derived phage library

(2011) Andy Chevigné et al.   FEBS Journal

High-Resolution Description of Antibody Heavy-Chain Repertoires in Humans

(2011) Ramy Arnaout et al.   PLoS One

Development of Phage-Based Single Chain Fv Antibody Reagents for Detection of Yersinia pestis

(2011) Antonietta M. Lillo et al.   PLoS One

A New Clustering of Antibody CDR Loop Conformations

(2010) Benjamin North et al.   JOURNAL OF MOLECULAR BIOLOGY

By-passing in vitro screening—next generation sequencing technologies applied to antibody display and in silico candidate selection

(2010) U. Ravn et al.   NUCLEIC ACIDS RESEARCH

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

(2009) J. Glanville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH

IMGT(R), the international ImMunoGeneTics information system(R)

(2008) M.-P. Lefranc et al.   NUCLEIC ACIDS RESEARCH

Using T7 phage display to select GFP-based binders

(2008) M. Dai et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Non-immunized natural human heavy chain CDR3 repertoires allow the isolation of high affinity peptides mimicking a human influenza hemagglutinin epitope

(2007) Sabrina Deroo et al.   MOLECULAR IMMUNOLOGY