Manipulating tumor hypoxia toward enhanced photodynamic therapy (PDT)

Theoretical model for optical oximetry at the capillary level: exploring hemoglobin oxygen saturation through backscattering of single red blood cells

(2017) Rongrong Liu et al.   JOURNAL OF BIOMEDICAL OPTICS

Drug-induced co-assembly of albumin/catalase as smart nano-theranostics for deep intra-tumoral penetration, hypoxia relieve, and synergistic combination therapy

(2017) Qian Chen et al.   JOURNAL OF CONTROLLED RELEASE

Overcoming the Limits of Hypoxia in Photodynamic Therapy: A Carbonic Anhydrase IX-Targeted Approach

(2017) Hyo Sung Jung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions

(2017) Demian van Straten et al.   Cancers

A Donor–Acceptor Conjugated Polymer with Alternating Isoindigo Derivative and Bithiophene Units for Near-Infrared Modulated Cancer Thermo-Chemotherapy

(2016) Dong-Dong Li et al.   ACS Applied Materials & Interfaces

Tumor Microenvironment and Angiogenic Blood Vessels Dual-Targeting for Enhanced Anti-Glioma Therapy

(2016) Quanyin Hu et al.   ACS Applied Materials & Interfaces

Carbon-Dot-Decorated Carbon Nitride Nanoparticles for Enhanced Photodynamic Therapy against Hypoxic Tumor via Water Splitting

(2016) Di-Wei Zheng et al.   ACS Nano

Red Blood Cell-Facilitated Photodynamic Therapy for Cancer Treatment

(2016) Wei Tang et al.   ADVANCED FUNCTIONAL MATERIALS

Intelligent Albumin-MnO2Nanoparticles as pH-/H2O2-Responsive Dissociable Nanocarriers to Modulate Tumor Hypoxia for Effective Combination Therapy

(2016) Qian Chen et al.   ADVANCED MATERIALS

Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy

(2016) Chenggen Qian et al.   ADVANCED MATERIALS

Perfluorocarbon-Loaded Hollow Bi2Se3Nanoparticles for Timely Supply of Oxygen under Near-Infrared Light to Enhance the Radiotherapy of Cancer

(2016) Guosheng Song et al.   ADVANCED MATERIALS

Direct Photocontrol of Peptidomimetics: An Alternative to Oxygen-Dependent Photodynamic Cancer Therapy

(2016) Oleg Babii et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A highly tumor-specific light-triggerable drug carrier responds to hypoxic tumor conditions for effective tumor treatment

(2016) Wooram Park et al.   BIOMATERIALS

Activatable albumin-photosensitizer nanoassemblies for triple-modal imaging and thermal-modulated photodynamic therapy of cancer

(2016) Dehong Hu et al.   BIOMATERIALS

The hypoxia-related signaling pathways of vasculogenic mimicry in tumor treatment

(2016) Shuixian Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Hypoxia-activated prodrugs: paths forward in the era of personalised medicine

(2016) Francis W Hunter et al.   BRITISH JOURNAL OF CANCER

Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugs

(2016) Roger M. Phillips   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Light-controlled reactive oxygen species (ROS)-producible polymeric micelles with simultaneous drug-release triggering and endo/lysosomal escape

(2016) Kihong Kim et al.   CHEMICAL COMMUNICATIONS

NIR light/H2O2-triggered nanocomposites for a highly efficient and selective synergistic photodynamic and photothermal therapy against hypoxic tumor cells

(2016) Yu Zhang et al.   CHEMICAL COMMUNICATIONS

Overcoming the Achilles' heel of photodynamic therapy

(2016) Wenpei Fan et al.   CHEMICAL SOCIETY REVIEWS

Azido- and chlorido-cobalt complex as carrier-prototypes for antitumoral prodrugs

(2016) Bianca M. Pires et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Hyaluronidase To Enhance Nanoparticle-Based Photodynamic Tumor Therapy

(2016) Hua Gong et al.   NANO LETTERS

Ultrasound Triggered Tumor Oxygenation with Oxygen-Shuttle Nanoperfluorocarbon to Overcome Hypoxia-Associated Resistance in Cancer Therapies

