A Tumor Vascular-Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia

WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice

(2018) Volker Neuschmelting et al.   Theranostics

Padeliporfin vascular-targeted photodynamic therapy versus active surveillance in men with low-risk prostate cancer

(2017) Weigang Yan et al.   LANCET ONCOLOGY

Targeting Phosphatidylinositol 3-Kinase Signaling Pathway for Therapeutic Enhancement of Vascular-Targeted Photodynamic Therapy

(2017) Daniel Kraus et al.   MOLECULAR CANCER THERAPEUTICS

Manipulating tumor hypoxia toward enhanced photodynamic therapy (PDT)

(2017) Juanjuan Dang et al.   Biomaterials Science

Theranostic Liposomes with Hypoxia-Activated Prodrug to Effectively Destruct Hypoxic Tumors Post-Photodynamic Therapy

(2016) Liangzhu Feng et al.   ACS Nano

Stimuli responsive drug delivery systems based on nano-graphene for cancer therapy

(2016) Kai Yang et al.   ADVANCED DRUG DELIVERY REVIEWS

Dual delivery of biological therapeutics for multimodal and synergistic cancer therapies

(2016) Bora Jang et al.   ADVANCED DRUG DELIVERY REVIEWS

Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy

(2016) Chenggen Qian et al.   ADVANCED MATERIALS

Tumor priming using metronomic chemotherapy with neovasculature-targeted, nanoparticulate paclitaxel

(2016) Xin Luan et al.   BIOMATERIALS

Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells

(2016) Rong Sun et al.   BIOMATERIALS

Tumor acidity-sensitive linkage-bridged block copolymer for therapeutic siRNA delivery

(2016) Cong-Fei Xu et al.   BIOMATERIALS

Enhancement of cell adhesion, retention, and survival of HUVEC/cbMSC aggregates that are transplanted in ischemic tissues by concurrent delivery of an antioxidant for therapeutic angiogenesis

(2016) Chieh-Cheng Huang et al.   BIOMATERIALS

Hypoxia-activated prodrugs: paths forward in the era of personalised medicine

(2016) Francis W Hunter et al.   BRITISH JOURNAL OF CANCER

Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugs

(2016) Roger M. Phillips   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Antiangiogenic therapy in oncology: current status and future directions

(2016) Gordon C Jayson et al.   LANCET

A photoactivable multi-inhibitor nanoliposome for tumour control and simultaneous inhibition of treatment escape pathways

(2016) Bryan Q. Spring et al.   Nature Nanotechnology

Sphingomyelin Liposomes Containing Porphyrin-phospholipid for Irinotecan Chemophototherapy

(2016) Kevin A Carter et al.   Theranostics

Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin αvβ3

(2016) Haojun Chen et al.   Theranostics

Multifunctional Polymeric Nanosystems for Dual-Targeted Combinatorial Chemo/Antiangiogenesis Therapy of Tumors

(2016) Fatima Zohra Dahmani et al.   Advanced Healthcare Materials

Chemophototherapy: An Emerging Treatment Option for Solid Tumors

(2016) Dandan Luo et al.   Advanced Science

Hypoxia Induced by Upconversion-Based Photodynamic Therapy: Towards Highly Effective Synergistic Bioreductive Therapy in Tumors

(2015) Yanyan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Delta-like ligand 4-targeted nanomedicine for antiangiogenic cancer therapy

(2015) Ya-Rong Liu et al.   BIOMATERIALS

Oxygen-Enhanced MRI Accurately Identifies, Quantifies, and Maps Tumor Hypoxia in Preclinical Cancer Models

(2015) J. P. B. O'Connor et al.   CANCER RESEARCH

Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)

(2015) Ulrich Lächelt et al.   CHEMICAL REVIEWS

H2O2-Activatable and O2-Evolving Nanoparticles for Highly Efficient and Selective Photodynamic Therapy against Hypoxic Tumor Cells

(2015) Huachao Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multifunctional ultrasmall nanoplatforms for vascular-targeted interstitial photodynamic therapy of brain tumors guided by real-time MRI

(2015) Denise Bechet et al.   Nanomedicine-Nanotechnology Biology and Medicine

Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy

(2015) Yuhao Cheng et al.   Nature Communications

Spherical Cancer Models in Tumor Biology

(2015) Louis-Bastien Weiswald et al.   NEOPLASIA

Tumor Vasculature Targeted Photodynamic Therapy for Enhanced Delivery of Nanoparticles