(2016) Xuejiao Song et al.   NANO LETTERS

Inhibition of hypoxia-inducible factor 1 with acriflavine sensitizes hypoxic tumor cells to photodynamic therapy with zinc phthalocyanine-encapsulating cationic liposomes

(2016) Mans Broekgaarden et al.   Nano Research

Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs

(2016) Liam J O'Connor et al.   Nature Protocols

The anti-tumor efficacy of 3-(2-Nitrophenyl) propionic acid-paclitaxel (NPPA-PTX): a novel paclitaxel bioreductive prodrug

(2016) Ping Song et al.   Oncotarget

Enhancing Photodynamic Therapy Efficacy by Using Fluorinated Nanoplatform

(2016) Yurong Que et al.   ACS Macro Letters

Poly(trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

(2016) K. Fukushima   Biomaterials Science

Enhancing tissue integration and angiogenesis of a novel nanocomposite polymer using plasma surface polymerisation, an in vitro and in vivo study

(2016) Michelle F. Griffin et al.   Biomaterials Science

Near-infrared photothermal therapy of Prussian-blue-functionalized lanthanide-ion-doped inorganic/plasmonic multifunctional nanostructures for the selective targeting of HER2-expressing breast cancer cells

(2016) Abdul K. Parchur et al.   Biomaterials Science

Fabrication of dendrimer-releasing lipidic nanoassembly for cancer drug delivery

(2016) Qihang Sun et al.   Biomaterials Science

Modeling the tumor microenvironment using chitosan-alginate scaffolds to control the stem-like state of glioblastoma cells

(2016) Forrest M. Kievit et al.   Biomaterials Science

Biomedical applications of nano-titania in theranostics and photodynamic therapy

(2016) F. U. Rehman et al.   Biomaterials Science

Magnetic and fluorescent carbon-based nanohybrids for multi-modal imaging and magnetic field/NIR light responsive drug carriers

(2016) Hui Wang et al.   Biomaterials Science

Folic acid conjugated magnetic iron oxide nanoparticles for nondestructive separation and detection of ovarian cancer cells from whole blood

(2016) Wenting Liu et al.   Biomaterials Science

pH- and NIR light responsive nanocarriers for combination treatment of chemotherapy and photodynamic therapy

(2016) Sheng Wang et al.   Biomaterials Science

Liquid crystalline nanoparticles encapsulating cisplatin and docetaxel combination for targeted therapy of breast cancer

(2016) Raj Kumar Thapa et al.   Biomaterials Science

Calcium phosphate-based organic–inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy

(2016) Takahiro Nomoto et al.   Biomaterials Science

Near infrared imaging-guided photodynamic therapy under an extremely low energy of light by galactose targeted amphiphilic polypeptide micelle encapsulating BODIPY-Br2

(2016) Le Liu et al.   Biomaterials Science

Nano-formulation of a photosensitizer using a DNA tetrahedron and its potential for in vivo photodynamic therapy

(2016) Kyoung-Ran Kim et al.   Biomaterials Science

Functional nanomaterials for near-infrared-triggered cancer therapy

(2016) Bei Liu et al.   Biomaterials Science

Self-Monitoring Artificial Red Cells with Sufficient Oxygen Supply for Enhanced Photodynamic Therapy

(2016) Zhenyu Luo et al.   Scientific Reports

UV-Emitting Upconversion-Based TiO2 Photosensitizing Nanoplatform: Near-Infrared Light Mediated in Vivo Photodynamic Therapy via Mitochondria-Involved Apoptosis Pathway

(2015) Zhiyao Hou et al.   ACS Nano

Self-Assembled Core–Shell Nanoparticles for Combined Chemotherapy and Photodynamic Therapy of Resistant Head and Neck Cancers

(2015) Chunbai He et al.   ACS Nano

Intelligent MnO2Nanosheets Anchored with Upconversion Nanoprobes for Concurrent pH-/H2O2-Responsive UCL Imaging and Oxygen-Elevated Synergetic Therapy

(2015) Wenpei Fan et al.   ADVANCED MATERIALS

Hypoxia Induced by Upconversion-Based Photodynamic Therapy: Towards Highly Effective Synergistic Bioreductive Therapy in Tumors