(2014) Zipeng Zhen et al.   ACS Nano

MSN-Mediated Sequential Vascular-to-Cell Nuclear-Targeted Drug Delivery for Efficient Tumor Regression

(2014) Limin Pan et al.   ADVANCED MATERIALS

Hypoxia-Targeted siRNA Delivery

(2014) F. Perche et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer

(2014) M T Huggett et al.   BRITISH JOURNAL OF CANCER

The role of strong hypoxia in tumors after treatment in the outcome of bacteriochlorin-based photodynamic therapy

(2014) Martyna Krzykawska-Serda et al.   FREE RADICAL BIOLOGY AND MEDICINE

Low-dose angiostatic tyrosine kinase inhibitors improve photodynamic therapy for cancer: lack of vascular normalization

(2014) Andrea Weiss et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Triple negative breast cancer therapy with CDK1 siRNA delivered by cationic lipid assisted PEG-PLA nanoparticles

(2014) Yang Liu et al.   JOURNAL OF CONTROLLED RELEASE

PEGylation of magnetic poly(glycidyl methacrylate) microparticles for microfluidic bioassays

(2014) Jana Kucerova et al.   Materials Science & Engineering C-Materials for Biological Applications

The use of nanoparticulate delivery systems in metronomic chemotherapy

(2013) De-Hong Yu et al.   BIOMATERIALS

Polyethylene Glycol and Polyethylenimine Dual-Functionalized Nano-Graphene Oxide for Photothermally Enhanced Gene Delivery

(2013) Liangzhu Feng et al.   Small

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia

(2012) Annamaria Rapisarda et al.   Nature Reviews Clinical Oncology

Multifunctional Peptide-Conjugated Hybrid Silica Nanoparticles for Photodynamic Therapy and MRI

(2012) Hamanou Benachour et al.   Theranostics

Photodynamic therapy of cancer: An update

(2011) Patrizia Agostinis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The effect and clinical consequences of hypoxia on cytochrome P450, membrane carrier proteins activity and expression

(2011) Patrick du Souich et al.   Expert Opinion on Drug Metabolism & Toxicology

Angiostatic kinase inhibitors to sustain photodynamic angio-occlusion

(2011) Patrycja Nowak-Sliwinska et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The in vivo behavior and antitumor activity of doxorubicin-loaded poly(γ-benzyl l-glutamate)-block-hyaluronan polymersomes in Ehrlich ascites tumor-bearing BalB/c mice

(2011) Kamal Kumar Upadhyay et al.   Nanomedicine-Nanotechnology Biology and Medicine

Antitumor immunity promoted by vascular occluding therapy: lessons from vascular-targeted photodynamic therapy (VTP)

(2011) Dina Preise et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

A new 18F-labeled BBN-RGD peptide heterodimer with a symmetric linker for prostate cancer imaging

(2010) Yongjun Yan et al.   AMINO ACIDS

Assessment and Monitoring Tumor Vascularity With Contrast-Enhanced Ultrasound Maximum Intensity Persistence Imaging

(2010) Marybeth A. Pysz et al.   INVESTIGATIVE RADIOLOGY

The Hypoxia-Activated ProDrug AQ4N Penetrates Deeply in Tumor Tissues and Complements the Limited Distribution of Mitoxantrone

(2009) O. Tredan et al.   CANCER RESEARCH

Clustering and Internalization of Integrin αvβ3 With a Tetrameric RGD-synthetic Peptide

(2009) Sancey Lucie et al.   MOLECULAR THERAPY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Functional Graphene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Mixed Anticancer Drugs

(2009) Liming Zhang et al.   Small

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Generation of Singlet Oxygen via the Composites of Water-Soluble Thiol-Capped CdTe Quantum DotsSulfonated Aluminum Phthalocyanines

(2008) Jiong Ma et al.   JOURNAL OF PHYSICAL CHEMISTRY B

PEGylated Nanographene Oxide for Delivery of Water-Insoluble Cancer Drugs

(2008) Zhuang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Preparation of peptide-conjugated quantum dots for tumor vasculature-targeted imaging

(2008) Weibo Cai et al.   Nature Protocols