(2015) Yanyan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Hemoglobin Conjugated Polymeric Micelle: A ZnPc Carrier with Oxygen Self-Compensating Ability for Photodynamic Therapy

(2015) Shasha Wang et al.   BIOMACROMOLECULES

Hypoxia and hypoxia inducible factors in tumor metabolism

(2015) Wen Zeng et al.   CANCER LETTERS

Nanoparticle delivery of HIF1α siRNA combined with photodynamic therapy as a potential treatment strategy for head-and-neck cancer

(2015) Wei-Hua Chen et al.   CANCER LETTERS

H2O2-Activatable and O2-Evolving Nanoparticles for Highly Efficient and Selective Photodynamic Therapy against Hypoxic Tumor Cells

(2015) Huachao Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photodynamic therapy (PDT) of cancer: from local to systemic treatment

(2015) Janusz M. Dąbrowski et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy

(2015) Yuhao Cheng et al.   Nature Communications

Developments in PDT Sensitizers for Increased Selectivity and Singlet Oxygen Production

(2015) Nahid Mehraban et al.   Materials

Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy

(2015) Ruud Weijer et al.   Oncotarget

Photomediated Reactive Oxygen Species-Generable Nanoparticles for Triggered Release and Endo/Lysosomal Escape of Drug upon Attenuated Single Light Irradiation

(2015) Eun Ha Seo et al.   Advanced Healthcare Materials

Redox-responsive supramolecular amphiphiles constructed via host–guest interactions for photodynamic therapy

(2015) Feng Liu et al.   Biomaterials Science

Photodynamic therapy (PDT) using HPPH for the treatment of precancerous lesions associated with barrett's esophagus

(2015) Hector R. Nava et al.   LASERS IN SURGERY AND MEDICINE

Polyphosphoester-Based Nanoparticles with Viscous Flow Core Enhanced Therapeutic Efficacy by Improved Intracellular Drug Release

(2014) Yin-Chu Ma et al.   ACS Applied Materials & Interfaces

Multifunctional Theranostic Red Blood Cells For Magnetic-Field-Enhanced in vivo Combination Therapy of Cancer

(2014) Chao Wang et al.   ADVANCED MATERIALS

Low-dose angiostatic tyrosine kinase inhibitors improve photodynamic therapy for cancer: lack of vascular normalization

(2014) Andrea Weiss et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Visible Light-Driven Pure Water Splitting by a Nature-Inspired Organic Semiconductor-Based System

(2014) David James Martin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Investigating the optimal size of anticancer nanomedicine

(2014) L. Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly Discriminating Photorelease of Anticancer Drugs Based on Hypoxia Activatable Phototrigger Conjugated Chitosan Nanoparticles

(2013) Qiuning Lin et al.   ADVANCED MATERIALS

Graphene-Based Materials for Hydrogen Generation from Light-Driven Water Splitting

(2013) Guancai Xie et al.   ADVANCED MATERIALS

Perfluorocarbon Nanoparticles for Physiological and Molecular Imaging and Therapy

(2013) Junjie Chen et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

(2013) Gregg L. Semenza   JOURNAL OF CLINICAL INVESTIGATION

Oxygen saturation and perfusion changes during dermatological methylaminolaevulinate photodynamic therapy

(2011) J. Tyrrell et al.   BRITISH JOURNAL OF DERMATOLOGY

Circadian clocks in human red blood cells

(2011) John S. O’Neill et al.   NATURE

Increasing the efficiency of photodynamic therapy by improved light delivery and oxygen supply using an anticoagulant in a solid tumor model

(2010) Liyong Yang et al.   LASERS IN SURGERY AND MEDICINE

Oncologic photodynamic therapy photosensitizers: A clinical review

(2010) Ron R. Allison et al.   Photodiagnosis and Photodynamic Therapy

Perfluorocarbon Nanoemulsions for Quantitative Molecular Imaging and Targeted Therapeutics

(2009) Megan M. Kaneda et al.   ANNALS OF BIOMEDICAL ENGINEERING

Photodynamic therapy with meta-tetrahydroxyphenylchlorin (Foscan®) in the management of squamous cell carcinoma of the head and neck: experience with 35 patients

(2009) Kai Johannes Lorenz et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

New Light on an Old Problem

(2008) James E. Muller   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY